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The map label for this gene is ygcA [C]

Identifier: 152974152

GI number: 152974152

Start: 357767

End: 359143

Strand: Direct

Name: ygcA [C]

Synonym: Bcer98_0311

Alternate gene names: 152974152

Gene position: 357767-359143 (Clockwise)

Preceding gene: 152974148

Following gene: 152974153

Centisome position: 8.75

GC content: 41.76

Gene sequence:

>1377_bases
ATGAGTAATAAAATGACGCCACCAGTTGAAAAAAACGAGTTTATAGATGTAGTATTTGAAGATTTAACCCATGATGGTGC
CGGTGTTGCGAAAGTGGACGGATATCCCATTTTCGTCAAAAACGGATTACCAGGTGAAAAAGCGCAAATTAAAATTATTA
AAGTAAAAAAGAATTTCGCATTTGGCCGCTTAATGAAGCTTTACACAGAAAGTCCATATCGTAAAGAGGCAGAGTGCCCG
GTTTACAACCAATGCGGTGGTTGCCAGCTTCAGCACGTAACGTATGAAGGACAGTTAGCAGCGAAGCAAAAGCAAGTACG
TGATGTCATGCAGCGTATTGGAGGTCTTCATGACGTGCCAGTTCACCCTGTTCTCGGTATGGAAAATCCGTGGGTGTATC
GCAACAAAGCACAAGTGCCAATTGGAGAACGTGAAGGCGGACTAGTAGCGGGTTTTTACCGTCAAGGGACGCATGATATT
ATCAATATGGAAACGTGCTTAATTCAAGCGGAAGAGAACGATACATTAATTCAAGAAGTGAAACGCATTTGTGAAACGCA
TGGCATTCGTGCGTACAATGAAGAACGTCATAAAGGCACACTTCGCCACGTAATGGCAAGATATGGACACGTAACAGGGG
AAATTATGCTTGTTTTCATCACGCGCACGGCAGAACTTCCAAATAAAAAGGCGATAATCGAAGAAATTACAGCGAAATTC
CCAAATGTAAAATCAATTGTTCAAAACGTAAACACGAAACGTACAAATGTTATTTTTGGAGAGACAACAACAGTTCTATA
TGGATCAGAATATATTTATGACTTTATCGGTGATATTCAATTTGCGATTTCAGCGCGTTCGTTCTATCAAGTAAACCCAG
AGCAAACGAAAGTGCTATACGATAAAGCATTAGAATATGCACAACTAGACGGAAATGAAACAGTTATTGATGCGTACTGC
GGAATCGGATCCATTTCTCTATTCTTAGCGCAAAAAGCGAAAAAAGTATATGGCGTTGAAATTGTGCCAGAAGCAATCGA
AGACGCAAAGCGAAACGCAGAACTCAACAACATGACAAATGCAGAATTTGCAGTTGGAGAAGCGGAAGTTGTCATTCCAA
ACTGGTACAAAGAAGGCGTAATCGCCGACACAATCGTCGTCGACCCTCCGCGCAAAGGTTGCGATGAAGCATTACTAAAT
ACAATCATCGACATGAAACCAAAGCGCGTCGTATACGTATCATGTAACCCAGCAACACTTGCACGCGACTTAAAAGTACT
AGAAGAAGGCGGGTATAAAACACAAGAAGTACAGCCTGTTGATATGTTCCCGCATACGACTCACGTGGAGTGTGTAGCTT
GGCTTAAGTTGGTATAA

Upstream 100 bases:

>100_bases
ATAGAGAAGTGTCGTCAATAGCTTTTTTTCTTCCAATAGAAAAAGACTATGTAAGTATGATAAAATGTAACGCAGTGTTA
TGAAAAAGAGAGGTCGGAAA

Downstream 100 bases:

>100_bases
TAAAAAAGCAGTTGATATAGAAAAAATCTATACCATCTGCTTTTTGGTTTATAAATATTGCTGATTTTTAAAAATAATAA
ATGTTCAAATGTACTGGTGT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSNKMTPPVEKNEFIDVVFEDLTHDGAGVAKVDGYPIFVKNGLPGEKAQIKIIKVKKNFAFGRLMKLYTESPYRKEAECP
VYNQCGGCQLQHVTYEGQLAAKQKQVRDVMQRIGGLHDVPVHPVLGMENPWVYRNKAQVPIGEREGGLVAGFYRQGTHDI
INMETCLIQAEENDTLIQEVKRICETHGIRAYNEERHKGTLRHVMARYGHVTGEIMLVFITRTAELPNKKAIIEEITAKF
PNVKSIVQNVNTKRTNVIFGETTTVLYGSEYIYDFIGDIQFAISARSFYQVNPEQTKVLYDKALEYAQLDGNETVIDAYC
GIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAELNNMTNAEFAVGEAEVVIPNWYKEGVIADTIVVDPPRKGCDEALLN
TIIDMKPKRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV

Sequences:

>Translated_458_residues
MSNKMTPPVEKNEFIDVVFEDLTHDGAGVAKVDGYPIFVKNGLPGEKAQIKIIKVKKNFAFGRLMKLYTESPYRKEAECP
VYNQCGGCQLQHVTYEGQLAAKQKQVRDVMQRIGGLHDVPVHPVLGMENPWVYRNKAQVPIGEREGGLVAGFYRQGTHDI
INMETCLIQAEENDTLIQEVKRICETHGIRAYNEERHKGTLRHVMARYGHVTGEIMLVFITRTAELPNKKAIIEEITAKF
PNVKSIVQNVNTKRTNVIFGETTTVLYGSEYIYDFIGDIQFAISARSFYQVNPEQTKVLYDKALEYAQLDGNETVIDAYC
GIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAELNNMTNAEFAVGEAEVVIPNWYKEGVIADTIVVDPPRKGCDEALLN
TIIDMKPKRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
>Mature_457_residues
SNKMTPPVEKNEFIDVVFEDLTHDGAGVAKVDGYPIFVKNGLPGEKAQIKIIKVKKNFAFGRLMKLYTESPYRKEAECPV
YNQCGGCQLQHVTYEGQLAAKQKQVRDVMQRIGGLHDVPVHPVLGMENPWVYRNKAQVPIGEREGGLVAGFYRQGTHDII
NMETCLIQAEENDTLIQEVKRICETHGIRAYNEERHKGTLRHVMARYGHVTGEIMLVFITRTAELPNKKAIIEEITAKFP
NVKSIVQNVNTKRTNVIFGETTTVLYGSEYIYDFIGDIQFAISARSFYQVNPEQTKVLYDKALEYAQLDGNETVIDAYCG
IGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAELNNMTNAEFAVGEAEVVIPNWYKEGVIADTIVVDPPRKGCDEALLNT
IIDMKPKRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=344, Percent_Identity=28.4883720930233, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI51173878, Length=344, Percent_Identity=28.4883720930233, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI269784678, Length=256, Percent_Identity=29.6875, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI269784680, Length=256, Percent_Identity=29.6875, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI269784676, Length=256, Percent_Identity=29.6875, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI20149688, Length=256, Percent_Identity=29.6875, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1789148, Length=450, Percent_Identity=31.3333333333333, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787083, Length=387, Percent_Identity=27.390180878553, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790403, Length=177, Percent_Identity=29.9435028248588, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71997438, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322909, Length=442, Percent_Identity=24.6606334841629, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24666579, Length=411, Percent_Identity=30.6569343065693, Blast_Score=158, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280
- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10; PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51478; Mature: 51347

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKMTPPVEKNEFIDVVFEDLTHDGAGVAKVDGYPIFVKNGLPGEKAQIKIIKVKKNFA
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCEEEEEEEECCCH
FGRLMKLYTESPYRKEAECPVYNQCGGCQLQHVTYEGQLAAKQKQVRDVMQRIGGLHDVP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
VHPVLGMENPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINMETCLIQAEENDTLIQEV
CCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCHHHHHH
KRICETHGIRAYNEERHKGTLRHVMARYGHVTGEIMLVFITRTAELPNKKAIIEEITAKF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCC
PNVKSIVQNVNTKRTNVIFGETTTVLYGSEYIYDFIGDIQFAISARSFYQVNPEQTKVLY
CCHHHHHHCCCCCCCEEEECCCEEEEECCHHHHHHHCCCEEEEEECEEEEECHHHHHHHH
DKALEYAQLDGNETVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAELNNMTN
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECHHHHHHHHHCCCCCCCCC
AEFAVGEAEVVIPNWYKEGVIADTIVVDPPRKGCDEALLNTIIDMKPKRVVYVSCNPATL
CEEEECCEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHH
ARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SNKMTPPVEKNEFIDVVFEDLTHDGAGVAKVDGYPIFVKNGLPGEKAQIKIIKVKKNFA
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCEEEEEEEECCCH
FGRLMKLYTESPYRKEAECPVYNQCGGCQLQHVTYEGQLAAKQKQVRDVMQRIGGLHDVP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
VHPVLGMENPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINMETCLIQAEENDTLIQEV
CCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCHHHHHH
KRICETHGIRAYNEERHKGTLRHVMARYGHVTGEIMLVFITRTAELPNKKAIIEEITAKF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCC
PNVKSIVQNVNTKRTNVIFGETTTVLYGSEYIYDFIGDIQFAISARSFYQVNPEQTKVLY
CCHHHHHHCCCCCCCEEEECCCEEEEECCHHHHHHHCCCEEEEEECEEEEECHHHHHHHH
DKALEYAQLDGNETVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAELNNMTN
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECHHHHHHHHHCCCCCCCCC
AEFAVGEAEVVIPNWYKEGVIADTIVVDPPRKGCDEALLNTIIDMKPKRVVYVSCNPATL
CEEEECCEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHH
ARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA