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The map label for this gene is malZ [C]

Identifier: 152974688

GI number: 152974688

Start: 993840

End: 995162

Strand: Direct

Name: malZ [C]

Synonym: Bcer98_0875

Alternate gene names: 152974688

Gene position: 993840-995162 (Clockwise)

Preceding gene: 152974687

Following gene: 152974690

Centisome position: 24.32

GC content: 35.22

Gene sequence:

>1323_bases
GTGAAAAGAATATGGCGAGGTACATGCACTTTGATTTGTATAACAATTTGTCTCATCATGCCTATACAACAAAGTTTGGC
AAAAGAAAAAAGAGAATGGCAAGATGAAGTGGTATATTCCATTATGATTGACCGCTTTAATAATGGAGATGCGAAAAACG
ATAGCGGTCTGAATACGGAGAATTTAGAGGATTATCAAGGCGGGGATATCTCAGGAATTATAAAGAGGCTTGATTACATA
AAAGATATGGGATTTACTGCAATTATGCTTTCACCTCTTTCGGAAAGTAAAAAATATGATGGAACAGGTGTGGGGAATCT
GCGACAGGTAAATGAACATTTTGGTTCATTGCAAGATGTAAGGAAGCTTGTGCAGGAAGCTCATAAAAAGGAGATGAAAG
TGATATTTCAATTTATCGCTGGAGAAGAAGATTCGCGACAAATGGTAGATGTAGTAAAATGGTGGATGCAAGAAGTAAAT
ATAGATGGAAGTTATTTCATACATAGTGAAAAGTTGTCCAATGATTCGTTACATGACATGAAGAAACAACTAAAAGATAT
AAAAAAAGATTTTGTAGTTCTAACAGATGAAAAGGAAAGTGCACATAACGATTACTATAAAGCAATAACGAATGCATTTT
CAAAAACAGATCGCTCCATTCAGCCATTATATCATGCAAGTTTAATAGAGGCGGAGCAAGTTATGAATACATATATTGAT
CATCAAAATACGAAAAGGTTTGTGCGTCTTGTAAAAGAAAATGGCTATTATCCGCCAGCTCGTTTAAAGTTAGCACTTGC
TTATTTATATACATCTCCAGGGCTACCAATTGTCTATTATGGTACCGAAATCGCGCTAGATGGCGGAGACGTTCCAGATA
ATCGGCGGTTAATGGACTTTAAAACGGATGAAAAGTTTTTGCGATATATAACAAAACTAGGAGAATTAAGGAAAGAACTG
CCGTCTTTACGCCGCGGTACCTTTGAACTATTACATGATGAAGAGGGAATGAGTATACTAAAAAGAACATATAAAGATGA
AGTTACTATTATTGCTTTAAATAATACGAAAGTAACAAAAAAAGTTGCGTTGCCGGCAAATATAGTAGGAGAAAAGCGAC
AATTAAGAGGGCTGTTAGAAGATGAAATCATAAGGGAAGAAGGTGGGAAGTATTATCTTGTATTGAAGCGGGAAGAAGCA
AATATATATAAAGCTGGTGAACAAACAAGTATCAATTGGGTATTTGTATCTATGATTGTACTTGTAAATCTTGCATTTAT
CGTGTTTTTAATTGCAGTCAAAAAGCGTGGGAAACAGGTATGA

Upstream 100 bases:

>100_bases
AAATCTCTCGTGTAAGAGGAACTGTGCAAGATGTGATATGCGTTTTTGAAAGAAAATTGATATACTATTCTTACAATTAA
GATAAGGTTGGGGGATTTGT

Downstream 100 bases:

>100_bases
ATAAGAAAACATCCTCCGCATGCGGAGGATGTTTTCTTATTAACGATAGTTAATGAATTGTACATCAATTGGTAAATCAG
CGCTGCGAATTGCTGCGATT

Product: alpha amylase catalytic region

Products: NA

Alternate protein names: Beta-amylase; Alpha-amylase [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKRIWRGTCTLICITICLIMPIQQSLAKEKREWQDEVVYSIMIDRFNNGDAKNDSGLNTENLEDYQGGDISGIIKRLDYI
KDMGFTAIMLSPLSESKKYDGTGVGNLRQVNEHFGSLQDVRKLVQEAHKKEMKVIFQFIAGEEDSRQMVDVVKWWMQEVN
IDGSYFIHSEKLSNDSLHDMKKQLKDIKKDFVVLTDEKESAHNDYYKAITNAFSKTDRSIQPLYHASLIEAEQVMNTYID
HQNTKRFVRLVKENGYYPPARLKLALAYLYTSPGLPIVYYGTEIALDGGDVPDNRRLMDFKTDEKFLRYITKLGELRKEL
PSLRRGTFELLHDEEGMSILKRTYKDEVTIIALNNTKVTKKVALPANIVGEKRQLRGLLEDEIIREEGGKYYLVLKREEA
NIYKAGEQTSINWVFVSMIVLVNLAFIVFLIAVKKRGKQV

Sequences:

>Translated_440_residues
MKRIWRGTCTLICITICLIMPIQQSLAKEKREWQDEVVYSIMIDRFNNGDAKNDSGLNTENLEDYQGGDISGIIKRLDYI
KDMGFTAIMLSPLSESKKYDGTGVGNLRQVNEHFGSLQDVRKLVQEAHKKEMKVIFQFIAGEEDSRQMVDVVKWWMQEVN
IDGSYFIHSEKLSNDSLHDMKKQLKDIKKDFVVLTDEKESAHNDYYKAITNAFSKTDRSIQPLYHASLIEAEQVMNTYID
HQNTKRFVRLVKENGYYPPARLKLALAYLYTSPGLPIVYYGTEIALDGGDVPDNRRLMDFKTDEKFLRYITKLGELRKEL
PSLRRGTFELLHDEEGMSILKRTYKDEVTIIALNNTKVTKKVALPANIVGEKRQLRGLLEDEIIREEGGKYYLVLKREEA
NIYKAGEQTSINWVFVSMIVLVNLAFIVFLIAVKKRGKQV
>Mature_440_residues
MKRIWRGTCTLICITICLIMPIQQSLAKEKREWQDEVVYSIMIDRFNNGDAKNDSGLNTENLEDYQGGDISGIIKRLDYI
KDMGFTAIMLSPLSESKKYDGTGVGNLRQVNEHFGSLQDVRKLVQEAHKKEMKVIFQFIAGEEDSRQMVDVVKWWMQEVN
IDGSYFIHSEKLSNDSLHDMKKQLKDIKKDFVVLTDEKESAHNDYYKAITNAFSKTDRSIQPLYHASLIEAEQVMNTYID
HQNTKRFVRLVKENGYYPPARLKLALAYLYTSPGLPIVYYGTEIALDGGDVPDNRRLMDFKTDEKFLRYITKLGELRKEL
PSLRRGTFELLHDEEGMSILKRTYKDEVTIIALNNTKVTKKVALPANIVGEKRQLRGLLEDEIIREEGGKYYLVLKREEA
NIYKAGEQTSINWVFVSMIVLVNLAFIVFLIAVKKRGKQV

Specific function: The precursor protein is proteolytically cleaved to produce multiform beta-amylases and a 48 kDa alpha-amylase after secretion [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI61744483, Length=264, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI61744479, Length=395, Percent_Identity=21.5189873417722, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI65506891, Length=395, Percent_Identity=21.5189873417722, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI61744481, Length=395, Percent_Identity=21.5189873417722, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI61744477, Length=395, Percent_Identity=21.5189873417722, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI61744475, Length=395, Percent_Identity=21.5189873417722, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786604, Length=170, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789995, Length=194, Percent_Identity=25.7731958762887, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583745, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006048
- InterPro:   IPR005085
- InterPro:   IPR008985
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR001554
- InterPro:   IPR018238
- InterPro:   IPR000125
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF03423 CBM_25; PF01373 Glyco_hydro_14 [H]

EC number: =3.2.1.2; =3.2.1.1 [H]

Molecular weight: Translated: 50795; Mature: 50795

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIWRGTCTLICITICLIMPIQQSLAKEKREWQDEVVYSIMIDRFNNGDAKNDSGLNTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NLEDYQGGDISGIIKRLDYIKDMGFTAIMLSPLSESKKYDGTGVGNLRQVNEHFGSLQDV
CCCCCCCCCHHHHHHHHHHHHHCCCHHEEECCHHHCCCCCCCCCCHHHHHHHHHCCHHHH
RKLVQEAHKKEMKVIFQFIAGEEDSRQMVDVVKWWMQEVNIDGSYFIHSEKLSNDSLHDM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHH
KKQLKDIKKDFVVLTDEKESAHNDYYKAITNAFSKTDRSIQPLYHASLIEAEQVMNTYID
HHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
HQNTKRFVRLVKENGYYPPARLKLALAYLYTSPGLPIVYYGTEIALDGGDVPDNRRLMDF
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCCEEECC
KTDEKFLRYITKLGELRKELPSLRRGTFELLHDEEGMSILKRTYKDEVTIIALNNTKVTK
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCEEH
KVALPANIVGEKRQLRGLLEDEIIREEGGKYYLVLKREEANIYKAGEQTSINWVFVSMIV
EEECCHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHH
LVNLAFIVFLIAVKKRGKQV
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRIWRGTCTLICITICLIMPIQQSLAKEKREWQDEVVYSIMIDRFNNGDAKNDSGLNTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NLEDYQGGDISGIIKRLDYIKDMGFTAIMLSPLSESKKYDGTGVGNLRQVNEHFGSLQDV
CCCCCCCCCHHHHHHHHHHHHHCCCHHEEECCHHHCCCCCCCCCCHHHHHHHHHCCHHHH
RKLVQEAHKKEMKVIFQFIAGEEDSRQMVDVVKWWMQEVNIDGSYFIHSEKLSNDSLHDM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHH
KKQLKDIKKDFVVLTDEKESAHNDYYKAITNAFSKTDRSIQPLYHASLIEAEQVMNTYID
HHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
HQNTKRFVRLVKENGYYPPARLKLALAYLYTSPGLPIVYYGTEIALDGGDVPDNRRLMDF
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCCEEECC
KTDEKFLRYITKLGELRKELPSLRRGTFELLHDEEGMSILKRTYKDEVTIIALNNTKVTK
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCEEH
KVALPANIVGEKRQLRGLLEDEIIREEGGKYYLVLKREEANIYKAGEQTSINWVFVSMIV
EEECCHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHH
LVNLAFIVFLIAVKKRGKQV
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2435707; 2464578; 2438660; 1827035 [H]