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The map label for this gene is yyaH [H]

Identifier: 152970566

GI number: 152970566

Start: 2210176

End: 2210559

Strand: Direct

Name: yyaH [H]

Synonym: KPN_02017

Alternate gene names: 152970566

Gene position: 2210176-2210559 (Clockwise)

Preceding gene: 152970564

Following gene: 152970567

Centisome position: 41.58

GC content: 59.9

Gene sequence:

>384_bases
ATGAAAATTGCCCATTTCGCCCTGTGGACCCAACAGCTCGACGTCCAGGCCCGCTTCTGGGTGGACTTCTTTGCCGCCAG
CATCAATGAAAAATACCTTAGCCAGACCAACCCCGGCTTTGCCTCCTATTTCGTTACTATCGACGATGAGGTGGTGATAG
AGCTGATGACCAAGCCTGGCCTGCAGCAGGCCAGCGCGGATAATAACCATACCGGCTGGGCGCATCTGGCCCTCTCGGTG
GGCGGGGCGGAACAGGTCGATGCCATCGCCCAACGCGCCGGGGCCGCCGGAATACTGATTTCGCCGCCGCGCACCACCGG
CGACGGCTATTATGAGGCGGTGATCGCCGATCCCGATGGCAACCTGATCGAAATCGTCGCATAG

Upstream 100 bases:

>100_bases
AATCGAGCACGAAAACTCCTTAAATTATCAAAAACGAGCAACAGCAAGCATGATCGTCTGCGCTGCTTTGATTGTCAATG
TTCCTGCCCGGAGGTTTACC

Downstream 100 bases:

>100_bases
TCAGCAGAACGCCAGTATTCAGGAGGCATCCATGGCACATTACCGGATTATCGACACCGCATCCTGGCCCCGCCGGGACC
ATTTCACTTTTTACCGCCAA

Product: glyoxalase I, nickel isomerase

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPGLQQASADNNHTGWAHLALSV
GGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDGNLIEIVA

Sequences:

>Translated_127_residues
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPGLQQASADNNHTGWAHLALSV
GGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDGNLIEIVA
>Mature_127_residues
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPGLQQASADNNHTGWAHLALSV
GGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDGNLIEIVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 13724; Mature: 13724

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPG
CCEEHHEEEHHHCCCCHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCEEEEECCCCC
LQQASADNNHTGWAHLALSVGGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDG
CCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCC
NLIEIVA
CEEEEEC
>Mature Secondary Structure
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPG
CCEEHHEEEHHHCCCCHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCEEEEECCCCC
LQQASADNNHTGWAHLALSVGGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDG
CCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCC
NLIEIVA
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]