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The map label for this gene is licH [H]

Identifier: 152969858

GI number: 152969858

Start: 1463109

End: 1464422

Strand: Direct

Name: licH [H]

Synonym: KPN_01304

Alternate gene names: 152969858

Gene position: 1463109-1464422 (Clockwise)

Preceding gene: 152969856

Following gene: 152969859

Centisome position: 27.53

GC content: 58.9

Gene sequence:

>1314_bases
ATGTCAGGACTCAAAATTGTGGTGATCGGTGGTGGCTCCAGCTACACCCCGGAACTGATTGAAGGTTTGCTCAACCGCTA
TCACGAAATGCCGGTCGCTTCGCTATGGCTGGTGGACATTGAAGAGGGCAAAGAGAAAGTCGAGATTATCGCCGGACTGG
CGCGGCGAATGATCGCCAAAGCCGGGCTGACTATTGAAGTGGTGGCCACCCTTGACCGGGAAAGCGCGCTGCGCGATGCC
GATTTCGTCTGCTCGCAGTTTCGCGCCGGCTGCCTTGACGCCCGGATCAGCGATGAACGTATCTCCCTCAAGTATGGCTT
GATCGGCCAGGAGACCAATGGCCTCGGCGGCTTCGCCAACGCCTGCCGCACCATTCCCATCGCCCTGGAGATCGCTGCCG
ATATGGAGCGACTGTGTCCCGACGCCTGGCTGCTGAACTTTACCAACCCGTCGGGGATGGTGACCGAAGCGATCCTGCGC
CACAGCCGCATCAAAGCCGTCGGCCTGTGTAACGTGCCGGTGATTATGCAAAAAGGGATAACCACTCTGCTGCAATGCGC
TGACGAAAAAGAGGTGGTGATGCAGGTCGCCGGCCTGAACCACTTTATCTTCGTGCGCCAGATCCTGCACAAAGGTAAAG
AATGGCTGCCGGAGGTGATAGCCGAGATCAACGCCGGTCGGGATCCGCTGGTGCCGCGCAACATTTCGCCGTTCCGTTGG
CCGTCGCATCTGCTGCAGGGCTTAGGCATGATCCCCTGCGCCTATCTGCGTTATTACTACATGAAAGACGATCTGCTGCG
CCAGGAGCTGGCGGAGGCGGGCGGCGAAGGAACCCGCGGGGAAGTGGTTAAGCAGCTGGAAAAAATCTTGTTTGACCAGT
ACCGCGACCCGCACCTGGCAGTCAAACCGAAGGCGCTGGAAGGGCGCGGCGGCCAGTACTATTCCGAGGCGGCCTGCGAG
CTGATGAATGCCATCTACAACGACAAGCGGATTATCATGCACGTCAATACGCGTAATAACGGCGCCATCAATGGCCTGCC
GGATGACTGCGCGGTAGAGGTCAGCTCGCTGATTACCGCTTCTGGTCCGCTACCTCTCAATGTGGCGCCGTTCCCGGAAG
ATACCCTGCGTTTGCTGCAGCTGATGAAATCATTTGAACGGCTGACTATCGAGGCCGCGCTCACCGGCAACCGCCACACC
GCATGGCGTGCTCTGATGCTGAATCCGCTGATCGTCAGCGGCGAGAAGCTCGAACTGGCGTTGGATGAGGTGATCGCTGA
GAACCGTCAGTGGCTGCCTGCTTTCCACGCCTGA

Upstream 100 bases:

>100_bases
TATGCATTAATTGAGTTCATGCATAGGCCGATTTAATTCGTTTGTTAGGCCAGTTTTGCCGGTTTTAAATAGTTATATCG
TAACTAAACCGAGGTATACC

Downstream 100 bases:

>100_bases
CCCAAGACTCACCGGCCGCCTGGCCGGTGATTTAACCACTGACCGTCTGACTTTACGCCACAGCGCCCATTTTTCCGCCA
CACTGTCAATAATTGTTGAC

Product: putative alpha-galactosidases/6-phospho-beta-glucosidases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAKAGLTIEVVATLDRESALRDA
DFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILR
HSRIKAVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINAGRDPLVPRNISPFRW
PSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLAVKPKALEGRGGQYYSEAACE
LMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHT
AWRALMLNPLIVSGEKLELALDEVIAENRQWLPAFHA

Sequences:

>Translated_437_residues
MSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAKAGLTIEVVATLDRESALRDA
DFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILR
HSRIKAVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINAGRDPLVPRNISPFRW
PSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLAVKPKALEGRGGQYYSEAACE
LMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHT
AWRALMLNPLIVSGEKLELALDEVIAENRQWLPAFHA
>Mature_436_residues
SGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAKAGLTIEVVATLDRESALRDAD
FVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILRH
SRIKAVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINAGRDPLVPRNISPFRWP
SHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLAVKPKALEGRGGQYYSEAACEL
MNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHTA
WRALMLNPLIVSGEKLELALDEVIAENRQWLPAFHA

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=435, Percent_Identity=44.8275862068966, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1790560, Length=468, Percent_Identity=28.8461538461538, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 48422; Mature: 48291

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAK
CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHH
AGLTIEVVATLDRESALRDADFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFAN
CCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEEEEECCCCCCCCHHHH
ACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILRHSRIKAVGLCNVPVIMQKGI
HHHHCCEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHH
TTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINAGRDPLVPRNISPFRW
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VKPKALEGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITA
ECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
SGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHTAWRALMLNPLIVSGEKLELA
CCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCEEECCCHHHHH
LDEVIAENRQWLPAFHA
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAK
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHH
AGLTIEVVATLDRESALRDADFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFAN
CCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEEEEECCCCCCCCHHHH
ACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILRHSRIKAVGLCNVPVIMQKGI
HHHHCCEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHH
TTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINAGRDPLVPRNISPFRW
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VKPKALEGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITA
ECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
SGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHTAWRALMLNPLIVSGEKLELA
CCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCEEECCCHHHHH
LDEVIAENRQWLPAFHA
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]