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The map label for this gene is rhtC [H]

Identifier: 152970564

GI number: 152970564

Start: 2208681

End: 2209310

Strand: Direct

Name: rhtC [H]

Synonym: KPN_02015

Alternate gene names: 152970564

Gene position: 2208681-2209310 (Clockwise)

Preceding gene: 152970562

Following gene: 152970566

Centisome position: 41.55

GC content: 62.54

Gene sequence:

>630_bases
ATGTTCCTATCCAGCCTGATGGCCATTGCCGCGGTGCTGATCATGGGCGTGATCAGTCCCGGCCCAAGCTTTATCTTTGT
TGCGCGCAATGCCGTCGCTCGCTCGCGTCTGCACGGTATGGTGACCGCCCTCGGTACCGGCGCCGGTGCGGCCATTTTCT
CCATTATGGCGATGCTGGGCCTGCAGAAGGTGCTCACCGCGGTGCCGGAGCTGTTTATTGGTTTGAAGGTGGCGGGCGGG
CTCTATCTGCTGTGGCTGGGCTATAAAATTTTTCGCGGGTCGGCGCAGCCGATGGACTTTTCCGCCAGCGGGATGGCCGG
CAACCGCTCTTTGCTGAAGACCTTCCGCGACGGGCTGTATACTCAGCTCAGCAATCCCAAAACTGCGCTGGTGTTCGCCT
CAATTTTTACCGCCCTGCTGCCGGCGCAGATCCCCACCGCCTTCTATTACATCGTGCCGCTGATGAGCTTTCTGATCGAC
GTCAGCTGGTATTCGCTGGTGGCGCTGGTGCTGTCTGCCGACCGCCCGCGCCGCGTCTACCTGCGGCTGAAGCGGCGGAT
CGACATCGCCACCGCGACGGTGCTGGGGGCGCTGGGCCTGCGGCTTATCGCCACCTCCCTCACCCGCTAG

Upstream 100 bases:

>100_bases
CTTTTTGACGTGCTTTCCTGAACCAGTTTGCTACTCTGTCTGCTCCAACCGTCCACACGTTACCGACCGCCTGCCTGCGG
CGGACATAACAGGAGTCGCT

Downstream 100 bases:

>100_bases
CGGGTTACACGGTATAGATGCAAATATCGTGCTGCTGAAAGGCAACGCGATATTCGCGACTGATATTCTCTTCCACCACC
AGCACATCGATATCGCTGCT

Product: amino acid exporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MFLSSLMAIAAVLIMGVISPGPSFIFVARNAVARSRLHGMVTALGTGAGAAIFSIMAMLGLQKVLTAVPELFIGLKVAGG
LYLLWLGYKIFRGSAQPMDFSASGMAGNRSLLKTFRDGLYTQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLID
VSWYSLVALVLSADRPRRVYLRLKRRIDIATATVLGALGLRLIATSLTR

Sequences:

>Translated_209_residues
MFLSSLMAIAAVLIMGVISPGPSFIFVARNAVARSRLHGMVTALGTGAGAAIFSIMAMLGLQKVLTAVPELFIGLKVAGG
LYLLWLGYKIFRGSAQPMDFSASGMAGNRSLLKTFRDGLYTQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLID
VSWYSLVALVLSADRPRRVYLRLKRRIDIATATVLGALGLRLIATSLTR
>Mature_209_residues
MFLSSLMAIAAVLIMGVISPGPSFIFVARNAVARSRLHGMVTALGTGAGAAIFSIMAMLGLQKVLTAVPELFIGLKVAGG
LYLLWLGYKIFRGSAQPMDFSASGMAGNRSLLKTFRDGLYTQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLID
VSWYSLVALVLSADRPRRVYLRLKRRIDIATATVLGALGLRLIATSLTR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=32.5, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786522, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22507; Mature: 22507

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSSLMAIAAVLIMGVISPGPSFIFVARNAVARSRLHGMVTALGTGAGAAIFSIMAMLG
CHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LQKVLTAVPELFIGLKVAGGLYLLWLGYKIFRGSAQPMDFSASGMAGNRSLLKTFRDGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLIDVSWYSLVALVLSADRPRRVY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LRLKRRIDIATATVLGALGLRLIATSLTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLSSLMAIAAVLIMGVISPGPSFIFVARNAVARSRLHGMVTALGTGAGAAIFSIMAMLG
CHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LQKVLTAVPELFIGLKVAGGLYLLWLGYKIFRGSAQPMDFSASGMAGNRSLLKTFRDGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLIDVSWYSLVALVLSADRPRRVY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LRLKRRIDIATATVLGALGLRLIATSLTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]