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The map label for this gene is murQ

Identifier: 152974495

GI number: 152974495

Start: 756151

End: 757035

Strand: Direct

Name: murQ

Synonym: Bcer98_0670

Alternate gene names: 152974495

Gene position: 756151-757035 (Clockwise)

Preceding gene: 152974494

Following gene: 152974496

Centisome position: 18.5

GC content: 38.76

Gene sequence:

>885_bases
ATGTTAGAGCGTTTATCGACAGAATATCGGAATAAAAACACGATGAATTTAGATGAAATGAGTATAAAAGAGGTTTTAGA
GGCGATGAATCAAGAAGATCGTAAAGTCGCGATAGCAGTACACAAGGAGATGGAACAAATTGAAAAAATCGTTCGAAATG
TAATTTCATCTTTTCAAAATGGTGGACGCTTAATTTATATCGGTGCTGGGACAAGTGGCAGATTAGGTATTTTAGATGCT
GTTGAATGTCCTCCTACATTTGGTACAGATGAGAGACAAGTACAAGGATTTATAGCCGGAGGAATGAAAGCGTTTACTAA
GGCGGTGGAAGGTGCAGAGGATTGCGAGGAATTGGCGATAGAAGATTTAAAAGGGATTCAGCTAAATGATAAAGATACAG
TGATCGGAATTGCGGCGAGTGGTCGCACACCATATGTCATTGGTGGATTAAAATATGCAAATTATGTTGGGGCAAAGACA
GCGAGTATTTCTTGTAATAAAGGGGCTGAAATGAGTCAGTTAGCACAAGTGAGTGTAGAAGTAGAAACGGGTGCTGAAGT
GCTAACTGGATCGACACGATTAAAAGCGGGCACGGCTCAAAAGTTAGTACTCAATATGATTTCAACGGCTTCGATGATTG
GTATAGGAAAGGTATATAAAAACTTAATGGTCGATGTTCAATCAACCAATCAAAAATTAGTAGAACGTTCTAAACGAATT
ATTATGGAAGCAACAGAGGTAGATTACAAGGAGGCAGAGGCGTATTACGAAAAGGCAAATCGGAATGTGAAAGCAGCAAT
CGTTATGATATTACTACAGTGTGAATATGGGGAAGCACTTGAAAAATTAAAAGATGCAAAAGGATTTGTGAAGAAGGCGC
TATAG

Upstream 100 bases:

>100_bases
AATGAAAATGAAATTTCATAAAATGAATGGTGAATATTGATTTTAAATTTCTTAGTTATATAATAAAAGTGTGAAATAAA
ATTTCAAGGAGGGCGAAAGA

Downstream 100 bases:

>100_bases
AAATGGAGAGGAGAGATTCTACCATGAAGAAAGAACAGCGGATGGCAAATGACATTACAGAGCAACTTGGGGGAATACAA
AATGTACGCAGCATTGCACA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLERLSTEYRNKNTMNLDEMSIKEVLEAMNQEDRKVAIAVHKEMEQIEKIVRNVISSFQNGGRLIYIGAGTSGRLGILDA
VECPPTFGTDERQVQGFIAGGMKAFTKAVEGAEDCEELAIEDLKGIQLNDKDTVIGIAASGRTPYVIGGLKYANYVGAKT
ASISCNKGAEMSQLAQVSVEVETGAEVLTGSTRLKAGTAQKLVLNMISTASMIGIGKVYKNLMVDVQSTNQKLVERSKRI
IMEATEVDYKEAEAYYEKANRNVKAAIVMILLQCEYGEALEKLKDAKGFVKKAL

Sequences:

>Translated_294_residues
MLERLSTEYRNKNTMNLDEMSIKEVLEAMNQEDRKVAIAVHKEMEQIEKIVRNVISSFQNGGRLIYIGAGTSGRLGILDA
VECPPTFGTDERQVQGFIAGGMKAFTKAVEGAEDCEELAIEDLKGIQLNDKDTVIGIAASGRTPYVIGGLKYANYVGAKT
ASISCNKGAEMSQLAQVSVEVETGAEVLTGSTRLKAGTAQKLVLNMISTASMIGIGKVYKNLMVDVQSTNQKLVERSKRI
IMEATEVDYKEAEAYYEKANRNVKAAIVMILLQCEYGEALEKLKDAKGFVKKAL
>Mature_294_residues
MLERLSTEYRNKNTMNLDEMSIKEVLEAMNQEDRKVAIAVHKEMEQIEKIVRNVISSFQNGGRLIYIGAGTSGRLGILDA
VECPPTFGTDERQVQGFIAGGMKAFTKAVEGAEDCEELAIEDLKGIQLNDKDTVIGIAASGRTPYVIGGLKYANYVGAKT
ASISCNKGAEMSQLAQVSVEVETGAEVLTGSTRLKAGTAQKLVLNMISTASMIGIGKVYKNLMVDVQSTNQKLVERSKRI
IMEATEVDYKEAEAYYEKANRNVKAAIVMILLQCEYGEALEKLKDAKGFVKKAL

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=293, Percent_Identity=49.1467576791809, Blast_Score=274, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_BACCN (A7GLK9)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001374012.1
- ProteinModelPortal:   A7GLK9
- SMR:   A7GLK9
- STRING:   A7GLK9
- EnsemblBacteria:   EBBACT00000038927
- GeneID:   5346089
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_0670
- eggNOG:   COG2103
- GeneTree:   EBGT00050000002902
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- ProtClustDB:   PRK05441
- BioCyc:   BCER315749:BCER98_0670-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 32107; Mature: 32107

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 82-82 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERLSTEYRNKNTMNLDEMSIKEVLEAMNQEDRKVAIAVHKEMEQIEKIVRNVISSFQN
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
GGRLIYIGAGTSGRLGILDAVECPPTFGTDERQVQGFIAGGMKAFTKAVEGAEDCEELAI
CCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EDLKGIQLNDKDTVIGIAASGRTPYVIGGLKYANYVGAKTASISCNKGAEMSQLAQVSVE
HHHCCCEECCCCCEEEEEECCCCCEEEECCHHHHHCCCCCEEEECCCCCCHHHHHHHEEE
VETGAEVLTGSTRLKAGTAQKLVLNMISTASMIGIGKVYKNLMVDVQSTNQKLVERSKRI
ECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEATEVDYKEAEAYYEKANRNVKAAIVMILLQCEYGEALEKLKDAKGFVKKAL
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLERLSTEYRNKNTMNLDEMSIKEVLEAMNQEDRKVAIAVHKEMEQIEKIVRNVISSFQN
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
GGRLIYIGAGTSGRLGILDAVECPPTFGTDERQVQGFIAGGMKAFTKAVEGAEDCEELAI
CCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EDLKGIQLNDKDTVIGIAASGRTPYVIGGLKYANYVGAKTASISCNKGAEMSQLAQVSVE
HHHCCCEECCCCCEEEEEECCCCCEEEECCHHHHHCCCCCEEEECCCCCCHHHHHHHEEE
VETGAEVLTGSTRLKAGTAQKLVLNMISTASMIGIGKVYKNLMVDVQSTNQKLVERSKRI
ECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEATEVDYKEAEAYYEKANRNVKAAIVMILLQCEYGEALEKLKDAKGFVKKAL
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA