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The map label for this gene is rfbC [C]

Identifier: 152974748

GI number: 152974748

Start: 1053267

End: 1053815

Strand: Direct

Name: rfbC [C]

Synonym: Bcer98_0938

Alternate gene names: 152974748

Gene position: 1053267-1053815 (Clockwise)

Preceding gene: 152974747

Following gene: 152974749

Centisome position: 25.77

GC content: 35.15

Gene sequence:

>549_bases
ATGGAAATAGTTGAAACACATTTTCAGCATGCTTTATTATTACAACCTCGTTTATTTGAAGATCATCGTGGTTTTTTTAC
AGAAAGTTATAATTGGAAAGAGTTTCAAAAATTAGGCGTTTCTTATTCGTTCATTCAAGATAATCTTTCATTTTCAGCGA
AGGCCGGCACAGTGCGTGGTTTGCATTTTCAGAAAGAGCCGAAAGCACAAACGAAATTAATTCAAGTATTAAAAGGGGCA
ATCTATGATGTTATTGTGGATTTACGCGTTTCCTCTCCAACATATAAAGAGTGGAAAGGCTTTATATTAAGTGAAGAAAA
TCATAGACAGCTTCTTGTGCCAAAAGGTTTTGCTCATGGATTTTGTACGCTCGTGCCAAATACACTCGTCATGTATAAAG
TAGATGAATATTATAGTTCAGATCATGATGATGGATTATATTGGAATGATGAAAGCTTGGCGATTACATGGCCGGTCAGT
GAACCGATTCTTTCAGAAAAAGATAAAGCGTTGCCTACATTTGACCAATATCATGATTGTTTTAAGTAG

Upstream 100 bases:

>100_bases
GGTGGACAGACGCAGGAACACATGCATCATTGCAGAGAGCAAATGCATTAGCGTGTCATTTAGATTTTGGTCAACAATTT
AATGGGGAATAGGTGGGTAT

Downstream 100 bases:

>100_bases
AGGTGTTGGATATGAATATATTCGTAACTGGTGGAGCAGGTTTTATTGGAAGTAACTTTATTCGTTATATATTACGGACG
CATCAGACATATCGTATCAT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MEIVETHFQHALLLQPRLFEDHRGFFTESYNWKEFQKLGVSYSFIQDNLSFSAKAGTVRGLHFQKEPKAQTKLIQVLKGA
IYDVIVDLRVSSPTYKEWKGFILSEENHRQLLVPKGFAHGFCTLVPNTLVMYKVDEYYSSDHDDGLYWNDESLAITWPVS
EPILSEKDKALPTFDQYHDCFK

Sequences:

>Translated_182_residues
MEIVETHFQHALLLQPRLFEDHRGFFTESYNWKEFQKLGVSYSFIQDNLSFSAKAGTVRGLHFQKEPKAQTKLIQVLKGA
IYDVIVDLRVSSPTYKEWKGFILSEENHRQLLVPKGFAHGFCTLVPNTLVMYKVDEYYSSDHDDGLYWNDESLAITWPVS
EPILSEKDKALPTFDQYHDCFK
>Mature_182_residues
MEIVETHFQHALLLQPRLFEDHRGFFTESYNWKEFQKLGVSYSFIQDNLSFSAKAGTVRGLHFQKEPKAQTKLIQVLKGA
IYDVIVDLRVSSPTYKEWKGFILSEENHRQLLVPKGFAHGFCTLVPNTLVMYKVDEYYSSDHDDGLYWNDESLAITWPVS
EPILSEKDKALPTFDQYHDCFK

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=178, Percent_Identity=46.6292134831461, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17550412, Length=168, Percent_Identity=39.2857142857143, Blast_Score=114, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21215; Mature: 21215

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVETHFQHALLLQPRLFEDHRGFFTESYNWKEFQKLGVSYSFIQDNLSFSAKAGTVRG
CCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHCCCCEEHHCCCCEECCCCEEEC
LHFQKEPKAQTKLIQVLKGAIYDVIVDLRVSSPTYKEWKGFILSEENHRQLLVPKGFAHG
CCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHCCEEECCCCCCEEEEECCCCCE
FCTLVPNTLVMYKVDEYYSSDHDDGLYWNDESLAITWPVSEPILSEKDKALPTFDQYHDC
EEEECCCEEEEEEEHHHHCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
FK
CC
>Mature Secondary Structure
MEIVETHFQHALLLQPRLFEDHRGFFTESYNWKEFQKLGVSYSFIQDNLSFSAKAGTVRG
CCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHCCCCEEHHCCCCEECCCCEEEC
LHFQKEPKAQTKLIQVLKGAIYDVIVDLRVSSPTYKEWKGFILSEENHRQLLVPKGFAHG
CCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHCCEEECCCCCCEEEEECCCCCE
FCTLVPNTLVMYKVDEYYSSDHDDGLYWNDESLAITWPVSEPILSEKDKALPTFDQYHDC
EEEECCCEEEEEEEHHHHCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
FK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]