Click here to switch to the map view.

The map label for this gene is tcyA [H]

Identifier: 152974511

GI number: 152974511

Start: 778574

End: 779371

Strand: Direct

Name: tcyA [H]

Synonym: Bcer98_0687

Alternate gene names: 152974511

Gene position: 778574-779371 (Clockwise)

Preceding gene: 152974510

Following gene: 152974512

Centisome position: 19.05

GC content: 37.47

Gene sequence:

>798_bases
ATGAAGAAATTATTTTCAGTGCTTGCGGTAGCTACTTTAGCAGTTGGGATTGTGGCAGGCTGTGGCAAAGAAGAGAAAAA
AGATACAGCTAGTCAAGATGCATTACAAAAAATTAAACAAAGCGGTGAACTTGTAATTGGTACAGAAGGTACATACCCAC
CATTTACATTCCATGATACGAGTAATAAATTAACTGGATTTGACGTTGAACTATCAGAAGAAGTTGCAAAGCGTTTAGGT
GTAAAGCCTGTCTTTAAAGAAACGCAATGGGATAGCTTGCTTGCAGGTTTAGATGCAAAACGCTTTGATATGGTGGCGAA
TGAAGTAGGAATTCGCGAGGACCGCCAAAAGAAATATGATTTCTCTAACCCATATGTTTCTTCTTCAGCGGCGTTAGTTA
TTGCGAAAGATAAAGATAAGCCAGCTACATTCACCGATGTGAAAGGGCTAAAAGCGGCGCAATCTTTAACAAGTAACTAC
GCGGACATCGCTAAGAAAAATGGCGCAGAAATCGTCGGTGTAGAAGGATTTAGCCAAGCTGCTGAATTATTAAATTCTGG
ACGCGTTGATTTCACAATTAATGATAAGTTATCCGTACTGAACTATTTAGAAACGAAAAAAGATGCGAACATTAAAATTG
TAGATACAGAAAAAGAAGCATCACAAAGTGGATTTTTATTCCGCAAAGGCAGCGGTAAATTAGTACAAGAAGTAAATAAA
GCGTTAGAAGATATGAAAAAAGATGGTACGTATGACAAAATAGCGAAAAAATGGTTCGGTGAAAATGTATCTAAGTAA

Upstream 100 bases:

>100_bases
TACACTAATGACGAACATTTTCATTGAAAAATTGTTCAAGATTGCATACAATCAATATAGTTTTTTAAAATTCCTATCAG
AATACTTGGAGGATTAGATC

Downstream 100 bases:

>100_bases
TGTATTCACCCTAGATCGTTTCTCTACGTGGATGGATATTATGCAAGCTTCCTTCATGCCTATGCTGAAGGAAGCCATTT
TTACGACAATTCCATTGACA

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKKLFSVLAVATLAVGIVAGCGKEEKKDTASQDALQKIKQSGELVIGTEGTYPPFTFHDTSNKLTGFDVELSEEVAKRLG
VKPVFKETQWDSLLAGLDAKRFDMVANEVGIREDRQKKYDFSNPYVSSSAALVIAKDKDKPATFTDVKGLKAAQSLTSNY
ADIAKKNGAEIVGVEGFSQAAELLNSGRVDFTINDKLSVLNYLETKKDANIKIVDTEKEASQSGFLFRKGSGKLVQEVNK
ALEDMKKDGTYDKIAKKWFGENVSK

Sequences:

>Translated_265_residues
MKKLFSVLAVATLAVGIVAGCGKEEKKDTASQDALQKIKQSGELVIGTEGTYPPFTFHDTSNKLTGFDVELSEEVAKRLG
VKPVFKETQWDSLLAGLDAKRFDMVANEVGIREDRQKKYDFSNPYVSSSAALVIAKDKDKPATFTDVKGLKAAQSLTSNY
ADIAKKNGAEIVGVEGFSQAAELLNSGRVDFTINDKLSVLNYLETKKDANIKIVDTEKEASQSGFLFRKGSGKLVQEVNK
ALEDMKKDGTYDKIAKKWFGENVSK
>Mature_265_residues
MKKLFSVLAVATLAVGIVAGCGKEEKKDTASQDALQKIKQSGELVIGTEGTYPPFTFHDTSNKLTGFDVELSEEVAKRLG
VKPVFKETQWDSLLAGLDAKRFDMVANEVGIREDRQKKYDFSNPYVSSSAALVIAKDKDKPATFTDVKGLKAAQSLTSNY
ADIAKKNGAEIVGVEGFSQAAELLNSGRVDFTINDKLSVLNYLETKKDANIKIVDTEKEASQSGFLFRKGSGKLVQEVNK
ALEDMKKDGTYDKIAKKWFGENVSK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=259, Percent_Identity=38.2239382239382, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787085, Length=221, Percent_Identity=29.8642533936652, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788648, Length=225, Percent_Identity=31.1111111111111, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787088, Length=223, Percent_Identity=32.7354260089686, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787031, Length=220, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788649, Length=228, Percent_Identity=30.2631578947368, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 28993; Mature: 28993

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFSVLAVATLAVGIVAGCGKEEKKDTASQDALQKIKQSGELVIGTEGTYPPFTFHDT
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEECC
SNKLTGFDVELSEEVAKRLGVKPVFKETQWDSLLAGLDAKRFDMVANEVGIREDRQKKYD
CCCCCCCCCCHHHHHHHHCCCCCHHHCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCC
FSNPYVSSSAALVIAKDKDKPATFTDVKGLKAAQSLTSNYADIAKKNGAEIVGVEGFSQA
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
AELLNSGRVDFTINDKLSVLNYLETKKDANIKIVDTEKEASQSGFLFRKGSGKLVQEVNK
HHHHHCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCHHHHHHHH
ALEDMKKDGTYDKIAKKWFGENVSK
HHHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKLFSVLAVATLAVGIVAGCGKEEKKDTASQDALQKIKQSGELVIGTEGTYPPFTFHDT
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEECC
SNKLTGFDVELSEEVAKRLGVKPVFKETQWDSLLAGLDAKRFDMVANEVGIREDRQKKYD
CCCCCCCCCCHHHHHHHHCCCCCHHHCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCC
FSNPYVSSSAALVIAKDKDKPATFTDVKGLKAAQSLTSNYADIAKKNGAEIVGVEGFSQA
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
AELLNSGRVDFTINDKLSVLNYLETKKDANIKIVDTEKEASQSGFLFRKGSGKLVQEVNK
HHHHHCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCHHHHHHHH
ALEDMKKDGTYDKIAKKWFGENVSK
HHHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]