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The map label for this gene is gap [H]

Identifier: 152970262

GI number: 152970262

Start: 1890345

End: 1891355

Strand: Direct

Name: gap [H]

Synonym: KPN_01710

Alternate gene names: 152970262

Gene position: 1890345-1891355 (Clockwise)

Preceding gene: 152970261

Following gene: 152970263

Centisome position: 35.57

GC content: 53.02

Gene sequence:

>1011_bases
ATGGTAAAGGTCGGTATTAACGGTTTTGGCCGGATCGGACGCAATGTACTGCGCGCAGCACTGAATAATCCGGATATTCA
AATTGTGGCAATCAACGATTTGACGGACAGCAAAACGCTGGCGCATCTGCTGAAATACGACTCGCTTCTCGGTAAGCTGG
ATGCAGAGGTCACCGCGGGTGAAGGGGGGCTTGTTGTTGATGGTAAACCCATTACCGTATTCAGTGAACGCAACCCGGCC
AGTATTCCGTGGCGTCAGTGTGAAGTCGACATCGTTATTGAGGCTACAGGATTATTCACGGACCGTGAAAAGGCTGCTGT
ACATATCCACAGCGGTGGCGCCAAGCGCGTGATTATCTCTGCCCCGGGTAAAAACGATGATTTAACCATTGTGATGGGCG
TTAATGAGAGCCTTTACTCCCCGGATAAACACTACGTGATCAGCAACGGAAGCTGCACCACCAATGGTCTTGCACCTGCT
GCGCAGGTCCTGCACCAGCATTTCGGTATTAAACATGGTCTCATGAACACCACCCATGCCTACACCAACAGCCAGGCGCT
GCACGATCAGCCGGAAAAAGATCTGCGCGGGGCTCGTGCCGCCGCATTGTCGATTGTGCCTTACTCCAGCGGCGCAGCGA
AGGCTCTGGGTAAAGTTATTCCTGAGCTGGATGGGCGTTTAACGGGATACTCGCTACGCGTCCCTGTGCCAGTGGTGTCC
ATTGTTGACCTCACCGTCACGCTTGAGCGAGATGTGACGGTCGAAGAGGTGAACAATGCTTTTCGCGAAGCCGCCGCAGC
GGGACCTCTGAAAGGGATCCTGGGTTATAGCGATGAACCGCTCGTCTCCAGCGATTACCAGGGAGACCCACGCTCGTCGA
TTATCGACGGTCTATCAACGCTGGTGATTGGCGGTAATATGGTCAAAATTCTGGCGTGGTACGACAATGAATGGGGATTC
TCTAATCGTCTCGTTGATCTGGCATTGATGATGGCAAAGCGTGAAAGCTAA

Upstream 100 bases:

>100_bases
TCACTGTCGCAAAATGGCGTAAAGTGATCCTTTTTTGTCATTTACGCCATAACCCGTCCGTCCTACTCTGACTCCAGCGA
TAATCGATAAGGAGTTAATT

Downstream 100 bases:

>100_bases
GCCACTGTCGCTGTATTCATCTGTAAAAGTATAAGCAGTTCAGCTGGATGAATAGTGGCTCGAGTATCATTCATAGATGA
AACATAACAAATCTTTCTGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVKVGINGFGRIGRNVLRAALNNPDIQIVAINDLTDSKTLAHLLKYDSLLGKLDAEVTAGEGGLVVDGKPITVFSERNPA
SIPWRQCEVDIVIEATGLFTDREKAAVHIHSGGAKRVIISAPGKNDDLTIVMGVNESLYSPDKHYVISNGSCTTNGLAPA
AQVLHQHFGIKHGLMNTTHAYTNSQALHDQPEKDLRGARAAALSIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
IVDLTVTLERDVTVEEVNNAFREAAAAGPLKGILGYSDEPLVSSDYQGDPRSSIIDGLSTLVIGGNMVKILAWYDNEWGF
SNRLVDLALMMAKRES

Sequences:

>Translated_336_residues
MVKVGINGFGRIGRNVLRAALNNPDIQIVAINDLTDSKTLAHLLKYDSLLGKLDAEVTAGEGGLVVDGKPITVFSERNPA
SIPWRQCEVDIVIEATGLFTDREKAAVHIHSGGAKRVIISAPGKNDDLTIVMGVNESLYSPDKHYVISNGSCTTNGLAPA
AQVLHQHFGIKHGLMNTTHAYTNSQALHDQPEKDLRGARAAALSIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
IVDLTVTLERDVTVEEVNNAFREAAAAGPLKGILGYSDEPLVSSDYQGDPRSSIIDGLSTLVIGGNMVKILAWYDNEWGF
SNRLVDLALMMAKRES
>Mature_336_residues
MVKVGINGFGRIGRNVLRAALNNPDIQIVAINDLTDSKTLAHLLKYDSLLGKLDAEVTAGEGGLVVDGKPITVFSERNPA
SIPWRQCEVDIVIEATGLFTDREKAAVHIHSGGAKRVIISAPGKNDDLTIVMGVNESLYSPDKHYVISNGSCTTNGLAPA
AQVLHQHFGIKHGLMNTTHAYTNSQALHDQPEKDLRGARAAALSIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
IVDLTVTLERDVTVEEVNNAFREAAAAGPLKGILGYSDEPLVSSDYQGDPRSSIIDGLSTLVIGGNMVKILAWYDNEWGF
SNRLVDLALMMAKRES

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=50, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=47.0059880239521, Blast_Score=297, Evalue=1e-80,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=49.2492492492492, Blast_Score=323, Evalue=9e-90,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=42.3880597014925, Blast_Score=272, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=49.112426035503, Blast_Score=309, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=48.8165680473373, Blast_Score=309, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=46.6076696165192, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=46.6076696165192, Blast_Score=286, Evalue=7e-78,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=48.0597014925373, Blast_Score=314, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=46.2686567164179, Blast_Score=313, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=47.4626865671642, Blast_Score=310, Evalue=2e-85,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=50.1483679525223, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=50.1483679525223, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=49.5548961424332, Blast_Score=309, Evalue=1e-84,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=49.5548961424332, Blast_Score=309, Evalue=1e-84,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=45.619335347432, Blast_Score=279, Evalue=2e-75,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35972; Mature: 35972

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVGINGFGRIGRNVLRAALNNPDIQIVAINDLTDSKTLAHLLKYDSLLGKLDAEVTAG
CEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECC
EGGLVVDGKPITVFSERNPASIPWRQCEVDIVIEATGLFTDREKAAVHIHSGGAKRVIIS
CCCEEECCCEEEEEECCCCCCCCHHHEEEEEEEEECCCEECCCCEEEEEECCCCCEEEEE
APGKNDDLTIVMGVNESLYSPDKHYVISNGSCTTNGLAPAAQVLHQHFGIKHGLMNTTHA
CCCCCCCEEEEEECCHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCC
YTNSQALHDQPEKDLRGARAAALSIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
CCCCCHHCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEE
IVDLTVTLERDVTVEEVNNAFREAAAAGPLKGILGYSDEPLVSSDYQGDPRSSIIDGLST
EEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
LVIGGNMVKILAWYDNEWGFSNRLVDLALMMAKRES
EEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKVGINGFGRIGRNVLRAALNNPDIQIVAINDLTDSKTLAHLLKYDSLLGKLDAEVTAG
CEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECC
EGGLVVDGKPITVFSERNPASIPWRQCEVDIVIEATGLFTDREKAAVHIHSGGAKRVIIS
CCCEEECCCEEEEEECCCCCCCCHHHEEEEEEEEECCCEECCCCEEEEEECCCCCEEEEE
APGKNDDLTIVMGVNESLYSPDKHYVISNGSCTTNGLAPAAQVLHQHFGIKHGLMNTTHA
CCCCCCCEEEEEECCHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCC
YTNSQALHDQPEKDLRGARAAALSIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
CCCCCHHCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEE
IVDLTVTLERDVTVEEVNNAFREAAAAGPLKGILGYSDEPLVSSDYQGDPRSSIIDGLST
EEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
LVIGGNMVKILAWYDNEWGFSNRLVDLALMMAKRES
EEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]