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The map label for this gene is resD [H]

Identifier: 152974825

GI number: 152974825

Start: 1138480

End: 1139151

Strand: Direct

Name: resD [H]

Synonym: Bcer98_1021

Alternate gene names: 152974825

Gene position: 1138480-1139151 (Clockwise)

Preceding gene: 152974824

Following gene: 152974826

Centisome position: 27.86

GC content: 37.65

Gene sequence:

>672_bases
ATGAACAAATATAAAGTATTACTTGTTGATGACGAGAGTGATATGAGGCAACTTGTTGGTATGTACTTAGACAACTTTGG
TTATGAATGGGATGAAGCGGAAAATGGAAAAGAGGCACTTTTAAAATTAGAAGAGGCGCATTATGATTTTGTTATTTTAG
ATATTATGATGCCAGAGATGGATGGAATTGCCGTTTGTAAAGAAATTAGGAAAACATCAGATATTCCGATTATTTTTTTA
ACGGCTAAGGGAGAAGAATGGAATCGAGTAAATGGTTTACGAAATGGTGCGGATGATTATGTTGTGAAGCCATTTAGTCC
CGGGGAGCTGATTGCACGCATGGAAGCTGTACTCAGACGATATACAAAGCAAGGGCAACAAGAAGAATTGGAATTTGGCC
CAATACGTATGAATGAAAAAAGCAGGAAGGCTGAAACGAACGGAAAAATCATTTCCCTTACAGTAAAAGAATTTGATTTA
TTATATTTTCTTTGCCAGCACCATGGCCAAGTATTTAGCCGAGAGCAGTTATTAGAGAAAGTATGGGGATATGACTATGC
AGGAAGTACAAGAACGGTGGATACACATGTGAAAACAATGCGTTTGAAACTAGGAGAAAGCGGAAACTGCATCCAAACAG
TTTGGGGTGTAGGATATAAATTTGAGGTGTAA

Upstream 100 bases:

>100_bases
ACGAAGTGTATATCATTGATATAAAGGATATGAAGATAAAACAAACGGTTGCAGTTGGCAAAGGGCCATTTCACTTGACT
GAGAGAGAGGAGAGAGAAAA

Downstream 100 bases:

>100_bases
TATGTTTACAATGGTACAGAAGCTATGGCTTACAGTTGTATGTGCAGTATGTATAACAGTTTCTTTTCTTTACTTTGTGT
CATTGTACTCGTATGAAAAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNKYKVLLVDDESDMRQLVGMYLDNFGYEWDEAENGKEALLKLEEAHYDFVILDIMMPEMDGIAVCKEIRKTSDIPIIFL
TAKGEEWNRVNGLRNGADDYVVKPFSPGELIARMEAVLRRYTKQGQQEELEFGPIRMNEKSRKAETNGKIISLTVKEFDL
LYFLCQHHGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNCIQTVWGVGYKFEV

Sequences:

>Translated_223_residues
MNKYKVLLVDDESDMRQLVGMYLDNFGYEWDEAENGKEALLKLEEAHYDFVILDIMMPEMDGIAVCKEIRKTSDIPIIFL
TAKGEEWNRVNGLRNGADDYVVKPFSPGELIARMEAVLRRYTKQGQQEELEFGPIRMNEKSRKAETNGKIISLTVKEFDL
LYFLCQHHGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNCIQTVWGVGYKFEV
>Mature_223_residues
MNKYKVLLVDDESDMRQLVGMYLDNFGYEWDEAENGKEALLKLEEAHYDFVILDIMMPEMDGIAVCKEIRKTSDIPIIFL
TAKGEEWNRVNGLRNGADDYVVKPFSPGELIARMEAVLRRYTKQGQQEELEFGPIRMNEKSRKAETNGKIISLTVKEFDL
LYFLCQHHGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNCIQTVWGVGYKFEV

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=39.6396396396396, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=40.2654867256637, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=36.8421052631579, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=35.1598173515982, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=36.9369369369369, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.7777777777778, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=36.697247706422, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.8407079646018, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=35.7798165137615, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.7272727272727, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=31.0810810810811, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=30.1724137931034, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=27.8026905829596, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=42.9906542056075, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=38.3333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=33.8235294117647, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=37.1428571428571, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=121, Percent_Identity=31.404958677686, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25795; Mature: 25795

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYKVLLVDDESDMRQLVGMYLDNFGYEWDEAENGKEALLKLEEAHYDFVILDIMMPEM
CCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCC
DGIAVCKEIRKTSDIPIIFLTAKGEEWNRVNGLRNGADDYVVKPFSPGELIARMEAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHH
YTKQGQQEELEFGPIRMNEKSRKAETNGKIISLTVKEFDLLYFLCQHHGQVFSREQLLEK
HHHCCCHHCCCCCCEEECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
VWGYDYAGSTRTVDTHVKTMRLKLGESGNCIQTVWGVGYKFEV
HCCCCCCCCCCCHHHHHEEEEEECCCCCCHHHHHHCCCEEECC
>Mature Secondary Structure
MNKYKVLLVDDESDMRQLVGMYLDNFGYEWDEAENGKEALLKLEEAHYDFVILDIMMPEM
CCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCC
DGIAVCKEIRKTSDIPIIFLTAKGEEWNRVNGLRNGADDYVVKPFSPGELIARMEAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHH
YTKQGQQEELEFGPIRMNEKSRKAETNGKIISLTVKEFDLLYFLCQHHGQVFSREQLLEK
HHHCCCHHCCCCCCEEECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
VWGYDYAGSTRTVDTHVKTMRLKLGESGNCIQTVWGVGYKFEV
HCCCCCCCCCCCHHHHHEEEEEECCCCCCHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]