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The map label for this gene is deoC

Identifier: 152970254

GI number: 152970254

Start: 1882812

End: 1883561

Strand: Direct

Name: deoC

Synonym: KPN_01702

Alternate gene names: 152970254

Gene position: 1882812-1883561 (Clockwise)

Preceding gene: 152970239

Following gene: 152970255

Centisome position: 35.42

GC content: 57.47

Gene sequence:

>750_bases
ATGAAAGCAATTAAAAACAAAGGACAGGATAAGACCATGAATGAAACAACCCATCGTTTTGCACGTTTAGTTGATCTGAG
CGCAGTTCAGGCCACCAGTACCGAAGCGGATGTTCGCGCCTGCGCCGAGCTGGCTGCCAGATACAACATTATTTCCGTCC
ACGTACTGCCTTGCTGGACGCGCTTTCTCAGTACGTTGCTGCCGCAGCAGGGTACGGGAGAGGTGATGATTGGCGGTCCG
GTCGGCTTTCCCGGCGGTGGGCATACCACCGATACCAAGGTTCAGGAAGTGCGGCAGCTGATTGCCGACGGCGCTCGGGA
AGTGGATATGGTCGTGAATATCGGCAAAGTGCTCTCCGGCGATTATGACTATGTGCGCGAAGATTTGCGCCGCGTGGTGG
AAGCCGCCGCCCCGGTACCGGCCAAAGTGATCCTTGAAACGCACTATCTTAATGAGGAGCAGATTCGTCGCGTGTGCGAA
ATTGCCGTAGAGGTGGGGATGAAGTGGGTCAAAACCTCTACCGGCTGGGCGCCCACCGGCGCCACGGTGGAAAAAGTCAG
GATCATCGCCGACCAGCTTAAAGGCCGAATCGATATCAAAGGCGCCGGGGGCATTCGCGATCTGGCCACGGTGCGTGCGC
TGTACCAGCTTGGCGTGCGCCGCTTTGGCATGAGCCATGGCGCGGTAACCAAGGTGCTGGCTGAACTGGAGCAGCACCCG
GAACGTTTTCCCGAGCTGAACGCCGATTAA

Upstream 100 bases:

>100_bases
TGCTAATTAAAAACAAATGAAAATAAAAAAATGCTAATTTGATCACGTTATTTTCATTTAATGCGTTTTTAAATGGATTT
AAGCCAAATGTCAGCATTAA

Downstream 100 bases:

>100_bases
ACTGAGAGACCGCGGGCCTGGTGGCCCGCCTTAAGACGTCACCGGAGTTAGTGATGAAAGATAAAATACTCACGATTGAT
GTTGGCACTGGCAGTACCCG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKAIKNKGQDKTMNETTHRFARLVDLSAVQATSTEADVRACAELAARYNIISVHVLPCWTRFLSTLLPQQGTGEVMIGGP
VGFPGGGHTTDTKVQEVRQLIADGAREVDMVVNIGKVLSGDYDYVREDLRRVVEAAAPVPAKVILETHYLNEEQIRRVCE
IAVEVGMKWVKTSTGWAPTGATVEKVRIIADQLKGRIDIKGAGGIRDLATVRALYQLGVRRFGMSHGAVTKVLAELEQHP
ERFPELNAD

Sequences:

>Translated_249_residues
MKAIKNKGQDKTMNETTHRFARLVDLSAVQATSTEADVRACAELAARYNIISVHVLPCWTRFLSTLLPQQGTGEVMIGGP
VGFPGGGHTTDTKVQEVRQLIADGAREVDMVVNIGKVLSGDYDYVREDLRRVVEAAAPVPAKVILETHYLNEEQIRRVCE
IAVEVGMKWVKTSTGWAPTGATVEKVRIIADQLKGRIDIKGAGGIRDLATVRALYQLGVRRFGMSHGAVTKVLAELEQHP
ERFPELNAD
>Mature_249_residues
MKAIKNKGQDKTMNETTHRFARLVDLSAVQATSTEADVRACAELAARYNIISVHVLPCWTRFLSTLLPQQGTGEVMIGGP
VGFPGGGHTTDTKVQEVRQLIADGAREVDMVVNIGKVLSGDYDYVREDLRRVVEAAAPVPAKVILETHYLNEEQIRRVCE
IAVEVGMKWVKTSTGWAPTGATVEKVRIIADQLKGRIDIKGAGGIRDLATVRALYQLGVRRFGMSHGAVTKVLAELEQHP
ERFPELNAD

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=133, Percent_Identity=33.0827067669173, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1790841, Length=223, Percent_Identity=29.5964125560538, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_KLEP7 (A6T962)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001335363.1
- ProteinModelPortal:   A6T962
- SMR:   A6T962
- STRING:   A6T962
- GeneID:   5341899
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_01702
- eggNOG:   COG0274
- HOGENOM:   HBG636421
- OMA:   WRAIETE
- ProtClustDB:   CLSK886450
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 27314; Mature: 27314

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: ACT_SITE 171-171 ACT_SITE 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIKNKGQDKTMNETTHRFARLVDLSAVQATSTEADVRACAELAARYNIISVHVLPCWT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEHHHHHHH
RFLSTLLPQQGTGEVMIGGPVGFPGGGHTTDTKVQEVRQLIADGAREVDMVVNIGKVLSG
HHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
DYDYVREDLRRVVEAAAPVPAKVILETHYLNEEQIRRVCEIAVEVGMKWVKTSTGWAPTG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCC
ATVEKVRIIADQLKGRIDIKGAGGIRDLATVRALYQLGVRRFGMSHGAVTKVLAELEQHP
CHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ERFPELNAD
HHCCCCCCC
>Mature Secondary Structure
MKAIKNKGQDKTMNETTHRFARLVDLSAVQATSTEADVRACAELAARYNIISVHVLPCWT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEHHHHHHH
RFLSTLLPQQGTGEVMIGGPVGFPGGGHTTDTKVQEVRQLIADGAREVDMVVNIGKVLSG
HHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
DYDYVREDLRRVVEAAAPVPAKVILETHYLNEEQIRRVCEIAVEVGMKWVKTSTGWAPTG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCC
ATVEKVRIIADQLKGRIDIKGAGGIRDLATVRALYQLGVRRFGMSHGAVTKVLAELEQHP
CHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ERFPELNAD
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA