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The map label for this gene is tcyB [H]

Identifier: 152974512

GI number: 152974512

Start: 779358

End: 780056

Strand: Direct

Name: tcyB [H]

Synonym: Bcer98_0688

Alternate gene names: 152974512

Gene position: 779358-780056 (Clockwise)

Preceding gene: 152974511

Following gene: 152974513

Centisome position: 19.07

GC content: 36.91

Gene sequence:

>699_bases
ATGTATCTAAGTAATGTATTCACCCTAGATCGTTTCTCTACGTGGATGGATATTATGCAAGCTTCCTTCATGCCTATGCT
GAAGGAAGCCATTTTTACGACAATTCCATTGACAATTATAACATTTATCATCGGTCTCATTTTGGCGACTTTGACGGCAC
TTGCACGCATTTCAAATAGTCGTATATTACAATGGATTGCTCGTATCTATGTATCTATTATTCGCGGAACACCACTTCTT
GTACAATTGTTTCTTATTTTCTATGGTCTTCCAACTTTACAAATCGAAATTGATCCATATACAGCAGCAGTAATTGGATT
TTCATTAAACGTTGGTGCATATGCATCTGAAATTATTCGCGCTTCTATTTTGTCCATTCCGAAAGGACAATGGGAAGCAG
CTTACACAATGGGTATGACGTACACGCAAGCGTTAAAACGTATTATTTTACCGCAAGCGACGCGCGTATCCATTCCGCCG
CTTTCAAACACCTTTATTAGTTTAGTGAAGGATACATCACTTGCTTCCTTAATCTTAGTTACAGAGATGTTTCGAAAAGC
GCAGGAAATTGCAGCGATGAACTATGAGTTTTTAATTGTATATTTCGAAGCTGCACTTATGTATTGGGTGATTTGTTTCT
TATTATCCATTGTGCAACAAATATTAGAAAAACGTACGGAACGCTATATACTAAAATAA

Upstream 100 bases:

>100_bases
AAAGGCAGCGGTAAATTAGTACAAGAAGTAAATAAAGCGTTAGAAGATATGAAAAAAGATGGTACGTATGACAAAATAGC
GAAAAAATGGTTCGGTGAAA

Downstream 100 bases:

>100_bases
TCCTTTCATAAAAGGAGTTTTTATTTTTATGATTTCAATTCAACATTTACAAAAAAGTTTCGGTGAAAATACCGTACTAA
AGCATATAGATTTATCCGTT

Product: polar amino acid ABC transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MYLSNVFTLDRFSTWMDIMQASFMPMLKEAIFTTIPLTIITFIIGLILATLTALARISNSRILQWIARIYVSIIRGTPLL
VQLFLIFYGLPTLQIEIDPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTMGMTYTQALKRIILPQATRVSIPP
LSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAALMYWVICFLLSIVQQILEKRTERYILK

Sequences:

>Translated_232_residues
MYLSNVFTLDRFSTWMDIMQASFMPMLKEAIFTTIPLTIITFIIGLILATLTALARISNSRILQWIARIYVSIIRGTPLL
VQLFLIFYGLPTLQIEIDPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTMGMTYTQALKRIILPQATRVSIPP
LSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAALMYWVICFLLSIVQQILEKRTERYILK
>Mature_232_residues
MYLSNVFTLDRFSTWMDIMQASFMPMLKEAIFTTIPLTIITFIIGLILATLTALARISNSRILQWIARIYVSIIRGTPLL
VQLFLIFYGLPTLQIEIDPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTMGMTYTQALKRIILPQATRVSIPP
LSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAALMYWVICFLLSIVQQILEKRTERYILK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=205, Percent_Identity=50.7317073170732, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787030, Length=206, Percent_Identity=36.8932038834951, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=32.7102803738318, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786873, Length=211, Percent_Identity=34.1232227488152, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87082239, Length=182, Percent_Identity=37.9120879120879, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787087, Length=231, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788646, Length=218, Percent_Identity=28.8990825688073, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788645, Length=226, Percent_Identity=30.5309734513274, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=31.7647058823529, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=35.2459016393443, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26405; Mature: 26405

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLSNVFTLDRFSTWMDIMQASFMPMLKEAIFTTIPLTIITFIIGLILATLTALARISNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILQWIARIYVSIIRGTPLLVQLFLIFYGLPTLQIEIDPYTAAVIGFSLNVGAYASEIIR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHH
ASILSIPKGQWEAAYTMGMTYTQALKRIILPQATRVSIPPLSNTFISLVKDTSLASLILV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHH
TEMFRKAQEIAAMNYEFLIVYFEAALMYWVICFLLSIVQQILEKRTERYILK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLSNVFTLDRFSTWMDIMQASFMPMLKEAIFTTIPLTIITFIIGLILATLTALARISNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILQWIARIYVSIIRGTPLLVQLFLIFYGLPTLQIEIDPYTAAVIGFSLNVGAYASEIIR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHH
ASILSIPKGQWEAAYTMGMTYTQALKRIILPQATRVSIPPLSNTFISLVKDTSLASLILV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHH
TEMFRKAQEIAAMNYEFLIVYFEAALMYWVICFLLSIVQQILEKRTERYILK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]