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The map label for this gene is dapA [H]

Identifier: 152974773

GI number: 152974773

Start: 1085032

End: 1085958

Strand: Direct

Name: dapA [H]

Synonym: Bcer98_0964

Alternate gene names: 152974773

Gene position: 1085032-1085958 (Clockwise)

Preceding gene: 152974771

Following gene: 152974774

Centisome position: 26.55

GC content: 39.81

Gene sequence:

>927_bases
ATGGATAAATTCGCAGAAGCAAAGAAAAAATTGAGAGGTTCGATCGCCCCAATTATTACACCATTTGACGAGAGCGGTGC
AATTGATTTTCAAACATTTGAAAACTTAATTCATTGGCATATTGAAAGCGGGAGCCATGGTATTTCTGTTACAGGTACAA
CGGGCGAGCCAAGCTCTTTAAAGGTCGAGGAACGTGTAAAGGTAATGGAAACGGCGGCAAAGGCAATTAATGGGCGAGTT
CCTTTCGCACCGGGGACGGGGTCTACCAATCATGAAGAAACCTTGTATTTGACAAAAAAGGCACAAGAAATTGGAGCGGA
TGCAGCGCTTGTTATAGTGCCTTATTATAATAAGCCATCGCAGCACGCATTGTACAAACATTTTAAAACTGTCGCGGATT
CTGTTGATATTCCGATTATTATTTATAACATCCCAGGAAGAACAGCTGTCAATTTACAAGTGGAAACGATTGCGAAGTTA
AATCAAGATTGTCCCAATATTATTGGAATAAAAGAGTCAAATAAAGATTTTGAACATATTAATCGTGTTCTTCTGCATTG
TGGAAGAGATTTTCTCTTGTTCTCCGGCATTGAATTGCTTTGTTATCCAATGTTAGCAATTGGTGGCGCGGGGCATATTA
GTGCTACTGCGAACGTTGCTCCAAAGCAAGTTGCAGAAGTCTATAATGCGTGGAATGAAGGAGACATAAAACGTGCATTA
ACTCTTCATTATGAGCTTATGCCACTCAATGATGTGTTATTTAAGGATACAAATCCAGCTCCTGTAAAAGCAGCGCTCGG
TATGATGGGGAAAATTAAGCCGGTACTTCGTTTACCAATGGATGTTCCATCACAAGAATTGCAAGATGAAATTCGGGACG
TCTTAAAGAACTATGTAGAATTACCAGAAAGCATTGTATCTAGATAA

Upstream 100 bases:

>100_bases
AGAGTAATAATGTAATGAATTTTCTGATTAATTAGAAATTTGAAAGTGAGGAACTGTGCAATGCGTAAAGAAGTAGAAAT
GAAAAAGGAGAGACGAAAGA

Downstream 100 bases:

>100_bases
GGACATAGCCCCTTTAAAGTCATACAGATTTTAAGGGGCATCATTCAAAAAATTGTAGGAGGGAAGAATGTGCATATAGA
AGCGAAGGATATACAAAAGG

Product: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDKFAEAKKKLRGSIAPIITPFDESGAIDFQTFENLIHWHIESGSHGISVTGTTGEPSSLKVEERVKVMETAAKAINGRV
PFAPGTGSTNHEETLYLTKKAQEIGADAALVIVPYYNKPSQHALYKHFKTVADSVDIPIIIYNIPGRTAVNLQVETIAKL
NQDCPNIIGIKESNKDFEHINRVLLHCGRDFLLFSGIELLCYPMLAIGGAGHISATANVAPKQVAEVYNAWNEGDIKRAL
TLHYELMPLNDVLFKDTNPAPVKAALGMMGKIKPVLRLPMDVPSQELQDEIRDVLKNYVELPESIVSR

Sequences:

>Translated_308_residues
MDKFAEAKKKLRGSIAPIITPFDESGAIDFQTFENLIHWHIESGSHGISVTGTTGEPSSLKVEERVKVMETAAKAINGRV
PFAPGTGSTNHEETLYLTKKAQEIGADAALVIVPYYNKPSQHALYKHFKTVADSVDIPIIIYNIPGRTAVNLQVETIAKL
NQDCPNIIGIKESNKDFEHINRVLLHCGRDFLLFSGIELLCYPMLAIGGAGHISATANVAPKQVAEVYNAWNEGDIKRAL
TLHYELMPLNDVLFKDTNPAPVKAALGMMGKIKPVLRLPMDVPSQELQDEIRDVLKNYVELPESIVSR
>Mature_308_residues
MDKFAEAKKKLRGSIAPIITPFDESGAIDFQTFENLIHWHIESGSHGISVTGTTGEPSSLKVEERVKVMETAAKAINGRV
PFAPGTGSTNHEETLYLTKKAQEIGADAALVIVPYYNKPSQHALYKHFKTVADSVDIPIIIYNIPGRTAVNLQVETIAKL
NQDCPNIIGIKESNKDFEHINRVLLHCGRDFLLFSGIELLCYPMLAIGGAGHISATANVAPKQVAEVYNAWNEGDIKRAL
TLHYELMPLNDVLFKDTNPAPVKAALGMMGKIKPVLRLPMDVPSQELQDEIRDVLKNYVELPESIVSR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=293, Percent_Identity=27.9863481228669, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI13540533, Length=299, Percent_Identity=29.0969899665552, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788823, Length=286, Percent_Identity=37.4125874125874, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786463, Length=249, Percent_Identity=35.3413654618474, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87082415, Length=245, Percent_Identity=33.469387755102, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789620, Length=272, Percent_Identity=28.3088235294118, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33937; Mature: 33937

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFAEAKKKLRGSIAPIITPFDESGAIDFQTFENLIHWHIESGSHGISVTGTTGEPSSL
CCHHHHHHHHHCCCCCCEEECCCCCCCEEHHHHHHHHEEEECCCCCCEEEEECCCCCCCC
KVEERVKVMETAAKAINGRVPFAPGTGSTNHEETLYLTKKAQEIGADAALVIVPYYNKPS
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCEEEEEEECCCCCC
QHALYKHFKTVADSVDIPIIIYNIPGRTAVNLQVETIAKLNQDCPNIIGIKESNKDFEHI
HHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHCCCCCCEEECCCCCCHHHHH
NRVLLHCGRDFLLFSGIELLCYPMLAIGGAGHISATANVAPKQVAEVYNAWNEGDIKRAL
HHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHEEE
TLHYELMPLNDVLFKDTNPAPVKAALGMMGKIKPVLRLPMDVPSQELQDEIRDVLKNYVE
EEEEEEEECCHHEECCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHH
LPESIVSR
CHHHHHCC
>Mature Secondary Structure
MDKFAEAKKKLRGSIAPIITPFDESGAIDFQTFENLIHWHIESGSHGISVTGTTGEPSSL
CCHHHHHHHHHCCCCCCEEECCCCCCCEEHHHHHHHHEEEECCCCCCEEEEECCCCCCCC
KVEERVKVMETAAKAINGRVPFAPGTGSTNHEETLYLTKKAQEIGADAALVIVPYYNKPS
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCEEEEEEECCCCCC
QHALYKHFKTVADSVDIPIIIYNIPGRTAVNLQVETIAKLNQDCPNIIGIKESNKDFEHI
HHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHCCCCCCEEECCCCCCHHHHH
NRVLLHCGRDFLLFSGIELLCYPMLAIGGAGHISATANVAPKQVAEVYNAWNEGDIKRAL
HHHHHHCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHEEE
TLHYELMPLNDVLFKDTNPAPVKAALGMMGKIKPVLRLPMDVPSQELQDEIRDVLKNYVE
EEEEEEEECCHHEECCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHH
LPESIVSR
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA