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The map label for this gene is pabB [H]

Identifier: 152973917

GI number: 152973917

Start: 74965

End: 76362

Strand: Direct

Name: pabB [H]

Synonym: Bcer98_0064

Alternate gene names: 152973917

Gene position: 74965-76362 (Clockwise)

Preceding gene: 152973916

Following gene: 152973918

Centisome position: 1.83

GC content: 37.91

Gene sequence:

>1398_bases
ATGCAGCAAAGGAAATCTTTGGCGCTCTCTATTCCATATCATTTTGATTTCTTTAAGCAATATAAGTTTCTCTCTCAGTA
CAAGACGCAACATATTTTGTTAGAAAGTGGGCGCGGAGGTCGCTATAGTATTGTAGGACTCGATCCTGTAGCGGTCATTC
GTGGGAAGAATGAAACGTTGCATATAAGTGAAAATGGTAAGGAAACAATAGAATATGGGAATCCATTAAATTTAATGCAA
AAATATATGGAGCAATGGAAAACAGATCACAATCCAGATTATCCGCCATTTCAAGGGGGGGCAATCGGATATTTTAGTTA
TGATTGTATTCGTTACATTGAGAAATTGCCTTCAATTGCAAAGGATGATGTGGATATACCTGACATATTCTTTCTATTAT
TTGATGATGTGTTTGTATACGATCATCATGAAAAGGTATTATGGATTATTACGCATTATGTAGAGGAACGTGAAAATGCA
GAACAACGCTTGAGAGATTGGGAAGAACTTTGGATGAAGGAAGCCCCTCAAGTGAAAATTCCATTTGAAAGCCAGGCAAA
CGAAAAAGAAGTTGTAGCTTTCACAGAAGAAGGATTTATACATGCGGTTGAGCGTATTCAAGAGTATATTGGAGCAGGAG
ATGTGTTTCAAGTGAACCTTTCTACAAGACAAGAAAAAACACTGCAAACACACCCTTTTGAAATTTATACAAGCTTAAGG
GAAATCAATCCATCCCCATACATGGGGTACTTAGAACTTGGGGATTTTCAAATTGTGAGCGGCTCACCGGAATTATTAAT
TAAAAAACAAGGAAATAAGGTGAGTACAAGACCGATTGCAGGAACACGTTCTCGCGGGGATAATGAACAAGAAGATGAAA
GATTAGCGAAGGAGCTCATTGAAAATGAAAAAGAACGTGCAGAACATGTAATGCTTGTTGACTTAGAACGGAATGATTTA
GGAAGAGTTTGTGAGTATGGGACAGTTGAAGTGGATGAATTTATGGTAATTGAAAAATACTCGCATGTTATGCATATTGT
TTCGAATGTTCGCGGTTTAGTGAGTGAAGATAAGGATGCTTTTGATTTAGTAAGAGCTGTATTTCCTGGTGGTACCATTA
CGGGAGCGCCTAAAATACGTACAATGGAAATTATAGAAGAGTTAGAACCTGTAAGACGCGGTATTTATACAGGATCAATA
GGTTGGATAGGGTACTCTGGAGATATGGAATTAAATATTGTGATTCGAACGTTGCTTGCAAAAGATGGTCAAGCATATGT
ACAAGCTGGAGCGGGAATTGTCATTGATTCAAGTCCGAAGAATGAGTATAAAGAATCGTTGAAAAAAGCAATCGCTTTAT
GGCGTGCGAAAGAACGTAGTGAAGAAACGGTTAGGTGA

Upstream 100 bases:

>100_bases
TATTTTCATTAGCTCTCATGGATGAGTGTTTCATATCAGTTATTGGTGATTTGAGATAATCAGACTAGGGGAGTGGGATA
AAAGAAGATGGGGTGTTGAT

Downstream 100 bases:

>100_bases
GAGAAATGATATTAATGATCGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAGCTTGGACAAAAA
CTTGTCGTAAAGCGTAATGA

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQQRKSLALSIPYHFDFFKQYKFLSQYKTQHILLESGRGGRYSIVGLDPVAVIRGKNETLHISENGKETIEYGNPLNLMQ
KYMEQWKTDHNPDYPPFQGGAIGYFSYDCIRYIEKLPSIAKDDVDIPDIFFLLFDDVFVYDHHEKVLWIITHYVEERENA
EQRLRDWEELWMKEAPQVKIPFESQANEKEVVAFTEEGFIHAVERIQEYIGAGDVFQVNLSTRQEKTLQTHPFEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGNKVSTRPIAGTRSRGDNEQEDERLAKELIENEKERAEHVMLVDLERNDL
GRVCEYGTVEVDEFMVIEKYSHVMHIVSNVRGLVSEDKDAFDLVRAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDMELNIVIRTLLAKDGQAYVQAGAGIVIDSSPKNEYKESLKKAIALWRAKERSEETVR

Sequences:

>Translated_465_residues
MQQRKSLALSIPYHFDFFKQYKFLSQYKTQHILLESGRGGRYSIVGLDPVAVIRGKNETLHISENGKETIEYGNPLNLMQ
KYMEQWKTDHNPDYPPFQGGAIGYFSYDCIRYIEKLPSIAKDDVDIPDIFFLLFDDVFVYDHHEKVLWIITHYVEERENA
EQRLRDWEELWMKEAPQVKIPFESQANEKEVVAFTEEGFIHAVERIQEYIGAGDVFQVNLSTRQEKTLQTHPFEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGNKVSTRPIAGTRSRGDNEQEDERLAKELIENEKERAEHVMLVDLERNDL
GRVCEYGTVEVDEFMVIEKYSHVMHIVSNVRGLVSEDKDAFDLVRAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDMELNIVIRTLLAKDGQAYVQAGAGIVIDSSPKNEYKESLKKAIALWRAKERSEETVR
>Mature_465_residues
MQQRKSLALSIPYHFDFFKQYKFLSQYKTQHILLESGRGGRYSIVGLDPVAVIRGKNETLHISENGKETIEYGNPLNLMQ
KYMEQWKTDHNPDYPPFQGGAIGYFSYDCIRYIEKLPSIAKDDVDIPDIFFLLFDDVFVYDHHEKVLWIITHYVEERENA
EQRLRDWEELWMKEAPQVKIPFESQANEKEVVAFTEEGFIHAVERIQEYIGAGDVFQVNLSTRQEKTLQTHPFEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGNKVSTRPIAGTRSRGDNEQEDERLAKELIENEKERAEHVMLVDLERNDL
GRVCEYGTVEVDEFMVIEKYSHVMHIVSNVRGLVSEDKDAFDLVRAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDMELNIVIRTLLAKDGQAYVQAGAGIVIDSSPKNEYKESLKKAIALWRAKERSEETVR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=426, Percent_Identity=38.0281690140845, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1787518, Length=366, Percent_Identity=37.1584699453552, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1786809, Length=206, Percent_Identity=29.6116504854369, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082077, Length=218, Percent_Identity=22.9357798165138, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=476, Percent_Identity=39.2857142857143, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6324361, Length=411, Percent_Identity=25.7907542579075, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 53578; Mature: 53578

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRKSLALSIPYHFDFFKQYKFLSQYKTQHILLESGRGGRYSIVGLDPVAVIRGKNETL
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCEEEEECCCCEE
HISENGKETIEYGNPLNLMQKYMEQWKTDHNPDYPPFQGGAIGYFSYDCIRYIEKLPSIA
EECCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCHH
KDDVDIPDIFFLLFDDVFVYDHHEKVLWIITHYVEERENAEQRLRDWEELWMKEAPQVKI
CCCCCCHHHHHHHHHHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
PFESQANEKEVVAFTEEGFIHAVERIQEYIGAGDVFQVNLSTRQEKTLQTHPFEIYTSLR
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCHHHHHHHH
EINPSPYMGYLELGDFQIVSGSPELLIKKQGNKVSTRPIAGTRSRGDNEQEDERLAKELI
HCCCCCCEEEEEECCEEEECCCCCEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHH
ENEKERAEHVMLVDLERNDLGRVCEYGTVEVDEFMVIEKYSHVMHIVSNVRGLVSEDKDA
HCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FDLVRAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDMELNIVIRTLLA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCEEEHHHHHHHHH
KDGQAYVQAGAGIVIDSSPKNEYKESLKKAIALWRAKERSEETVR
CCCHHEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQQRKSLALSIPYHFDFFKQYKFLSQYKTQHILLESGRGGRYSIVGLDPVAVIRGKNETL
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCEEEEECCCCEE
HISENGKETIEYGNPLNLMQKYMEQWKTDHNPDYPPFQGGAIGYFSYDCIRYIEKLPSIA
EECCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCHH
KDDVDIPDIFFLLFDDVFVYDHHEKVLWIITHYVEERENAEQRLRDWEELWMKEAPQVKI
CCCCCCHHHHHHHHHHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
PFESQANEKEVVAFTEEGFIHAVERIQEYIGAGDVFQVNLSTRQEKTLQTHPFEIYTSLR
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCHHHHHHHH
EINPSPYMGYLELGDFQIVSGSPELLIKKQGNKVSTRPIAGTRSRGDNEQEDERLAKELI
HCCCCCCEEEEEECCEEEECCCCCEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHH
ENEKERAEHVMLVDLERNDLGRVCEYGTVEVDEFMVIEKYSHVMHIVSNVRGLVSEDKDA
HCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FDLVRAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDMELNIVIRTLLA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCEEEHHHHHHHHH
KDGQAYVQAGAGIVIDSSPKNEYKESLKKAIALWRAKERSEETVR
CCCHHEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]