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The map label for this gene is cfa [H]

Identifier: 152970551

GI number: 152970551

Start: 2194535

End: 2195533

Strand: Direct

Name: cfa [H]

Synonym: KPN_01999

Alternate gene names: 152970551

Gene position: 2194535-2195533 (Clockwise)

Preceding gene: 152970550

Following gene: 152970553

Centisome position: 41.29

GC content: 54.35

Gene sequence:

>999_bases
TTGCAGGAAGGTTCGCTGGGTTTAGGCGAAAGCTATATGGACGGCTGGTGGGAATGCGAGCGTCTGGATATATTCTTCCA
CAAGGTGTTACGCGCCGGGTTGGAAAAGCAGCTCCCACACCATTTCAAAGACACACTCCGCATCGCAGGCGCTCGTCTGT
TTAATCTACAAAGTAAAAAACGTGCCTGGATTGTCGGTAAAGAGCACTACGACCTCGGCAACGATCTATTCAGCCGGATG
CTTGATCCCTATATGCAATATTCCTGCGGTTACTGGAAAGAGGCGCAGAGCCTCGAGGCCGCCCAGCAGGCTAAGCTGGA
TCTCATCTGCCGCAAACTGGAGCTGGAGCCAGGCATGCGGGTACTGGATATTGGCTGTGGATGGGGCGGTCTCGCCGAAT
ATATGGCGCGAAATTATCAGGTCAGCGTCGTGGGTGTAACCATCTCCGCCGAGCAACAAAAAATGGCCCAGGCGCGCTGC
GCCGATCTCGATGTAGAGATTCGTCTCCAGGATTATCGCGATCTGCACGACAGCTTTGACCGCATCGTCTCCGTTGGCAT
GTTTGAGCACGTGGGGCCGAAAAATTACGCCACCTACTTTGAGGTTGCCGACCGTAATTTGAAACCCAACGGCCGCTTTT
TACTGCACACCATTGGTTCCAAGGTCACCGACCATAACGTTGACCCGTGGATCGATAAATATATCTTCCCGAACGGCTGC
CTGCCTTCCGTGCGTCACATTGCCGAAGCCAGCGAGAAGCATTTTGTGATGGAAGACTGGCACAACTTCGGCGCTGATTA
CGACACGACCCTGATGGCCTGGTATGAGCGTTTCCTCGCCAGCTGGCCGGAAATTGCCGATAACTATTCTGAGCGTTTCA
AACGCATGTTTACCTATTATCTGAACGCCTGCGCCGGCGCCTTCCGCGCCCGCGACATTCAGCTCTGGCAGGTGGTGTTC
TCGCGCGGTATTGAACATGGACTGCGCGTCGCCCGTTAA

Upstream 100 bases:

>100_bases
CCGGATTGCAGCTGAATTATTAGGCCGTGCGGGAATTGAAATCAATGGCTCCGCGCCGTCCGACCTGCGGGTTAAAAATC
CTCTCTTTTTTAAACGGGTT

Downstream 100 bases:

>100_bases
ATAACACTCCCCCGCTTATCGGCGGGGGATTTTTTTTCAGGCTTCATTGACCTTAGCCGCCATCTCTTTCGCGGCCAGCA
CGCGTTCGACCGTATCGACA

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQEGSLGLGESYMDGWWECERLDIFFHKVLRAGLEKQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRM
LDPYMQYSCGYWKEAQSLEAAQQAKLDLICRKLELEPGMRVLDIGCGWGGLAEYMARNYQVSVVGVTISAEQQKMAQARC
ADLDVEIRLQDYRDLHDSFDRIVSVGMFEHVGPKNYATYFEVADRNLKPNGRFLLHTIGSKVTDHNVDPWIDKYIFPNGC
LPSVRHIAEASEKHFVMEDWHNFGADYDTTLMAWYERFLASWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVF
SRGIEHGLRVAR

Sequences:

>Translated_332_residues
MQEGSLGLGESYMDGWWECERLDIFFHKVLRAGLEKQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRM
LDPYMQYSCGYWKEAQSLEAAQQAKLDLICRKLELEPGMRVLDIGCGWGGLAEYMARNYQVSVVGVTISAEQQKMAQARC
ADLDVEIRLQDYRDLHDSFDRIVSVGMFEHVGPKNYATYFEVADRNLKPNGRFLLHTIGSKVTDHNVDPWIDKYIFPNGC
LPSVRHIAEASEKHFVMEDWHNFGADYDTTLMAWYERFLASWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVF
SRGIEHGLRVAR
>Mature_332_residues
MQEGSLGLGESYMDGWWECERLDIFFHKVLRAGLEKQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRM
LDPYMQYSCGYWKEAQSLEAAQQAKLDLICRKLELEPGMRVLDIGCGWGGLAEYMARNYQVSVVGVTISAEQQKMAQARC
ADLDVEIRLQDYRDLHDSFDRIVSVGMFEHVGPKNYATYFEVADRNLKPNGRFLLHTIGSKVTDHNVDPWIDKYIFPNGC
LPSVRHIAEASEKHFVMEDWHNFGADYDTTLMAWYERFLASWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVF
SRGIEHGLRVAR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=332, Percent_Identity=87.6506024096386, Blast_Score=620, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI133904226, Length=362, Percent_Identity=29.5580110497238, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 38593; Mature: 38593

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEGSLGLGESYMDGWWECERLDIFFHKVLRAGLEKQLPHHFKDTLRIAGARLFNLQSKK
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
RAWIVGKEHYDLGNDLFSRMLDPYMQYSCGYWKEAQSLEAAQQAKLDLICRKLELEPGMR
CEEEECCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLDIGCGWGGLAEYMARNYQVSVVGVTISAEQQKMAQARCADLDVEIRLQDYRDLHDSFD
EEEECCCCHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
RIVSVGMFEHVGPKNYATYFEVADRNLKPNGRFLLHTIGSKVTDHNVDPWIDKYIFPNGC
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCC
LPSVRHIAEASEKHFVMEDWHNFGADYDTTLMAWYERFLASWPEIADNYSERFKRMFTYY
CHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LNACAGAFRARDIQLWQVVFSRGIEHGLRVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQEGSLGLGESYMDGWWECERLDIFFHKVLRAGLEKQLPHHFKDTLRIAGARLFNLQSKK
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
RAWIVGKEHYDLGNDLFSRMLDPYMQYSCGYWKEAQSLEAAQQAKLDLICRKLELEPGMR
CEEEECCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLDIGCGWGGLAEYMARNYQVSVVGVTISAEQQKMAQARCADLDVEIRLQDYRDLHDSFD
EEEECCCCHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
RIVSVGMFEHVGPKNYATYFEVADRNLKPNGRFLLHTIGSKVTDHNVDPWIDKYIFPNGC
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCC
LPSVRHIAEASEKHFVMEDWHNFGADYDTTLMAWYERFLASWPEIADNYSERFKRMFTYY
CHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LNACAGAFRARDIQLWQVVFSRGIEHGLRVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]