Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 152974143

GI number: 152974143

Start: 346240

End: 346986

Strand: Direct

Name: gph [C]

Synonym: Bcer98_0302

Alternate gene names: 152974143

Gene position: 346240-346986 (Clockwise)

Preceding gene: 152974141

Following gene: 152974144

Centisome position: 8.47

GC content: 35.21

Gene sequence:

>747_bases
ATGGAGAAGATCAAAGCAATATTATTTGATAAAGATGGTACATTAATGGATTTTCATTCCGTTTGGGTAAAAGTGGCCGA
AGAACTTGTCGCTGAGCTTATAAAGGTATATGATTTACCACAATCTTTACAACAAACGCTTTTAAGTGAAATAGGTGTAG
AAGAAAATTTTGTTCATCCTGAGAGTGCCTTAGCAGCTGGAACAAGTCGTGATGTAGCAAAAGTATTTTGTGAATATATT
TCATCAGAAAAAGAAGAGAATATGTCTCAGTGGGTGAGTCAGCAATTATTTACTCTTATGTATGAACACCGCTCTCATAT
GAAAATGACCGCGAATATTCCGGAAATTTTGCAAGCGTTGAAAGATAGAGAATTTATTTTAGGTGTTGTAACAGCTGATG
ATTTAGCGCCAACAGAATTATTCTTGAAGCAATATCAATTGGAATCTTTCTTTGATTGTATAATTACTTCTGACACTTTC
CCAGCACAAAAACCAGATAAAAAAATTATAGAATTCATTTGCGAAAGATTTCATCTCATACCGTCAGAAATTGCTGTTAT
TGGAGATACCCCAACAGATTTACATTTAGCGAAAAATAGCGGGGATTGTTATGCGATTGGTGTGCTATCTGGGACTGGGG
ATTATCAAACTTTAGCACCGCTTGCCGATCTTATATTAGATTCGGTAGGAGATCTAATTTCAAGTTCTGGTACACTTCTT
TTTGAACAAGTAAAGCCTAATAGGTAA

Upstream 100 bases:

>100_bases
GAAGTTTGTTTGTTTTTTATGGCATCTTTACAATATATTCATTTTTTATCCATATTTCCTTGTTACAATGGGAGAGAGAA
GAAGAGAAAGGTGGGGGGTT

Downstream 100 bases:

>100_bases
ATAAAATAAGTCTATACTGACTTGAAATAAGTCGTTATAGACTTATTTTTTATGTTGAAATATAAAGAAAAAGGGAAGAA
TGCTAGGATCATAAGTTGGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEKIKAILFDKDGTLMDFHSVWVKVAEELVAELIKVYDLPQSLQQTLLSEIGVEENFVHPESALAAGTSRDVAKVFCEYI
SSEKEENMSQWVSQQLFTLMYEHRSHMKMTANIPEILQALKDREFILGVVTADDLAPTELFLKQYQLESFFDCIITSDTF
PAQKPDKKIIEFICERFHLIPSEIAVIGDTPTDLHLAKNSGDCYAIGVLSGTGDYQTLAPLADLILDSVGDLISSSGTLL
FEQVKPNR

Sequences:

>Translated_248_residues
MEKIKAILFDKDGTLMDFHSVWVKVAEELVAELIKVYDLPQSLQQTLLSEIGVEENFVHPESALAAGTSRDVAKVFCEYI
SSEKEENMSQWVSQQLFTLMYEHRSHMKMTANIPEILQALKDREFILGVVTADDLAPTELFLKQYQLESFFDCIITSDTF
PAQKPDKKIIEFICERFHLIPSEIAVIGDTPTDLHLAKNSGDCYAIGVLSGTGDYQTLAPLADLILDSVGDLISSSGTLL
FEQVKPNR
>Mature_248_residues
MEKIKAILFDKDGTLMDFHSVWVKVAEELVAELIKVYDLPQSLQQTLLSEIGVEENFVHPESALAAGTSRDVAKVFCEYI
SSEKEENMSQWVSQQLFTLMYEHRSHMKMTANIPEILQALKDREFILGVVTADDLAPTELFLKQYQLESFFDCIITSDTF
PAQKPDKKIIEFICERFHLIPSEIAVIGDTPTDLHLAKNSGDCYAIGVLSGTGDYQTLAPLADLILDSVGDLISSSGTLL
FEQVKPNR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 27795; Mature: 27795

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIKAILFDKDGTLMDFHSVWVKVAEELVAELIKVYDLPQSLQQTLLSEIGVEENFVHP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
ESALAAGTSRDVAKVFCEYISSEKEENMSQWVSQQLFTLMYEHRSHMKMTANIPEILQAL
HHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHH
KDREFILGVVTADDLAPTELFLKQYQLESFFDCIITSDTFPAQKPDKKIIEFICERFHLI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
PSEIAVIGDTPTDLHLAKNSGDCYAIGVLSGTGDYQTLAPLADLILDSVGDLISSSGTLL
CHHEEEECCCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
FEQVKPNR
EECCCCCC
>Mature Secondary Structure
MEKIKAILFDKDGTLMDFHSVWVKVAEELVAELIKVYDLPQSLQQTLLSEIGVEENFVHP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
ESALAAGTSRDVAKVFCEYISSEKEENMSQWVSQQLFTLMYEHRSHMKMTANIPEILQAL
HHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHH
KDREFILGVVTADDLAPTELFLKQYQLESFFDCIITSDTFPAQKPDKKIIEFICERFHLI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
PSEIAVIGDTPTDLHLAKNSGDCYAIGVLSGTGDYQTLAPLADLILDSVGDLISSSGTLL
CHHEEEECCCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
FEQVKPNR
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA