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The map label for this gene is amiC [H]

Identifier: 152970168

GI number: 152970168

Start: 1796429

End: 1797646

Strand: Direct

Name: amiC [H]

Synonym: KPN_01616

Alternate gene names: 152970168

Gene position: 1796429-1797646 (Clockwise)

Preceding gene: 152970167

Following gene: 152970169

Centisome position: 33.8

GC content: 59.11

Gene sequence:

>1218_bases
ATGGGTCTCTCCTTTCAGGCCTATGCCGCCGACACCATCAAAGTCGGGATCATGCATTCGCTCTCCGGGACGATGGCGAT
TTCCGAAACGCCGCTGAAAGACGTCGCGCTGATGGCCATCGACGACATCAACGCCAAAGGCGGGGTGCTGGGCAAGAAAC
TGGAGCCGGTGGTGGTCGACCCGGCCTCCAACTGGCCGCTGTTTGCCGAGAAGGCGCGCCAGCTGCTGGCCCAGGATAAA
GTGGCGGTGGTGTTTGGCTGCTGGACGTCGGTCTCGCGTAAATCGGTCCTGCCGGTGTTTGAGGAGCTGAACGGCCTGCT
GTTCTATCCGGTGCAGTACGAAGGGGAAGAGATGTCCCCCAACGTCTTCTATACCGGCGCGGCGCCTAACCAGCAGGCTA
TCCCGGCGGTGGAATACCTGCTGAGCGAGGACGGCGGCGGCGCTAAACGTTTCTTTCTGCTGGGGACGGACTACGTCTAT
CCGCGCACCACCAACAAGATCCTCCGCGCCTTTCTGCATGCCAAAGGGATCCAGGACAAAGATATCGAGGAGGTCTACAC
CCCGTTCGGCTACAGCGATTACCAGACCATCGTCGCCAATATCAAAAAATTCGCCGCCGGTGGCAAAACGGCAGTGGTCT
CCACCATCAATGGCGATTCCAACGTACCGTTCTACAAAGAGCTGGCTAACCAGGGTCTGAAAGCGACCGATGTACCGGTG
GTGGCCTTCTCGGTGGGGGAAGAGGAGCTGCGCGGCATCGATACCAAACCGCTGGTCGGCAACCTCGCGGCATGGAACTA
CTTTGAATCCGTCGATAATCCGACCAACAAAGCCTTCGTCGCCGATTATCGCGCGTATGCCAAAGCGCACAAGCTGCCGA
ATGCCGATACGGTGGTGACCAACGATCCGATGGAAGCGACCTGGGTGGGCCTGCATATGTGGGCGCAGGCGGTGACCAAA
GCGGGCACCACCGATGTTAACAAAGTACGCGAGGCGATGGCCGGGCAGACCTTCAAAGCGCCGTCCGGATTTACCCTGAC
CATGGATGCCACCAACCACCATCTGCATAAGCCGGTGATGATCGGTGAAATTGAAGGCAACGGCCAGTTCAACGTGGTCT
GGCAGACCGATGAGCCCGTCCGCGCGCAGCCGTGGAGCCCGTGGATCCCCGGTAATGATAAGAAACCTGACCATCCGGTG
AAAACCGTCAGCCAGTAA

Upstream 100 bases:

>100_bases
GGTTAGCTGTTAATTCTTTATTTTTTGCGCTACTCAGGAGTGAATCATGCAACGTAGAACGTTATTAAAAGCTTTTGCAC
TCTCCGCCTCTGTTATGGCT

Downstream 100 bases:

>100_bases
GCGCCACGGCCGACGGGGCGGGAGCGTCGCGCCCGTCGGCCGCTGACCAGAGGAGAACGACATGAACGCATTGCGTCTCA
TGAGTGTGTTGGCGCTATTG

Product: high-affinity branched-chain amino acid ABC transporter periplasmic substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MGLSFQAYAADTIKVGIMHSLSGTMAISETPLKDVALMAIDDINAKGGVLGKKLEPVVVDPASNWPLFAEKARQLLAQDK
VAVVFGCWTSVSRKSVLPVFEELNGLLFYPVQYEGEEMSPNVFYTGAAPNQQAIPAVEYLLSEDGGGAKRFFLLGTDYVY
PRTTNKILRAFLHAKGIQDKDIEEVYTPFGYSDYQTIVANIKKFAAGGKTAVVSTINGDSNVPFYKELANQGLKATDVPV
VAFSVGEEELRGIDTKPLVGNLAAWNYFESVDNPTNKAFVADYRAYAKAHKLPNADTVVTNDPMEATWVGLHMWAQAVTK
AGTTDVNKVREAMAGQTFKAPSGFTLTMDATNHHLHKPVMIGEIEGNGQFNVVWQTDEPVRAQPWSPWIPGNDKKPDHPV
KTVSQ

Sequences:

>Translated_405_residues
MGLSFQAYAADTIKVGIMHSLSGTMAISETPLKDVALMAIDDINAKGGVLGKKLEPVVVDPASNWPLFAEKARQLLAQDK
VAVVFGCWTSVSRKSVLPVFEELNGLLFYPVQYEGEEMSPNVFYTGAAPNQQAIPAVEYLLSEDGGGAKRFFLLGTDYVY
PRTTNKILRAFLHAKGIQDKDIEEVYTPFGYSDYQTIVANIKKFAAGGKTAVVSTINGDSNVPFYKELANQGLKATDVPV
VAFSVGEEELRGIDTKPLVGNLAAWNYFESVDNPTNKAFVADYRAYAKAHKLPNADTVVTNDPMEATWVGLHMWAQAVTK
AGTTDVNKVREAMAGQTFKAPSGFTLTMDATNHHLHKPVMIGEIEGNGQFNVVWQTDEPVRAQPWSPWIPGNDKKPDHPV
KTVSQ
>Mature_404_residues
GLSFQAYAADTIKVGIMHSLSGTMAISETPLKDVALMAIDDINAKGGVLGKKLEPVVVDPASNWPLFAEKARQLLAQDKV
AVVFGCWTSVSRKSVLPVFEELNGLLFYPVQYEGEEMSPNVFYTGAAPNQQAIPAVEYLLSEDGGGAKRFFLLGTDYVYP
RTTNKILRAFLHAKGIQDKDIEEVYTPFGYSDYQTIVANIKKFAAGGKTAVVSTINGDSNVPFYKELANQGLKATDVPVV
AFSVGEEELRGIDTKPLVGNLAAWNYFESVDNPTNKAFVADYRAYAKAHKLPNADTVVTNDPMEATWVGLHMWAQAVTKA
GTTDVNKVREAMAGQTFKAPSGFTLTMDATNHHLHKPVMIGEIEGNGQFNVVWQTDEPVRAQPWSPWIPGNDKKPDHPVK
TVSQ

Specific function: Negatively regulates the expression of the aliphatic amidase operon. AmiC functions by inhibiting the action of AmiR at the protein level. It exhibits protein kinase activity [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000709 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44249; Mature: 44117

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSFQAYAADTIKVGIMHSLSGTMAISETPLKDVALMAIDDINAKGGVLGKKLEPVVVD
CCCCCEEECCCEEEEEEEECCCCCEEECCCCCHHEEEEEEECCCCCCCCCCCCCCCEEEC
PASNWPLFAEKARQLLAQDKVAVVFGCWTSVSRKSVLPVFEELNGLLFYPVQYEGEEMSP
CCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCC
NVFYTGAAPNQQAIPAVEYLLSEDGGGAKRFFLLGTDYVYPRTTNKILRAFLHAKGIQDK
CEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCEECCCCHHHHHHHHHHHCCCCCC
DIEEVYTPFGYSDYQTIVANIKKFAAGGKTAVVSTINGDSNVPFYKELANQGLKATDVPV
CHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCE
VAFSVGEEELRGIDTKPLVGNLAAWNYFESVDNPTNKAFVADYRAYAKAHKLPNADTVVT
EEEECCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCEEEE
NDPMEATWVGLHMWAQAVTKAGTTDVNKVREAMAGQTFKAPSGFTLTMDATNHHLHKPVM
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEE
IGEIEGNGQFNVVWQTDEPVRAQPWSPWIPGNDKKPDHPVKTVSQ
EEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLSFQAYAADTIKVGIMHSLSGTMAISETPLKDVALMAIDDINAKGGVLGKKLEPVVVD
CCCCEEECCCEEEEEEEECCCCCEEECCCCCHHEEEEEEECCCCCCCCCCCCCCCEEEC
PASNWPLFAEKARQLLAQDKVAVVFGCWTSVSRKSVLPVFEELNGLLFYPVQYEGEEMSP
CCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCC
NVFYTGAAPNQQAIPAVEYLLSEDGGGAKRFFLLGTDYVYPRTTNKILRAFLHAKGIQDK
CEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCEECCCCHHHHHHHHHHHCCCCCC
DIEEVYTPFGYSDYQTIVANIKKFAAGGKTAVVSTINGDSNVPFYKELANQGLKATDVPV
CHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCE
VAFSVGEEELRGIDTKPLVGNLAAWNYFESVDNPTNKAFVADYRAYAKAHKLPNADTVVT
EEEECCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCEEEE
NDPMEATWVGLHMWAQAVTKAGTTDVNKVREAMAGQTFKAPSGFTLTMDATNHHLHKPVM
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEE
IGEIEGNGQFNVVWQTDEPVRAQPWSPWIPGNDKKPDHPVKTVSQ
EEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1907262; 10984043; 1762155; 7813419; 10508151; 10708652 [H]