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The map label for this gene is sbcB [H]

Identifier: 152971008

GI number: 152971008

Start: 2691482

End: 2692906

Strand: Direct

Name: sbcB [H]

Synonym: KPN_02469

Alternate gene names: 152971008

Gene position: 2691482-2692906 (Clockwise)

Preceding gene: 152971001

Following gene: 152971010

Centisome position: 50.64

GC content: 60.14

Gene sequence:

>1425_bases
ATGCAAGATAGCGTCAACCAGCCCGGATTTTTATTCCACGATTATGAAACCTTCGGCACCAGCCCTTCCCTCGACCGGCC
GGCGCAGTTCGCCGCCATCCGCACCGACGCGGAGCTGAATGTGCTCGGCGAGCCCGAAGTGTTTTACTGCAAACCCGCTG
ACGATTACCTGCCGCAGCCGCAGGCGGTGATGATCACCGGGATCACGCCGCAGGAAGCGCTGGCCAAAGGGGATAATGAG
GCCACATTTGCCCGCCGCATCCACGATCTGTTCACGGTGCCGCAAACCTGTATCGTCGGCTATAACAACGTGCGCTTTGA
TGACGAAGTGACGCGGAATATCTTCTATCGCAACTTCTATGACCCTTATGCCTGGAGCTGGCAGCACGATAACTCGCGCT
GGGATCTGCTCGACGTGATGCGCGCCTGCTATGCCCTGCGCCCTGAAGGGATCGCCTGGCCGGAGAATGACGAAGGGTTG
CCGAGCTTCCGGCTTGAACATCTGACCGTCGCCAACGGTATTGAACACCAGAACGCCCATGACGCGATGGCCGACGTATA
CGCCACCATCGCCATGGCGAAGCTGGTGAAAACCCGGCAGCCGCGGCTGTTTGATTATCTCTACAGCCACCGCAATAAGC
GCAAGCTGGCGACGCTTATCGACGTGCCGCAGATGAAGCCCCTGGTGCATGTCTCCGGCATGTTTGGCGCCGCGCGCGGC
AACACCAGCCTGGTGGCGCCCCTGGCCTGGCATCCGGAAAACCGCAATGCGGTGATTATGGTCGATCTGGCGGGCGATAT
GGCGCCACTGCTGGAACTGGATGCCGATGCCCTGCGCGAGCGGCTTTACACCCCGCGCGCCGAGCTTGGCGATCTGCCGG
CGGCGCCGATCAAGCTGGTGCATTTAAATAAATGTCCGGTACTGGCCCAGGCCAATACCCTGCGCCCGCAGGATGCCGAC
CGGCTGGGGATCTCCATTCAGCGCTGTCTGGAGAACGCCCAGCTGCTGCGGGCGAATCCGCAGGTGCGCGAGAAGGTAGT
GGCGGTCTATGCCGAAGCCGAACCCTTCGTGCCGTCCGAAAACGTCGACGCCCAGCTGTACAATGGGTTCTTTAGCGATG
CCGACCGCGCGGCGATGAAAATCGTGCTGGAAACCGAACCGCGCAATCTGCCGGCGCTGGATATCACCTTCGCCGACCAG
CGTATCGAACGCCTGCTGTTTAACTACCGGGCGCGCAACTTCCCCGGCACGCTCGATGAACATGAGCAGCAGCGCTGGTT
AGAGCATCGTCGTCAGGTGTTTACGCCGGCTTTTTTGCAGGCCTATGCCGATGAGCTGCAGATACTGTATCAACAGTATG
CGGATGATAAAGAGAAGCTGGCGCAGCTGAAGGCGCTGTGGCAGTACGCACAGGATATTGTCTGA

Upstream 100 bases:

>100_bases
ATATGACACAGCAGAGGAAGTTGCTTGCCGCGACCCTTCTGATGACCGGGCAAATCGTTTACCATACCGGTCGCACGCCA
CCACGGATAATGAACAGACT

Downstream 100 bases:

>100_bases
TTGGCTGAAATTCCCGGGTTGCGGCTAACGCCTTACCCGGGCTACAAACGATGACCGGGGAGGACGCCTGACCGTAGGCC
CGCGCAAGTGCAGCGCCGCC

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQPQAVMITGITPQEALAKGDNE
ATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGL
PSFRLEHLTVANGIEHQNAHDAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLVHLNKCPVLAQANTLRPQDAD
RLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSENVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQ
RIERLLFNYRARNFPGTLDEHEQQRWLEHRRQVFTPAFLQAYADELQILYQQYADDKEKLAQLKALWQYAQDIV

Sequences:

>Translated_474_residues
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQPQAVMITGITPQEALAKGDNE
ATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGL
PSFRLEHLTVANGIEHQNAHDAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLVHLNKCPVLAQANTLRPQDAD
RLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSENVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQ
RIERLLFNYRARNFPGTLDEHEQQRWLEHRRQVFTPAFLQAYADELQILYQQYADDKEKLAQLKALWQYAQDIV
>Mature_474_residues
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQPQAVMITGITPQEALAKGDNE
ATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGL
PSFRLEHLTVANGIEHQNAHDAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLVHLNKCPVLAQANTLRPQDAD
RLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSENVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQ
RIERLLFNYRARNFPGTLDEHEQQRWLEHRRQVFTPAFLQAYADELQILYQQYADDKEKLAQLKALWQYAQDIV

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=474, Percent_Identity=85.2320675105485, Blast_Score=856, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54129; Mature: 54129

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQP
CCCCCCCCCEEEECHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHCCCC
QAVMITGITPQEALAKGDNEATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFY
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCC
DPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGLPSFRLEHLTVANGIEHQNAH
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHH
DAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECCCCCCCCC
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLV
CCCEEEEEEECCCCCCEEEEEEECCCCHHHHHCCHHHHHHHHCCCCHHHCCCCCCCEEEE
HLNKCPVLAQANTLRPQDADRLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSE
EECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCC
NVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQRIERLLFNYRARNFPGTLDE
CCCHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCH
HEQQRWLEHRRQVFTPAFLQAYADELQILYQQYADDKEKLAQLKALWQYAQDIV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQP
CCCCCCCCCEEEECHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHCCCC
QAVMITGITPQEALAKGDNEATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFY
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCC
DPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGLPSFRLEHLTVANGIEHQNAH
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHH
DAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECCCCCCCCC
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLV
CCCEEEEEEECCCCCCEEEEEEECCCCHHHHHCCHHHHHHHHCCCCHHHCCCCCCCEEEE
HLNKCPVLAQANTLRPQDADRLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSE
EECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCC
NVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQRIERLLFNYRARNFPGTLDE
CCCHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCH
HEQQRWLEHRRQVFTPAFLQAYADELQILYQQYADDKEKLAQLKALWQYAQDIV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]