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The map label for this gene is ydhC [H]

Identifier: 152970550

GI number: 152970550

Start: 2192857

End: 2194092

Strand: Direct

Name: ydhC [H]

Synonym: KPN_01998

Alternate gene names: 152970550

Gene position: 2192857-2194092 (Clockwise)

Preceding gene: 152970548

Following gene: 152970551

Centisome position: 41.26

GC content: 62.06

Gene sequence:

>1236_bases
ATGCACTCCCTACACTCTGCGGCATCGTACCTGTACACCAACTATGAGAACGTTATGTCACAACCCGGGAAAGGATTTTT
AGTCTGGCTGGCCGGCCTGAGCGTGCTGGGCTTTCTGGCCACCGATATGTACCTGCCGGCGTTTGCCGCCATGCAGCAGG
ATCTCAACACCTCCGCCGCCTCCATTAGCGCCAGCCTGAGCCTGTTCCTCGCCGGCTTCGCGCTGGGCCAGCTGTTCTGG
GGACCGCTGTCGGACCGCTATGGACGTAAACCGGTGCTGCTGAGCGGCCTGGCGATTTTCGCGGCCGGCTGTCTGGGGAT
GCTGTGGGTGCACAACGCCACCCTGATGCTGGCGCTGCGCTTTCTGCAGGCGATTGGCGTCTGTGCCGCGGCCGTTACCT
GGCAGGCGATGGTCGCCGATTACTATCCTGCCCAGCGCACGAACCGCATCTTCGCCACCATTATGCCGCTGGTAGGACTG
TCGCCGGCGCTGGCCCCGCTGCTGGGCAGCTGGCTGCTGGTGCACTTCGAGTGGCAAGCCATCTTCGCCACCCTGTTCGC
CATCACTCTGCTGCTGATGCTGCCTGCCCTGCGCCTGAAGGCAGCCGCGAAGTCAGTAGTAGTGACGCAGCAAAAGATCA
CCTTTCTCGCGCTGCTGCGCTCCCGGGAATACAGCGGCAACGTCCTGATCTACGCCGCCTGTTCCGCCAGCTTCTTCGCC
TGGCTTACCGGTTCACCTTTTATCCTGCATGAAATGGGCTATGGCCCAACCGCTATCGGCCTGAGCTATATTCCGCAGAC
CATCGCCTTTCTGGTGGGAGGCTATGGCTGTCGCGCGCTGCTGCAGAAATGGTCCGGTCAACAGATGCTGCCGTGGCTGC
TGGTGATTTTTGCCGTCAGCGTAGCCGCCACCTGGCTGGTGGGCCTGCAAACCCATGCCTCGCTGGTGGCGTTAATGATC
CCGTTCTGCATGATGGCGGTGGTCAACGGCGGGATCTACCCCATCGTGGTTGCTCAGGCGCTGAAGCCTTTTCCGCAGGC
GACCGGCCGCGCGGCGGCGCTGCAAAATACCCTGCAGCTTGGCCTGTGCTTCCTGACCAGTCTGCTGGTATCCGCGCTGA
TCGCCACGCCGCTGCTGACCACCACCAGCGTAATGCTGGTTTCGATTGGCTTAGCCGGAATAGGCTATCGCCTGCAGCAG
ACGCCGGAGCTGACACCCCACTCTTCCCACGCGTAA

Upstream 100 bases:

>100_bases
GGCGACGGCATCAACCACTTCCAGAGAGTATTCAGACCACATTTTCTGCCTGCAAAATTTTTGAATGCATGTGACAAATA
TTAGCGTTTCACAAGCCACA

Downstream 100 bases:

>100_bases
TGCCCGTCGCCAGGGCCCGGACCAGTCGTTAGCATGCTAAGAAATTTTTATTGAAAGCCAGTACTTAGCGTCCTATACTG
GATCCGGGTTCACATAAATA

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MHSLHSAASYLYTNYENVMSQPGKGFLVWLAGLSVLGFLATDMYLPAFAAMQQDLNTSAASISASLSLFLAGFALGQLFW
GPLSDRYGRKPVLLSGLAIFAAGCLGMLWVHNATLMLALRFLQAIGVCAAAVTWQAMVADYYPAQRTNRIFATIMPLVGL
SPALAPLLGSWLLVHFEWQAIFATLFAITLLLMLPALRLKAAAKSVVVTQQKITFLALLRSREYSGNVLIYAACSASFFA
WLTGSPFILHEMGYGPTAIGLSYIPQTIAFLVGGYGCRALLQKWSGQQMLPWLLVIFAVSVAATWLVGLQTHASLVALMI
PFCMMAVVNGGIYPIVVAQALKPFPQATGRAAALQNTLQLGLCFLTSLLVSALIATPLLTTTSVMLVSIGLAGIGYRLQQ
TPELTPHSSHA

Sequences:

>Translated_411_residues
MHSLHSAASYLYTNYENVMSQPGKGFLVWLAGLSVLGFLATDMYLPAFAAMQQDLNTSAASISASLSLFLAGFALGQLFW
GPLSDRYGRKPVLLSGLAIFAAGCLGMLWVHNATLMLALRFLQAIGVCAAAVTWQAMVADYYPAQRTNRIFATIMPLVGL
SPALAPLLGSWLLVHFEWQAIFATLFAITLLLMLPALRLKAAAKSVVVTQQKITFLALLRSREYSGNVLIYAACSASFFA
WLTGSPFILHEMGYGPTAIGLSYIPQTIAFLVGGYGCRALLQKWSGQQMLPWLLVIFAVSVAATWLVGLQTHASLVALMI
PFCMMAVVNGGIYPIVVAQALKPFPQATGRAAALQNTLQLGLCFLTSLLVSALIATPLLTTTSVMLVSIGLAGIGYRLQQ
TPELTPHSSHA
>Mature_411_residues
MHSLHSAASYLYTNYENVMSQPGKGFLVWLAGLSVLGFLATDMYLPAFAAMQQDLNTSAASISASLSLFLAGFALGQLFW
GPLSDRYGRKPVLLSGLAIFAAGCLGMLWVHNATLMLALRFLQAIGVCAAAVTWQAMVADYYPAQRTNRIFATIMPLVGL
SPALAPLLGSWLLVHFEWQAIFATLFAITLLLMLPALRLKAAAKSVVVTQQKITFLALLRSREYSGNVLIYAACSASFFA
WLTGSPFILHEMGYGPTAIGLSYIPQTIAFLVGGYGCRALLQKWSGQQMLPWLLVIFAVSVAATWLVGLQTHASLVALMI
PFCMMAVVNGGIYPIVVAQALKPFPQATGRAAALQNTLQLGLCFLTSLLVSALIATPLLTTTSVMLVSIGLAGIGYRLQQ
TPELTPHSSHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=386, Percent_Identity=74.6113989637306, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1788509, Length=343, Percent_Identity=26.2390670553936, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790146, Length=217, Percent_Identity=30.8755760368664, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790794, Length=231, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082312, Length=338, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787065, Length=217, Percent_Identity=26.2672811059908, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44099; Mature: 44099

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLHSAASYLYTNYENVMSQPGKGFLVWLAGLSVLGFLATDMYLPAFAAMQQDLNTSAA
CCCHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
SISASLSLFLAGFALGQLFWGPLSDRYGRKPVLLSGLAIFAAGCLGMLWVHNATLMLALR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQAIGVCAAAVTWQAMVADYYPAQRTNRIFATIMPLVGLSPALAPLLGSWLLVHFEWQA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IFATLFAITLLLMLPALRLKAAAKSVVVTQQKITFLALLRSREYSGNVLIYAACSASFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHH
WLTGSPFILHEMGYGPTAIGLSYIPQTIAFLVGGYGCRALLQKWSGQQMLPWLLVIFAVS
HHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
VAATWLVGLQTHASLVALMIPFCMMAVVNGGIYPIVVAQALKPFPQATGRAAALQNTLQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
GLCFLTSLLVSALIATPLLTTTSVMLVSIGLAGIGYRLQQTPELTPHSSHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]