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The map label for this gene is 152970361

Identifier: 152970361

GI number: 152970361

Start: 1997748

End: 1998767

Strand: Direct

Name: 152970361

Synonym: KPN_01809

Alternate gene names: NA

Gene position: 1997748-1998767 (Clockwise)

Preceding gene: 152970356

Following gene: 152970362

Centisome position: 37.59

GC content: 57.75

Gene sequence:

>1020_bases
ATGGCGATTTTTGATGGTCACAATGACCTGCTGCTGAATCTCTGGCTTCACCATCGCGAGGATCCGGTGAGCGCCTTCTT
TGCCGGGATTGAGAACGGCCATCTCGACTATCCGCGCATGCTGCAAGGCGGATTTGCCGGCGGGCTATTCGCGCTATTCG
TGCCACCGCAGGAATATATTGCCCGTATGACGCCGCAATACGCCAGCCAACGATGGGATCCGATCGATATCCTCTGGCAG
CAACTGGCCATCCTGAAGCAACTTATCGCGCACTCCGCTGGACGCTTGAGATTGTGTCTGAGCGCGGCGGATATCGAACG
CTGCCGCGAGGATAAGGTACTGGCGATGGTGGCGCATATTGAGGGTGCCGGAGGTTTTGATGGCGAGGGCCGCGACCTGC
AGGCCTTTTATGCCGCCGGGGTCCGCAGCATTGGTCCGTTCTGGAATATTGCGAACCGCTTCGGCAGCGGCGTTAACGGT
TCGTTTCCCGGTAGCCCGGACACTGGGCCTGGACTGACAGCGGCAGGTATCGATCTGATTAAGCAGGCCAATGCCTTGAA
GATGCAGATTGACGTGTCTCATATGAATGAAAAAGCGTTCTGGGATACCGCCCATCACTCAACGTCACCGCTGGTGGCCA
CCCACTCCAATGCCCACGCCCTGTGCCCGCAGCCGCGCAATCTGACCGACCAGCAACTGCGGGCGATCCGCGACAGCGGC
GGCGTGGTGGGCGTCAATTTCGGCAATGCTTTCCTGCGCGCCGACGGCCGGCGCGATAGCGACACGCCCTTAACCACCAT
TGTCCGGCATATCGACTATCTTATTAACATAATGGGTGAGGATCATGTGGCTCTTGGCTCGGATTTTGACGGCATCACCC
TGCCGGACGAGCTGGGCGATGTGGCCGGCTTACCGCGGCTTATCAATACGTTGCGCGCTAGCGGCTATGATCAATTGGTG
CTGGATAAGCTGCTGTGGCGTAACTGGCTACGGGTATTAAAAAATGTTTGGCAACAATAG

Upstream 100 bases:

>100_bases
TTGGCAATTGTTGCGGGCATGTGAATTTATGCTTGCCCCGGGAGATAAATCCGTTACCGTGGCAGGCATTTTTCACCACT
TAAGAACGCAGGAACCCGCT

Downstream 100 bases:

>100_bases
GTTATATTGTAAACATAAAGTTAATTCCTTACAGATTCCGGGTTGATCTCTCTCCCGGTGAAGCGCAATATGCGGCAGCC
GTCACAGATCCACCATTATC

Product: proline dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQ
QLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNG
SFPGSPDTGPGLTAAGIDLIKQANALKMQIDVSHMNEKAFWDTAHHSTSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLV
LDKLLWRNWLRVLKNVWQQ

Sequences:

>Translated_339_residues
MAIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQ
QLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNG
SFPGSPDTGPGLTAAGIDLIKQANALKMQIDVSHMNEKAFWDTAHHSTSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLV
LDKLLWRNWLRVLKNVWQQ
>Mature_338_residues
AIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQQ
LAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGS
FPGSPDTGPGLTAAGIDLIKQANALKMQIDVSHMNEKAFWDTAHHSTSPLVATHSNAHALCPQPRNLTDQQLRAIRDSGG
VVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLVL
DKLLWRNWLRVLKNVWQQ

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=341, Percent_Identity=26.099706744868, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4758190, Length=341, Percent_Identity=26.099706744868, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI11641269, Length=341, Percent_Identity=25.5131964809384, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI193211608, Length=335, Percent_Identity=24.7761194029851, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI193211610, Length=335, Percent_Identity=24.7761194029851, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221475880, Length=346, Percent_Identity=28.9017341040462, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281362638, Length=346, Percent_Identity=26.878612716763, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281362636, Length=346, Percent_Identity=26.878612716763, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI161083233, Length=346, Percent_Identity=26.878612716763, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 37361; Mature: 37230

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYI
CEEECCCCCEEEHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEECCHHHH
ARMTPQYASQRWDPIDILWQQLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHI
HHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEEEEEE
EGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGSFPGSPDTGPGLTAAGIDLI
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
KQANALKMQIDVSHMNEKAFWDTAHHSTSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
HCCCCEEEEEEHHHCCCHHHHCCCCCCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHCC
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGD
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
VAGLPRLINTLRASGYDQLVLDKLLWRNWLRVLKNVWQQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIFDGHNDLLLNLWLHHREDPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYI
EEECCCCCEEEHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEECCHHHH
ARMTPQYASQRWDPIDILWQQLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHI
HHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEEEEEE
EGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGSFPGSPDTGPGLTAAGIDLI
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
KQANALKMQIDVSHMNEKAFWDTAHHSTSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
HCCCCEEEEEEHHHCCCHHHHCCCCCCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHCC
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGD
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
VAGLPRLINTLRASGYDQLVLDKLLWRNWLRVLKNVWQQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]