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The map label for this gene is umuD [H]

Identifier: 152969991

GI number: 152969991

Start: 1595512

End: 1595931

Strand: Direct

Name: umuD [H]

Synonym: KPN_01438

Alternate gene names: 152969991

Gene position: 1595512-1595931 (Clockwise)

Preceding gene: 152969990

Following gene: 152969992

Centisome position: 30.02

GC content: 51.9

Gene sequence:

>420_bases
ATGCAGTTCTACACTCCCGTTGAGTTACGTCAGATCATGCTGCTCCCGTTGTACAGCGACCTTGTGCAATGTGGTTTTCC
AAGTCCTGCGCAGGACTACGTTGAGCAACGTATCGATCTGAACGAGTTGCTCGTTAACCACCCCAGTGCGACGTATTTTG
TCAAAGCCGCCGGCGACAGCATGAAGGATGCCGGCATAGGGGAAGGTGATCTTCTTGTTGTGGATAGCTCAAGGACAGCA
GTTCATGGCGATATCGTTATCGCTGCAGTGGATGGGGAATTCACCGTTAAGAAGCTGCAGCTGCATCCGCGGGTTCAGCT
TAACCCAATGAACCCTGCATATTCGCCGATAGTCGTGGGTAGCGAGGATACTCTCGATGTGTTCGGGGTCGTAACTTACA
TCATCAAATCGGCTGGCTGA

Upstream 100 bases:

>100_bases
TTACGTCAATGGCGTAAATTGATAGCCAGAGCCTATATTGATATGTCGCCCTGTCAAAACTACTGTATATAAAAACAGTG
TTAATGTGAGCGAGACTATT

Downstream 100 bases:

>100_bases
GATGTTTGCACTTTGCGATGTGAACTCATTTTACGCATCCTGCGAAACTGTTTTCCGTCCTGACCTGAAGGGGCGGCCGG
TGGTCGTTCTGTCAAACAAC

Product: DNA polymerase V subunit UmuD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MQFYTPVELRQIMLLPLYSDLVQCGFPSPAQDYVEQRIDLNELLVNHPSATYFVKAAGDSMKDAGIGEGDLLVVDSSRTA
VHGDIVIAAVDGEFTVKKLQLHPRVQLNPMNPAYSPIVVGSEDTLDVFGVVTYIIKSAG

Sequences:

>Translated_139_residues
MQFYTPVELRQIMLLPLYSDLVQCGFPSPAQDYVEQRIDLNELLVNHPSATYFVKAAGDSMKDAGIGEGDLLVVDSSRTA
VHGDIVIAAVDGEFTVKKLQLHPRVQLNPMNPAYSPIVVGSEDTLDVFGVVTYIIKSAG
>Mature_139_residues
MQFYTPVELRQIMLLPLYSDLVQCGFPSPAQDYVEQRIDLNELLVNHPSATYFVKAAGDSMKDAGIGEGDLLVVDSSRTA
VHGDIVIAAVDGEFTVKKLQLHPRVQLNPMNPAYSPIVVGSEDTLDVFGVVTYIIKSAG

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=137, Percent_Identity=74.4525547445255, Blast_Score=216, Evalue=6e-58,
Organism=Escherichia coli, GI1790476, Length=126, Percent_Identity=34.1269841269841, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15153; Mature: 15153

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFYTPVELRQIMLLPLYSDLVQCGFPSPAQDYVEQRIDLNELLVNHPSATYFVKAAGDS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCCC
MKDAGIGEGDLLVVDSSRTAVHGDIVIAAVDGEFTVKKLQLHPRVQLNPMNPAYSPIVVG
CCCCCCCCCCEEEEECCCCEEECCEEEEEECCCEEEEEEEECCCEEECCCCCCCCEEEEC
SEDTLDVFGVVTYIIKSAG
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQFYTPVELRQIMLLPLYSDLVQCGFPSPAQDYVEQRIDLNELLVNHPSATYFVKAAGDS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCCC
MKDAGIGEGDLLVVDSSRTAVHGDIVIAAVDGEFTVKKLQLHPRVQLNPMNPAYSPIVVG
CCCCCCCCCCEEEEECCCCEEECCEEEEEECCCEEEEEEEECCCEEECCCCCCCCEEEEC
SEDTLDVFGVVTYIIKSAG
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]