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The map label for this gene is xylB [H]

Identifier: 152970255

GI number: 152970255

Start: 1883615

End: 1885120

Strand: Direct

Name: xylB [H]

Synonym: KPN_01703

Alternate gene names: 152970255

Gene position: 1883615-1885120 (Clockwise)

Preceding gene: 152970254

Following gene: 152970256

Centisome position: 35.44

GC content: 58.7

Gene sequence:

>1506_bases
ATGAAAGATAAAATACTCACGATTGATGTTGGCACTGGCAGTACCCGCGCCGCTATTGTGCGCATTGACGGCGCGATGAT
CGGCTTTGCGCAAAGAGAGTATGAGCAAACCACGCCGCGTGCAGGTTGGTCAGAACAGGCCCCGTCTTTATGGTGGCAGG
CCGCCTGCGACTGTATACGCGAGGTGCTTTACCGCTATCCTGAAACGGCAGCGCAAATTGCGGTTATTGGTGCTTGCGGA
CAGATGCATGGCACCGTCCTTCTGGACGACCGTGGCGAGCTGGTGGAGGATAGGGCGTTGCTGTGGAATGATAAGCGCAG
CCAGCCGCAAGTTGACGCCTTTAACGCGCGCGAAGGTTGGGAAAAGTGGCTGGCGCATTTGAATAATCCGCCTGCGGCAG
CATGGCCCGCTTTCAAGTTAGCCTGGTGGCGCGAAAATCATCCGGATCGCTGGTCGCAGCTCGCCAAAGTATTAATGCCG
AAGGACTATATTAATTTCATGCTGACCGGTGCCATGGCGACCGATTATAGCGAAGCGTCGTGCTATTTCCTGATGGACAG
CGAAACCCGTAGCTGGTCTTCGCAAGCCTGCGAAACGTTTGGTCTGCGGGTCGATCAGCTCCCGGAGCTTAAACTTTCCA
GCGACATAATCGGCCAGGTGACGCAGCCCGCAGCCGACCTGACGGGCCTGCCGGCGGGTATCCCGGTGGTTGCCGGGACG
TCGGATATGGCGGCCTCTCTGCTGGGCTCGGGTGTGTATGAACCGGGGATGGCGTCTGATTCAACCGGCACGTCGACGCT
GATGACGGTGGTGTCGCCGCGGCCGTTACACCATCCGCTGGTTAATAATCTACATCTTGCCAACGCGGCCTGGGGCGGAT
TTACGATCCTCGACGCCGGCGGCGATGCCGTTCGCTGGGCGCGGCTGGCACTTGCCGATAACCAGATTACGCATCCACAG
CTTTTACAGGAAGCGGCGGCGGTGCCGGCGGGGGCAGAAGGGCTGCTGTTTCTTCCCTATCTGACGGGAGAACGTCTGGC
CGAACACACGAACTCGCGGGCACAGTTTTTTGGCCTGCAGCGCAAGCATCGCCGCGGTCATTTATTCCGCGCCGTTCTGG
AAGGGGTGGCCTTTGCATCCTGGCGCAATCTTCGGCAGCTGCAGAAGTGCGGGCAGTATCCGCAACAAATGATCGCTTCC
GGCGGCGGCGCGCGCAGCTCGCTGTGGCTTGAAATCAAAGCCTCGGCGTACAATCTGCCGATATTATCTACGCGTAATCA
GGAGAATGGCGTCACCGGATGCGGTATTATCGCCGGGGTTGGCGTAGGGTTGTACGCCGATTTTGCCAGCGGCGTGCGGC
AAACGGTGCAGTTCGAAAAACTGATCTCACCGGATCCCCTTCTGCGGGATTATTACCACGCCTGCTGCGAGCTTTTTGAT
ACGCTGTACCGGCAATCCGCTGCCTTATACGACAGGCTGGATGCGCTCAGCGTAGGACCCGACTGA

Upstream 100 bases:

>100_bases
AACTGGAGCAGCACCCGGAACGTTTTCCCGAGCTGAACGCCGATTAAACTGAGAGACCGCGGGCCTGGTGGCCCGCCTTA
AGACGTCACCGGAGTTAGTG

Downstream 100 bases:

>100_bases
TACGCAAAGGTAAGCCAGCGCCGCGACGCGCGTAACGAGCTGTAAAAAAGAGAGAGGCAGAATGTTTGCAGAAGAAAGAC
AGGAGAAGTTACTCGGTATT

Product: putative pentose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIREVLYRYPETAAQIAVIGACG
QMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMP
KDYINFMLTGAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQPAADLTGLPAGIPVVAGT
SDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAGGDAVRWARLALADNQITHPQ
LLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIAS
GGGARSSLWLEIKASAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFEKLISPDPLLRDYYHACCELFD
TLYRQSAALYDRLDALSVGPD

Sequences:

>Translated_501_residues
MKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIREVLYRYPETAAQIAVIGACG
QMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMP
KDYINFMLTGAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQPAADLTGLPAGIPVVAGT
SDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAGGDAVRWARLALADNQITHPQ
LLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIAS
GGGARSSLWLEIKASAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFEKLISPDPLLRDYYHACCELFD
TLYRQSAALYDRLDALSVGPD
>Mature_501_residues
MKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIREVLYRYPETAAQIAVIGACG
QMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMP
KDYINFMLTGAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQPAADLTGLPAGIPVVAGT
SDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAGGDAVRWARLALADNQITHPQ
LLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIAS
GGGARSSLWLEIKASAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFEKLISPDPLLRDYYHACCELFD
TLYRQSAALYDRLDALSVGPD

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=458, Percent_Identity=23.5807860262009, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI189409120, Length=458, Percent_Identity=23.5807860262009, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4504007, Length=458, Percent_Identity=23.5807860262009, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI41393575, Length=440, Percent_Identity=23.4090909090909, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI88196792, Length=503, Percent_Identity=21.272365805169, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1787789, Length=520, Percent_Identity=29.4230769230769, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789987, Length=492, Percent_Identity=29.8780487804878, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790005, Length=502, Percent_Identity=25.4980079681275, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789168, Length=466, Percent_Identity=25.9656652360515, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790361, Length=494, Percent_Identity=23.2793522267206, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789138, Length=488, Percent_Identity=24.3852459016393, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=449, Percent_Identity=25.3897550111359, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24655555, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655560, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655570, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655574, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655565, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17864214, Length=461, Percent_Identity=25.3796095444685, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24657106, Length=525, Percent_Identity=22.2857142857143, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24657102, Length=525, Percent_Identity=22.2857142857143, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24654573, Length=393, Percent_Identity=24.6819338422392, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54956; Mature: 54956

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIR
CCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
EVLYRYPETAAQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGW
HHHHHCCCHHHHEEEEEECCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHH
EKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMPKDYINFMLTGAMATDYSEAS
HHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCE
CYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQPAADLTGLPAGIPVVAGT
EEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEECC
SDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCEEEECCCCCCEEEEECC
GDAVRWARLALADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQ
CCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHH
RKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIASGGGARSSLWLEIKASAYNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCC
ILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFEKLISPDPLLRDYYHACCELFD
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TLYRQSAALYDRLDALSVGPD
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIR
CCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
EVLYRYPETAAQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGW
HHHHHCCCHHHHEEEEEECCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHH
EKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMPKDYINFMLTGAMATDYSEAS
HHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCE
CYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQPAADLTGLPAGIPVVAGT
EEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEECC
SDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCEEEECCCCCCEEEEECC
GDAVRWARLALADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQ
CCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHH
RKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIASGGGARSSLWLEIKASAYNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCC
ILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFEKLISPDPLLRDYYHACCELFD
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TLYRQSAALYDRLDALSVGPD
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]