BacMap

Definition	Bacillus cereus subsp. cytotoxis NVH 391-98, complete genome.
Accession	NC_009674
Length	4,087,024

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The map label for this gene is hpcC [H]

Identifier: 152974774

GI number: 152974774

Start: 1086028

End: 1087551

Strand: Direct

Name: hpcC [H]

Synonym: Bcer98_0965

Alternate gene names: 152974774

Gene position: 1086028-1087551 (Clockwise)

Preceding gene: 152974773

Following gene: 152974775

Centisome position: 26.57

GC content: 40.22

Gene sequence:

>1524_bases
GTGCATATAGAAGCGAAGGATATACAAAAGGATAAATCTTATGAGCAAATAGAACATGTAGATTTATATATTGATGGAGA
ATTTAGAAAAGCGCAGTCTGGAAAAGTATTTGTAAATATGAATCCGTTTACAAATAAGGAGATTAATCGAGTAGCTGAAG
GGGATAGAGTTGATATCAATCTGGCAGTTGCTGCAGCGAAATTCGCTTTTGAAAAAGGGCCATGGGGCAAGATGAAAGTA
GAAGAGAGAATGCGATATATCAATCGAATTGCGGACTTAATTGATGAGGAAATAGAAGAAATCGCGTATTTGGAAGCACT
AGATACGGGGCTTCCTATTAGTCAAACGAGAAAAATGACATCGCGTGCAGCAGAAAACTTTCGTTTCTATGCAAGAATGG
TGCAAACGAAATTACACGGTGAAGCATATCCAGTCAACAAAGAATTTATTAATTACACTGTCTATCATCCAATTGGGGTT
GTTGGCCTTATCACCCCATGGAATGCACCGTTCATGTTAGAAACTTGGAAAGTAGCTCCGGCATTAGCTACCGGGAATAC
AGTTGTTTTAAAGCCGGCTGAATTATCTCCTTTAACGGCTAACAAACTGGCTGAAATAATTCATAAAGCAGAAGTGCCAA
AGGGCGTCTTTAACGTCGTTCATGGCTTTGGGGAAACAGCGGGTGCCTCTCTTGTCGCTCATAAAGATGTGAAAGCAATA
TCGTTCACAGGTGAAACAACGACAGGTTCGATCATTATGAAAAATGCGGCTGATACGCTAAAGAAAACTTCAATGGAACT
AGGTGGTAAATCTCCTCTTATCGTCTTTGAAGATGCGGATTTAGAGCGCGCTTTAGATGCGGCTGTGTGGGGCATTTTCT
CATTTAATGGAGAACGCTGTACCGCTAATTCTCGCTTGTTACTGCACAAAAATATTAAAGATCAATTTATTGAAAAATTA
AAAGAACGTGTAGGCTACATTACAATCGGCGATCCGATGGACTCTAAGACAGAACTTGGTCCGTTAATTGAAAAACAGCA
TTTTCAAAAGGTACAAAAGTATATTGAAATCGCGAAAGAAGAAGGATGTGAAGTGATACAAGGAGTTGTTCCCGAATCGG
TGCAAGCGGGTAACTTTGTGCCGCCAACTTTATTATTACATGCAAAAAATGAGATGCGAGTATGCCAAGAAGAAATATTT
GGTCCTGTTATGGCTGTTATGGAATTTGAAACGGAAGAAGAAGCGATTGCAATTGCTAATGATGTAAGGTACGGACTTGC
TGGTTATGTTTGGACAAATGATATGAAGAGAGGTCATCGACTTGCGCAGTCCATTGAAGCGGGCATGTTATGGGTGAACG
CTCAAAATGTACGCGATCTTCGAATTCCGTTTGGTGGAGCAAAAGATAGCGGGATTGGAAGAGAAGGTGGACACTATGCC
ATTTTCGAGTTTTATACGGAACCAAAGGTCATTCATGTTGCAATCGGAGATCATCATATTCCGAAGTTTGGCACAAAGAA
ATAA

Upstream 100 bases:

>100_bases
AGAATTACCAGAAAGCATTGTATCTAGATAAGGACATAGCCCCTTTAAAGTCATACAGATTTTAAGGGGCATCATTCAAA
AAATTGTAGGAGGGAAGAAT

Downstream 100 bases:

>100_bases
CAAGCTGCAGATGAAAGTATAAAAACAATAGTTTCATGAAAGGGGAGAGTGAAATGCCAGCAAAAACAGGAAAAGAATAT
ATCGAAAGAGTAGATCAAGC

Product: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: CHMS dehydrogenase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MHIEAKDIQKDKSYEQIEHVDLYIDGEFRKAQSGKVFVNMNPFTNKEINRVAEGDRVDINLAVAAAKFAFEKGPWGKMKV
EERMRYINRIADLIDEEIEEIAYLEALDTGLPISQTRKMTSRAAENFRFYARMVQTKLHGEAYPVNKEFINYTVYHPIGV
VGLITPWNAPFMLETWKVAPALATGNTVVLKPAELSPLTANKLAEIIHKAEVPKGVFNVVHGFGETAGASLVAHKDVKAI
SFTGETTTGSIIMKNAADTLKKTSMELGGKSPLIVFEDADLERALDAAVWGIFSFNGERCTANSRLLLHKNIKDQFIEKL
KERVGYITIGDPMDSKTELGPLIEKQHFQKVQKYIEIAKEEGCEVIQGVVPESVQAGNFVPPTLLLHAKNEMRVCQEEIF
GPVMAVMEFETEEEAIAIANDVRYGLAGYVWTNDMKRGHRLAQSIEAGMLWVNAQNVRDLRIPFGGAKDSGIGREGGHYA
IFEFYTEPKVIHVAIGDHHIPKFGTKK

Sequences:

>Translated_507_residues
MHIEAKDIQKDKSYEQIEHVDLYIDGEFRKAQSGKVFVNMNPFTNKEINRVAEGDRVDINLAVAAAKFAFEKGPWGKMKV
EERMRYINRIADLIDEEIEEIAYLEALDTGLPISQTRKMTSRAAENFRFYARMVQTKLHGEAYPVNKEFINYTVYHPIGV
VGLITPWNAPFMLETWKVAPALATGNTVVLKPAELSPLTANKLAEIIHKAEVPKGVFNVVHGFGETAGASLVAHKDVKAI
SFTGETTTGSIIMKNAADTLKKTSMELGGKSPLIVFEDADLERALDAAVWGIFSFNGERCTANSRLLLHKNIKDQFIEKL
KERVGYITIGDPMDSKTELGPLIEKQHFQKVQKYIEIAKEEGCEVIQGVVPESVQAGNFVPPTLLLHAKNEMRVCQEEIF
GPVMAVMEFETEEEAIAIANDVRYGLAGYVWTNDMKRGHRLAQSIEAGMLWVNAQNVRDLRIPFGGAKDSGIGREGGHYA
IFEFYTEPKVIHVAIGDHHIPKFGTKK
>Mature_507_residues
MHIEAKDIQKDKSYEQIEHVDLYIDGEFRKAQSGKVFVNMNPFTNKEINRVAEGDRVDINLAVAAAKFAFEKGPWGKMKV
EERMRYINRIADLIDEEIEEIAYLEALDTGLPISQTRKMTSRAAENFRFYARMVQTKLHGEAYPVNKEFINYTVYHPIGV
VGLITPWNAPFMLETWKVAPALATGNTVVLKPAELSPLTANKLAEIIHKAEVPKGVFNVVHGFGETAGASLVAHKDVKAI
SFTGETTTGSIIMKNAADTLKKTSMELGGKSPLIVFEDADLERALDAAVWGIFSFNGERCTANSRLLLHKNIKDQFIEKL
KERVGYITIGDPMDSKTELGPLIEKQHFQKVQKYIEIAKEEGCEVIQGVVPESVQAGNFVPPTLLLHAKNEMRVCQEEIF
GPVMAVMEFETEEEAIAIANDVRYGLAGYVWTNDMKRGHRLAQSIEAGMLWVNAQNVRDLRIPFGGAKDSGIGREGGHYA
IFEFYTEPKVIHVAIGDHHIPKFGTKK

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=478, Percent_Identity=41.6317991631799, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI25777730, Length=482, Percent_Identity=39.8340248962656, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI153266822, Length=487, Percent_Identity=38.8090349075975, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI25777724, Length=483, Percent_Identity=38.3022774327122, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI12007648, Length=481, Percent_Identity=40.5405405405405, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI21361176, Length=482, Percent_Identity=39.2116182572614, Blast_Score=358, Evalue=9e-99,
Organism=Homo sapiens, GI238814322, Length=472, Percent_Identity=39.4067796610169, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI115387104, Length=461, Percent_Identity=38.3947939262473, Blast_Score=328, Evalue=7e-90,
Organism=Homo sapiens, GI25777728, Length=420, Percent_Identity=38.5714285714286, Blast_Score=318, Evalue=8e-87,
Organism=Homo sapiens, GI21614513, Length=473, Percent_Identity=39.1120507399577, Blast_Score=317, Evalue=2e-86,
Organism=Homo sapiens, GI25777726, Length=482, Percent_Identity=35.6846473029046, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI25952152, Length=475, Percent_Identity=36.8421052631579, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI4507229, Length=472, Percent_Identity=34.1101694915254, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI25777721, Length=485, Percent_Identity=33.1958762886598, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI301500698, Length=282, Percent_Identity=41.4893617021277, Blast_Score=228, Evalue=8e-60,
Organism=Homo sapiens, GI11095441, Length=482, Percent_Identity=30.4979253112033, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI310128093, Length=459, Percent_Identity=28.1045751633987, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI188035924, Length=459, Percent_Identity=27.8867102396514, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI310128103, Length=459, Percent_Identity=27.8867102396514, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI223972651, Length=465, Percent_Identity=26.6666666666667, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI310128091, Length=337, Percent_Identity=30.8605341246291, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI206597441, Length=337, Percent_Identity=34.1246290801187, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI206597439, Length=337, Percent_Identity=34.1246290801187, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI22907049, Length=337, Percent_Identity=34.1246290801187, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4557303, Length=350, Percent_Identity=30.2857142857143, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI73466520, Length=350, Percent_Identity=30.2857142857143, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI73695881, Length=330, Percent_Identity=29.6969696969697, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI73695879, Length=330, Percent_Identity=29.6969696969697, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4502043, Length=330, Percent_Identity=30, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI238814371, Length=330, Percent_Identity=30, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI71773324, Length=330, Percent_Identity=30, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=29.6636085626911, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI238859541, Length=483, Percent_Identity=26.2939958592132, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI310128097, Length=247, Percent_Identity=32.7935222672065, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI25777736, Length=483, Percent_Identity=26.2939958592132, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI25777734, Length=483, Percent_Identity=26.2939958592132, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI223972653, Length=465, Percent_Identity=24.3010752688172, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310128095, Length=306, Percent_Identity=29.7385620915033, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310128087, Length=459, Percent_Identity=23.3115468409586, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1787558, Length=489, Percent_Identity=39.0593047034765, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI87082295, Length=495, Percent_Identity=37.5757575757576, Blast_Score=327, Evalue=7e-91,
Organism=Escherichia coli, GI1786504, Length=477, Percent_Identity=40.041928721174, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI87081896, Length=462, Percent_Identity=36.7965367965368, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1789015, Length=475, Percent_Identity=35.5789473684211, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1787715, Length=472, Percent_Identity=38.771186440678, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1787684, Length=475, Percent_Identity=33.6842105263158, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI87081926, Length=450, Percent_Identity=29.7777777777778, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1788042, Length=469, Percent_Identity=28.3582089552239, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787250, Length=418, Percent_Identity=29.6650717703349, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1787653, Length=396, Percent_Identity=25.2525252525253, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562198, Length=477, Percent_Identity=43.6058700209644, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI25144435, Length=481, Percent_Identity=40.956340956341, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI133930964, Length=473, Percent_Identity=40.8033826638478, Blast_Score=344, Evalue=6e-95,
Organism=Caenorhabditis elegans, GI32564736, Length=420, Percent_Identity=40.7142857142857, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17551164, Length=495, Percent_Identity=38.5858585858586, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI25143876, Length=478, Percent_Identity=37.4476987447699, Blast_Score=313, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI25143874, Length=478, Percent_Identity=37.4476987447699, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI71995606, Length=485, Percent_Identity=36.4948453608247, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17534119, Length=505, Percent_Identity=33.4653465346535, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=36.3420427553444, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI115534176, Length=459, Percent_Identity=32.0261437908497, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI71986308, Length=487, Percent_Identity=29.7741273100616, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI25146391, Length=338, Percent_Identity=30.7692307692308, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25146394, Length=338, Percent_Identity=30.7692307692308, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI32566756, Length=338, Percent_Identity=30.7692307692308, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17564084, Length=343, Percent_Identity=30.9037900874636, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17534447, Length=459, Percent_Identity=25.7080610021786, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI115532534, Length=364, Percent_Identity=27.1978021978022, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=393, Percent_Identity=26.2086513994911, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=280, Percent_Identity=24.2857142857143, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=483, Percent_Identity=39.3374741200828, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6323822, Length=486, Percent_Identity=38.0658436213992, Blast_Score=343, Evalue=3e-95,
Organism=Saccharomyces cerevisiae, GI6324950, Length=463, Percent_Identity=39.3088552915767, Blast_Score=338, Evalue=9e-94,
Organism=Saccharomyces cerevisiae, GI6323821, Length=482, Percent_Identity=38.7966804979253, Blast_Score=335, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6325196, Length=486, Percent_Identity=35.59670781893, Blast_Score=323, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6319478, Length=473, Percent_Identity=35.7293868921776, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6321828, Length=463, Percent_Identity=25.4859611231102, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=431, Percent_Identity=26.6821345707657, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323757, Length=317, Percent_Identity=28.391167192429, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129399, Length=495, Percent_Identity=39.3939393939394, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24650465, Length=480, Percent_Identity=40.2083333333333, Blast_Score=358, Evalue=6e-99,
Organism=Drosophila melanogaster, GI24585660, Length=480, Percent_Identity=37.5, Blast_Score=321, Evalue=9e-88,
Organism=Drosophila melanogaster, GI281362580, Length=466, Percent_Identity=34.9785407725322, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI62472918, Length=466, Percent_Identity=34.9785407725322, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI62472926, Length=466, Percent_Identity=34.9785407725322, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI62472936, Length=466, Percent_Identity=34.9785407725322, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI21356737, Length=466, Percent_Identity=34.9785407725322, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24638876, Length=496, Percent_Identity=26.4112903225806, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24638878, Length=495, Percent_Identity=26.2626262626263, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24666674, Length=468, Percent_Identity=27.1367521367521, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281360303, Length=449, Percent_Identity=29.6213808463252, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360301, Length=449, Percent_Identity=29.3986636971047, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI45552499, Length=351, Percent_Identity=31.6239316239316, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360299, Length=351, Percent_Identity=31.3390313390313, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281360297, Length=351, Percent_Identity=31.3390313390313, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281360295, Length=351, Percent_Identity=31.3390313390313, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24586250, Length=351, Percent_Identity=31.3390313390313, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24668425, Length=471, Percent_Identity=25.4777070063694, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24668417, Length=471, Percent_Identity=25.4777070063694, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24668413, Length=471, Percent_Identity=25.4777070063694, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574525, Length=465, Percent_Identity=24.7311827956989, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571802, Length=517, Percent_Identity=21.6634429400387, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571800, Length=517, Percent_Identity=21.6634429400387, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571798, Length=517, Percent_Identity=21.6634429400387, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571796, Length=517, Percent_Identity=21.6634429400387, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571794, Length=517, Percent_Identity=21.6634429400387, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571806, Length=517, Percent_Identity=21.6634429400387, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360293, Length=269, Percent_Identity=30.4832713754647, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR011985 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 56667; Mature: 56667

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIEAKDIQKDKSYEQIEHVDLYIDGEFRKAQSGKVFVNMNPFTNKEINRVAEGDRVDIN
CCCCHHHHHCCCCHHHHEEEEEEECCCEEECCCCEEEEEECCCCCHHHHHHCCCCEEEEE
LAVAAAKFAFEKGPWGKMKVEERMRYINRIADLIDEEIEEIAYLEALDTGLPISQTRKMT
EEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SRAAENFRFYARMVQTKLHGEAYPVNKEFINYTVYHPIGVVGLITPWNAPFMLETWKVAP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCEEEEECCCCCCEEEEEEEECE
ALATGNTVVLKPAELSPLTANKLAEIIHKAEVPKGVFNVVHGFGETAGASLVAHKDVKAI
EEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCEEE
SFTGETTTGSIIMKNAADTLKKTSMELGGKSPLIVFEDADLERALDAAVWGIFSFNGERC
EECCCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHEEECCCEE
TANSRLLLHKNIKDQFIEKLKERVGYITIGDPMDSKTELGPLIEKQHFQKVQKYIEIAKE
CCCCEEEEECCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGCEVIQGVVPESVQAGNFVPPTLLLHAKNEMRVCQEEIFGPVMAVMEFETEEEAIAIAN
CCHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
DVRYGLAGYVWTNDMKRGHRLAQSIEAGMLWVNAQNVRDLRIPFGGAKDSGIGREGGHYA
HHHHCCEEEEEECCHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCCCCCCCCCCCCCEE
IFEFYTEPKVIHVAIGDHHIPKFGTKK
EEEEECCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MHIEAKDIQKDKSYEQIEHVDLYIDGEFRKAQSGKVFVNMNPFTNKEINRVAEGDRVDIN
CCCCHHHHHCCCCHHHHEEEEEEECCCEEECCCCEEEEEECCCCCHHHHHHCCCCEEEEE
LAVAAAKFAFEKGPWGKMKVEERMRYINRIADLIDEEIEEIAYLEALDTGLPISQTRKMT
EEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SRAAENFRFYARMVQTKLHGEAYPVNKEFINYTVYHPIGVVGLITPWNAPFMLETWKVAP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCEEEEECCCCCCEEEEEEEECE
ALATGNTVVLKPAELSPLTANKLAEIIHKAEVPKGVFNVVHGFGETAGASLVAHKDVKAI
EEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEECCCEEE
SFTGETTTGSIIMKNAADTLKKTSMELGGKSPLIVFEDADLERALDAAVWGIFSFNGERC
EECCCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHEEECCCEE
TANSRLLLHKNIKDQFIEKLKERVGYITIGDPMDSKTELGPLIEKQHFQKVQKYIEIAKE
CCCCEEEEECCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGCEVIQGVVPESVQAGNFVPPTLLLHAKNEMRVCQEEIFGPVMAVMEFETEEEAIAIAN
CCHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
DVRYGLAGYVWTNDMKRGHRLAQSIEAGMLWVNAQNVRDLRIPFGGAKDSGIGREGGHYA
HHHHCCEEEEEECCHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCCCCCCCCCCCCCEE
IFEFYTEPKVIHVAIGDHHIPKFGTKK
EEEEECCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]