Click here to switch to the map view.

The map label for this gene is ygcA [C]

Identifier: 152974246

GI number: 152974246

Start: 468397

End: 469773

Strand: Direct

Name: ygcA [C]

Synonym: Bcer98_0412

Alternate gene names: 152974246

Gene position: 468397-469773 (Clockwise)

Preceding gene: 152974245

Following gene: 152974247

Centisome position: 11.46

GC content: 40.01

Gene sequence:

>1377_bases
GTGCAAAAGCAACATGAAAGCAAATTGCAAGTTGGCCAAACGTTTCCAGTGACCATTAAGCGTCTTGGGATTAACGGAGA
GGGCGTTGGTTATTTTAAGAGACAAGTTGTCTTTATTCCAGGAGCATTACCAGGTGAAGAAGTGGTTGCAGAGACAACGA
AAATTCAACGCGGTTTTGCGGAAGCAAAAGTGAAAAACATTCGTAAAGTTTCCCCACATCGCGTGAAAGCTCCGTGTCCA
GTATATGATAAATGCGGTGGTTGTCAGCTCCAGCATTTAGATTATGAGGAGCAATTAAATCAGAAGCGTGATATCGTTGT
ACAAGCATTTCAAAAGTATATGAAGAATAGTTTGGAAGAGAAGATTCGCCCGACGCTTGGTATGAAAGACCCATGGCACT
ATCGTAATAAAAGTCAATTACAAGTAGGAAGAAAAGACGAAAAAGTTATTACAGGATTATATGAGCAAAATTCACATCGT
CTAATTGATATTGCGCATTGTATGATTCAACATAAAGCAACAAACGAAGCGACGAAAGTCGTTAGACGTATTTTAGAGAA
GCTAAACATTTCTATTTATAATGAGCGGAAAGGGAAAGGGCTTATCCGTACAATTGTTACACGTGTAGCAGTCCAAACAG
GAGAAGTGCAAATTACGTTAATTACGGCAAAAGACGAATTTCCAAATAAAGAGCAGTTTATTGCAGAAGTACAAAAACAA
ATGCCAGCTGTGAAATCTATTATGCAAAATGTAAATGGACGTAAAACATCTGTTATTTTTGGGGATAAGACGTTCCACTT
AGCTGGGAAAGAAGTCATTCAAGAAACGCTCGGCGATTTATCATTTGAATTATCAGCGCGTGCCTTTTTCCAATTGAATC
CAGAGCAGACTGTTGTTCTTTACAATGAAGCGAAAAAAGCAGCAGCATTAACAGGAAAAGAAAAAATTGTAGATGCGTAT
TGTGGCGTTGGTACGATCGGACTGTGGCTTGCAAACGATGCAGCGGAAGTGCGCGGTATGGATGTCATTCCAGAAGCAAT
TGCAGATGCACGAAAAAATGCAAAACGCCACGGATTTACAAATACGAAATATGAAGCAGGGAAAGCTGAACAATGGTTAC
CGAAATGGGTAAAAGAAGGCTGGCACCCAGATGTAATCGTGGTGGATCCACCACGTACAGGTTGTGATGATAAATTGCTT
GAAACCATTTTAAAAGTACAACCAAAAACAGTTGTATACGTTTCTTGTAATCCATCTTCACTAGCACGCGATGTAAAAAC
ATTAATGAAGAGCTATGAAGTGGAATATGTACAGCCAGTGGACATGTTCCCGCATACAGCACACGTCGAGACAATAGTGT
TGCTACAACGACGCTAA

Upstream 100 bases:

>100_bases
GATGATGCACTTTTAGAACAAATAAAACAAGAGTGTGAACCATACTGTAGTTATGCAGCGTTATATTTATGGAAAAGTAT
AGAGTAGAGGTGTAATAATC

Downstream 100 bases:

>100_bases
GGCTAGAAATCCTTAATTTTAGGCAGTTTTACAAGCATATCGTCTTCACTGGTGAGGGGGATAAAATACGAAATAAGGAG
ATTCGAGACTACATCAATGT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQKQHESKLQVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKNIRKVSPHRVKAPCP
VYDKCGGCQLQHLDYEEQLNQKRDIVVQAFQKYMKNSLEEKIRPTLGMKDPWHYRNKSQLQVGRKDEKVITGLYEQNSHR
LIDIAHCMIQHKATNEATKVVRRILEKLNISIYNERKGKGLIRTIVTRVAVQTGEVQITLITAKDEFPNKEQFIAEVQKQ
MPAVKSIMQNVNGRKTSVIFGDKTFHLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYNEAKKAAALTGKEKIVDAY
CGVGTIGLWLANDAAEVRGMDVIPEAIADARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGWHPDVIVVDPPRTGCDDKLL
ETILKVQPKTVVYVSCNPSSLARDVKTLMKSYEVEYVQPVDMFPHTAHVETIVLLQRR

Sequences:

>Translated_458_residues
MQKQHESKLQVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKNIRKVSPHRVKAPCP
VYDKCGGCQLQHLDYEEQLNQKRDIVVQAFQKYMKNSLEEKIRPTLGMKDPWHYRNKSQLQVGRKDEKVITGLYEQNSHR
LIDIAHCMIQHKATNEATKVVRRILEKLNISIYNERKGKGLIRTIVTRVAVQTGEVQITLITAKDEFPNKEQFIAEVQKQ
MPAVKSIMQNVNGRKTSVIFGDKTFHLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYNEAKKAAALTGKEKIVDAY
CGVGTIGLWLANDAAEVRGMDVIPEAIADARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGWHPDVIVVDPPRTGCDDKLL
ETILKVQPKTVVYVSCNPSSLARDVKTLMKSYEVEYVQPVDMFPHTAHVETIVLLQRR
>Mature_458_residues
MQKQHESKLQVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKNIRKVSPHRVKAPCP
VYDKCGGCQLQHLDYEEQLNQKRDIVVQAFQKYMKNSLEEKIRPTLGMKDPWHYRNKSQLQVGRKDEKVITGLYEQNSHR
LIDIAHCMIQHKATNEATKVVRRILEKLNISIYNERKGKGLIRTIVTRVAVQTGEVQITLITAKDEFPNKEQFIAEVQKQ
MPAVKSIMQNVNGRKTSVIFGDKTFHLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYNEAKKAAALTGKEKIVDAY
CGVGTIGLWLANDAAEVRGMDVIPEAIADARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGWHPDVIVVDPPRTGCDDKLL
ETILKVQPKTVVYVSCNPSSLARDVKTLMKSYEVEYVQPVDMFPHTAHVETIVLLQRR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=215, Percent_Identity=35.3488372093023, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI51173878, Length=215, Percent_Identity=35.3488372093023, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI269784680, Length=206, Percent_Identity=33.0097087378641, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI269784676, Length=206, Percent_Identity=33.0097087378641, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI20149688, Length=206, Percent_Identity=33.0097087378641, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI269784678, Length=206, Percent_Identity=33.0097087378641, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789148, Length=452, Percent_Identity=27.212389380531, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787083, Length=380, Percent_Identity=25, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790403, Length=208, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322909, Length=443, Percent_Identity=25.0564334085779, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24666579, Length=417, Percent_Identity=28.537170263789, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51826; Mature: 51826

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50926 TRAM ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKQHESKLQVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFA
CCCCCCCHHHCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
EAKVKNIRKVSPHRVKAPCPVYDKCGGCQLQHLDYEEQLNQKRDIVVQAFQKYMKNSLEE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHH
KIRPTLGMKDPWHYRNKSQLQVGRKDEKVITGLYEQNSHRLIDIAHCMIQHKATNEATKV
HHCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHH
VRRILEKLNISIYNERKGKGLIRTIVTRVAVQTGEVQITLITAKDEFPNKEQFIAEVQKQ
HHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHH
MPAVKSIMQNVNGRKTSVIFGDKTFHLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVL
HHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHCCCEEEECCEEEEEECCCCEEEE
YNEAKKAAALTGKEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIADARKNAKRHGFT
EECCHHHHHHCCHHHHHHHHCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHCCCC
NTKYEAGKAEQWLPKWVKEGWHPDVIVVDPPRTGCDDKLLETILKVQPKTVVYVSCNPSS
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCHHH
LARDVKTLMKSYEVEYVQPVDMFPHTAHVETIVLLQRR
HHHHHHHHHHHCCCCEECCHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MQKQHESKLQVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFA
CCCCCCCHHHCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
EAKVKNIRKVSPHRVKAPCPVYDKCGGCQLQHLDYEEQLNQKRDIVVQAFQKYMKNSLEE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHH
KIRPTLGMKDPWHYRNKSQLQVGRKDEKVITGLYEQNSHRLIDIAHCMIQHKATNEATKV
HHCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHH
VRRILEKLNISIYNERKGKGLIRTIVTRVAVQTGEVQITLITAKDEFPNKEQFIAEVQKQ
HHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHH
MPAVKSIMQNVNGRKTSVIFGDKTFHLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVL
HHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHCCCEEEECCEEEEEECCCCEEEE
YNEAKKAAALTGKEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIADARKNAKRHGFT
EECCHHHHHHCCHHHHHHHHCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHCCCC
NTKYEAGKAEQWLPKWVKEGWHPDVIVVDPPRTGCDDKLLETILKVQPKTVVYVSCNPSS
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCHHH
LARDVKTLMKSYEVEYVQPVDMFPHTAHVETIVLLQRR
HHHHHHHHHHHCCCCEECCHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]