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The map label for this gene is pbpE [H]

Identifier: 152974835

GI number: 152974835

Start: 1148921

End: 1149997

Strand: Direct

Name: pbpE [H]

Synonym: Bcer98_1031

Alternate gene names: 152974835

Gene position: 1148921-1149997 (Clockwise)

Preceding gene: 152974832

Following gene: 152974837

Centisome position: 28.11

GC content: 34.08

Gene sequence:

>1077_bases
ATGAAACTCAAGCAACGTTTTAACTTAGCTTCTGTATCAAAACCCCTAACAGCATTAGGTATTTTACTATTAGTGCAAGA
AAATAAAATCAAATTAGATGATGATATTAACAAATGGTTTGCAAATTTACCTTATGATAATATTACTGTACGCCACCTTT
TACAACACACATCAGGTTTACCTGATTATATAGAATTGTTTGCTGATCATTGGAACGAATCAACATTTGCTTCAAATGAA
GATGTGCTACAACTCTTAACTCAATATGCACCACCTCGGCTCTTTGAAGCAGGTGAACAAATGGTATATAGCAATACAGG
GTATGTATTATTATCCCTGTTGATTGAGCGTGTTACGAATAAGAGTTTTTCTACGTATATGACTGAAGCGATCTTTAATC
CATTAAATATGAAACATACAACAGTAACTTCAACTACTTTTATAGAGGAATATCCTTGTGAAATTGCACAAGTATATGTA
TATGATGTTTATAGTGGCAAACATATTAGGCCTGTTGAATTTGAAGAAACTAGGGATACTGTTTATTTAGATTATATTAC
CGGTGATGGAGGAATTTATTCAACGGTGGAGGACTTATGGAAATTAGGGCGTGCTGTCATTTGTGCGCAACTTTGGAATA
AAGAATTGCTTGAACAAGCTTTTACTCCATCAACTCTTTCGGCAGAACAATCTTTTCCTTACGGTATGGGATGGATGATA
TATGAAGATGAACAACTGGGAACATGCGTGTCCCATACTGGTGGTTGGCCAGGCTATGCAGCCACCTTTAAAATTTTTCT
TCAATCTAAAACAATCTTTGTCTTTTTACGTAGTAAAGAGCAAGGATTAACCTACGAACAAGCGATTGAAAAGGCACTAA
AAACAAATGAATTAATCTTACCAAAAAAACCTAAGCAACTGAAAGCTATACATTTATCAACTGAATTATTGGAAGGATAT
GTGGGAAAATACTATTTACAAGAGAATCCTGAATATGCGATTGAGGTGGTATTACAACCCAATAATCGCTTATATATATT
TACCAAATACAATGCCAATGGAATTACATGCAATTAA

Upstream 100 bases:

>100_bases
AGATTGAAAATACGTTTAATGGCACGATATTGCTTGCACAAGATAAAAAATTCTATTACAAGGTGCCTATGGAGAAGCTT
CTATTCAAACACATGCTCCA

Downstream 100 bases:

>100_bases
TGAGAATGAATTTTTTTTACGTAGTATAGAAGTTTTAATAACGATTAAACAAAATATATTAACTGTTATTGACGGAGATC
AAAAAACGATCGCAATAAAA

Product: beta-lactamase

Products: NA

Alternate protein names: PBP 4*; PBP 4A; Penicillin-binding protein E [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKLKQRFNLASVSKPLTALGILLLVQENKIKLDDDINKWFANLPYDNITVRHLLQHTSGLPDYIELFADHWNESTFASNE
DVLQLLTQYAPPRLFEAGEQMVYSNTGYVLLSLLIERVTNKSFSTYMTEAIFNPLNMKHTTVTSTTFIEEYPCEIAQVYV
YDVYSGKHIRPVEFEETRDTVYLDYITGDGGIYSTVEDLWKLGRAVICAQLWNKELLEQAFTPSTLSAEQSFPYGMGWMI
YEDEQLGTCVSHTGGWPGYAATFKIFLQSKTIFVFLRSKEQGLTYEQAIEKALKTNELILPKKPKQLKAIHLSTELLEGY
VGKYYLQENPEYAIEVVLQPNNRLYIFTKYNANGITCN

Sequences:

>Translated_358_residues
MKLKQRFNLASVSKPLTALGILLLVQENKIKLDDDINKWFANLPYDNITVRHLLQHTSGLPDYIELFADHWNESTFASNE
DVLQLLTQYAPPRLFEAGEQMVYSNTGYVLLSLLIERVTNKSFSTYMTEAIFNPLNMKHTTVTSTTFIEEYPCEIAQVYV
YDVYSGKHIRPVEFEETRDTVYLDYITGDGGIYSTVEDLWKLGRAVICAQLWNKELLEQAFTPSTLSAEQSFPYGMGWMI
YEDEQLGTCVSHTGGWPGYAATFKIFLQSKTIFVFLRSKEQGLTYEQAIEKALKTNELILPKKPKQLKAIHLSTELLEGY
VGKYYLQENPEYAIEVVLQPNNRLYIFTKYNANGITCN
>Mature_358_residues
MKLKQRFNLASVSKPLTALGILLLVQENKIKLDDDINKWFANLPYDNITVRHLLQHTSGLPDYIELFADHWNESTFASNE
DVLQLLTQYAPPRLFEAGEQMVYSNTGYVLLSLLIERVTNKSFSTYMTEAIFNPLNMKHTTVTSTTFIEEYPCEIAQVYV
YDVYSGKHIRPVEFEETRDTVYLDYITGDGGIYSTVEDLWKLGRAVICAQLWNKELLEQAFTPSTLSAEQSFPYGMGWMI
YEDEQLGTCVSHTGGWPGYAATFKIFLQSKTIFVFLRSKEQGLTYEQAIEKALKTNELILPKKPKQLKAIHLSTELLEGY
VGKYYLQENPEYAIEVVLQPNNRLYIFTKYNANGITCN

Specific function: Probably involved in peptidoglycan modification during cortex synthesis [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550934, Length=163, Percent_Identity=31.9018404907975, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR021860 [H]

Pfam domain/function: PF00144 Beta-lactamase; PF11954 DUF3471 [H]

EC number: NA

Molecular weight: Translated: 41102; Mature: 41102

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKQRFNLASVSKPLTALGILLLVQENKIKLDDDINKWFANLPYDNITVRHLLQHTSGL
CCCHHHCCHHHHCCHHHHHEEEEEEECCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCCC
PDYIELFADHWNESTFASNEDVLQLLTQYAPPRLFEAGEQMVYSNTGYVLLSLLIERVTN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCEEECCCHHHHHHHHHHHHCC
KSFSTYMTEAIFNPLNMKHTTVTSTTFIEEYPCEIAQVYVYDVYSGKHIRPVEFEETRDT
CCHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCE
VYLDYITGDGGIYSTVEDLWKLGRAVICAQLWNKELLEQAFTPSTLSAEQSFPYGMGWMI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
YEDEQLGTCVSHTGGWPGYAATFKIFLQSKTIFVFLRSKEQGLTYEQAIEKALKTNELIL
EECCHHCHHHHCCCCCCCHHHEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHCCCEEC
PKKPKQLKAIHLSTELLEGYVGKYYLQENPEYAIEVVLQPNNRLYIFTKYNANGITCN
CCCCCHHHEEHHHHHHHHHHHCEEEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MKLKQRFNLASVSKPLTALGILLLVQENKIKLDDDINKWFANLPYDNITVRHLLQHTSGL
CCCHHHCCHHHHCCHHHHHEEEEEEECCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCCC
PDYIELFADHWNESTFASNEDVLQLLTQYAPPRLFEAGEQMVYSNTGYVLLSLLIERVTN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCEEECCCHHHHHHHHHHHHCC
KSFSTYMTEAIFNPLNMKHTTVTSTTFIEEYPCEIAQVYVYDVYSGKHIRPVEFEETRDT
CCHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCE
VYLDYITGDGGIYSTVEDLWKLGRAVICAQLWNKELLEQAFTPSTLSAEQSFPYGMGWMI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
YEDEQLGTCVSHTGGWPGYAATFKIFLQSKTIFVFLRSKEQGLTYEQAIEKALKTNELIL
EECCHHCHHHHCCCCCCCHHHEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHCCCEEC
PKKPKQLKAIHLSTELLEGYVGKYYLQENPEYAIEVVLQPNNRLYIFTKYNANGITCN
CCCCCHHHEEHHHHHHHHHHHCEEEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491712; 9384377 [H]