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The map label for this gene is yfjP [H]

Identifier: 152974245

GI number: 152974245

Start: 467520

End: 468383

Strand: Direct

Name: yfjP [H]

Synonym: Bcer98_0411

Alternate gene names: 152974245

Gene position: 467520-468383 (Clockwise)

Preceding gene: 152974244

Following gene: 152974246

Centisome position: 11.44

GC content: 35.42

Gene sequence:

>864_bases
ATGTGGAGTGAACATGTTACGTTAAAGAGTCCGTACCATTTTGAAGAAGTATTAAGGCGCTTATCTTTTGATCCATTACA
TCGTGTTCAATTAGATGAGAAAATCGTGTATGTTCCACTGTTTATAAATGGAGAACAAATTGTTGTTCGCATACAAGGGC
TAGGAACAATCGAGAAACCACAATTTTGGATTTCGAGCGAGACAGGTCAGCGCGAACAAGTTATGGAACGGATTTATACT
ATTTTCCAGTGGAATGAATCTTTGCAAAAGATACAAGACCATTTTCAAAACACATCACTACATCCACTTTTTGAAACATA
TGCGTATACACCGCTTATTTTAGAATTTGATTATTTTGCTTGTCTGCTTCGATGTATCATTCACCAACAAGTTAATTTAA
AGTTTGCTACTGTTCTTACGGAACAATTTGTAAAGACATATGGAACAGAGAAGAATGACGTTTTCTTTTTTCCAACGCCA
GAAAGAGTAGCAAAGATTTCAATAGAAGAACTTAGAGGACAAAAGTTTAGTCAACGAAAAGCGGAGTATATGATCGGATT
AGCAAAACAGATTGTGGAAGGTAAGCTTAATTTGTCAAAGTTAGAAAAACAAACAGAGGAAGAAATTTCTGCACAATTGT
TACCAGTACGAGGCATTGGAGCATGGACAGTGCAAAATTTTTTATTATTTGGACTTGGGCGCCGAAATATGTTTCCCAAA
ACAGATATCGGAATTCAGCGTGCACTACAAAGATTATTTCAATTAGACAATAAGCCAGATGATGCACTTTTAGAACAAAT
AAAACAAGAGTGTGAACCATACTGTAGTTATGCAGCGTTATATTTATGGAAAAGTATAGAGTAG

Upstream 100 bases:

>100_bases
TTAAAAGTCTAGATGATTTAGTAAAACGCAATCAACCGTAAGCATGTATGCTTGCGGTTTTCTCATGCTATAATGATGTG
TAAAAAGGATGGGGAAACGT

Downstream 100 bases:

>100_bases
AGGTGTAATAATCGTGCAAAAGCAACATGAAAGCAAATTGCAAGTTGGCCAAACGTTTCCAGTGACCATTAAGCGTCTTG
GGATTAACGGAGAGGGCGTT

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MWSEHVTLKSPYHFEEVLRRLSFDPLHRVQLDEKIVYVPLFINGEQIVVRIQGLGTIEKPQFWISSETGQREQVMERIYT
IFQWNESLQKIQDHFQNTSLHPLFETYAYTPLILEFDYFACLLRCIIHQQVNLKFATVLTEQFVKTYGTEKNDVFFFPTP
ERVAKISIEELRGQKFSQRKAEYMIGLAKQIVEGKLNLSKLEKQTEEEISAQLLPVRGIGAWTVQNFLLFGLGRRNMFPK
TDIGIQRALQRLFQLDNKPDDALLEQIKQECEPYCSYAALYLWKSIE

Sequences:

>Translated_287_residues
MWSEHVTLKSPYHFEEVLRRLSFDPLHRVQLDEKIVYVPLFINGEQIVVRIQGLGTIEKPQFWISSETGQREQVMERIYT
IFQWNESLQKIQDHFQNTSLHPLFETYAYTPLILEFDYFACLLRCIIHQQVNLKFATVLTEQFVKTYGTEKNDVFFFPTP
ERVAKISIEELRGQKFSQRKAEYMIGLAKQIVEGKLNLSKLEKQTEEEISAQLLPVRGIGAWTVQNFLLFGLGRRNMFPK
TDIGIQRALQRLFQLDNKPDDALLEQIKQECEPYCSYAALYLWKSIE
>Mature_287_residues
MWSEHVTLKSPYHFEEVLRRLSFDPLHRVQLDEKIVYVPLFINGEQIVVRIQGLGTIEKPQFWISSETGQREQVMERIYT
IFQWNESLQKIQDHFQNTSLHPLFETYAYTPLILEFDYFACLLRCIIHQQVNLKFATVLTEQFVKTYGTEKNDVFFFPTP
ERVAKISIEELRGQKFSQRKAEYMIGLAKQIVEGKLNLSKLEKQTEEEISAQLLPVRGIGAWTVQNFLLFGLGRRNMFPK
TDIGIQRALQRLFQLDNKPDDALLEQIKQECEPYCSYAALYLWKSIE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=170, Percent_Identity=28.8235294117647, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320990, Length=232, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 33793; Mature: 33793

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSEHVTLKSPYHFEEVLRRLSFDPLHRVQLDEKIVYVPLFINGEQIVVRIQGLGTIEKP
CCCCCEEECCCCCHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCEEEEEEECCCCCCCC
QFWISSETGQREQVMERIYTIFQWNESLQKIQDHFQNTSLHPLFETYAYTPLILEFDYFA
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHEEEHHHHH
CLLRCIIHQQVNLKFATVLTEQFVKTYGTEKNDVFFFPTPERVAKISIEELRGQKFSQRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHH
AEYMIGLAKQIVEGKLNLSKLEKQTEEEISAQLLPVRGIGAWTVQNFLLFGLGRRNMFPK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCC
TDIGIQRALQRLFQLDNKPDDALLEQIKQECEPYCSYAALYLWKSIE
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWSEHVTLKSPYHFEEVLRRLSFDPLHRVQLDEKIVYVPLFINGEQIVVRIQGLGTIEKP
CCCCCEEECCCCCHHHHHHHCCCCCHHHHCCCCEEEEEEEEECCCEEEEEEECCCCCCCC
QFWISSETGQREQVMERIYTIFQWNESLQKIQDHFQNTSLHPLFETYAYTPLILEFDYFA
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHEEEHHHHH
CLLRCIIHQQVNLKFATVLTEQFVKTYGTEKNDVFFFPTPERVAKISIEELRGQKFSQRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHH
AEYMIGLAKQIVEGKLNLSKLEKQTEEEISAQLLPVRGIGAWTVQNFLLFGLGRRNMFPK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCC
TDIGIQRALQRLFQLDNKPDDALLEQIKQECEPYCSYAALYLWKSIE
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]