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The map label for this gene is sohB [H]

Identifier: 152969822

GI number: 152969822

Start: 1422254

End: 1423336

Strand: Direct

Name: sohB [H]

Synonym: KPN_01268

Alternate gene names: 152969822

Gene position: 1422254-1423336 (Clockwise)

Preceding gene: 152969819

Following gene: 152969824

Centisome position: 26.76

GC content: 58.63

Gene sequence:

>1083_bases
GTGCAGCAACGTCAGTGCTTTACACAAGGTGAAAACGTGGAATTACTTGCTCAGTACGGCTTATTTTTAGCCAAGATCGC
GACGGTTGTCGTCGCCATCGCGGTGATTGCCGCTATTATCGTCAACCTCGCTCAGCGCAAGAAGCAGCGCGGCGAGCTGC
GGGTGACCAATCTTAGCGAGCATTATAAAGAGATGAAGGAATCGCTGGCGGTGGCGCTGCTGGACGGCCCGCAGCAGAAG
CAGTGGCATAAGGCGCAGAAGAAAAAGCAAAAACAAGAGGCGAAGGCGGCCAAAGCGCGGGCGAAGCTGGGCAATGCCGA
GCCGGAAGGCAAGCCGCGCGCCTGGGTGCTGGATTTCAAAGGCAGTATGGATGCTCATGAGGTCAATAGCCTGCGGGAAG
AGATCACCGCGGTACTGGCGGCGGCGAAAGCGCGCGATCAGGTGGTGATTCGCCTGGAAAGCCCCGGCGGGGTGGTGCAC
GGCTACGGTCTGGCCGCCTCTCAGCTGCAGCGTTTGCGCGACAAGCAGATCCCGCTGACGGTGTCGGTCGACAAAGTGGC
GGCCAGCGGCGGCTATATGATGGCCTGCGTGGCGAACAAAATTGTCTCGGCGCCGTTTGCGATCCTCGGATCTATTGGTG
TGGTGGCGCAGATCCCGAACCTGCACCGCTTCCTGAAGAATAAAGATATCGATATCGAACTGCACACTGCCGGGCAGTAC
AAACGAACGCTCACCATGCTGGGCGAAAATACCGAGGAAGGGCGGCGCAAGTTCCGCGAGGATCTCAATGAGACACATCA
TTTGTTCAAGGATTTCGTCCACCGGATGCGTCCGGGACTTGATATTGAGCAGGTGGCCACCGGCGAACACTGGTACGGGG
TGCAGGCGCTGGAAAAAGGTCTGGTGGATGCGGTTGAAACCAGCGATGAGCTGCTGCTGGGGCTGATGGAGAGCCACGAG
GTGATCGGGGTGCGTTATCAACAGCGTAAGAAGATGCTCGACCGCTTTACCGGTAGCGCGTCGGAGAGCGCCGATCGGCT
TCTGCTGCGCTGGTGGCAGCGCGGTCAGAAACCGCTGATGTAA

Upstream 100 bases:

>100_bases
TTAATATCTTGCAACGATTTCAGCCGCGCGAAAAAAAACAGAATCCGCTGCGCAGAGAACACAAAGCACAAAGACTTCTC
GCCAGCGGCTGAGGTACACT

Downstream 100 bases:

>100_bases
ATAACATAACGCGAGGCCTGGGCCTCGCGTTATTGTTTTCACTGGTCTTAATCGACCAGGTGGTACTTGTCCGACAGCTC
GTGAGCAAGATACTTAAACA

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQQRQCFTQGENVELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVALLDGPQQK
QWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVH
GYGLAASQLQRLRDKQIPLTVSVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQY
KRTLTMLGENTEEGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELLLGLMESHE
VIGVRYQQRKKMLDRFTGSASESADRLLLRWWQRGQKPLM

Sequences:

>Translated_360_residues
MQQRQCFTQGENVELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVALLDGPQQK
QWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVH
GYGLAASQLQRLRDKQIPLTVSVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQY
KRTLTMLGENTEEGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELLLGLMESHE
VIGVRYQQRKKMLDRFTGSASESADRLLLRWWQRGQKPLM
>Mature_360_residues
MQQRQCFTQGENVELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVALLDGPQQK
QWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVH
GYGLAASQLQRLRDKQIPLTVSVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQY
KRTLTMLGENTEEGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELLLGLMESHE
VIGVRYQQRKKMLDRFTGSASESADRLLLRWWQRGQKPLM

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=82.5214899713467, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1788064, Length=177, Percent_Identity=28.2485875706215, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 40314; Mature: 40314

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRQCFTQGENVELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSE
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHH
HYKEMKESLAVALLDGPQQKQWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
GSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRLRDKQIPLT
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEE
VSVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQY
EEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCH
KRTLTMLGENTEEGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHH
LVDAVETSDELLLGLMESHEVIGVRYQQRKKMLDRFTGSASESADRLLLRWWQRGQKPLM
HHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQQRQCFTQGENVELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSE
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHH
HYKEMKESLAVALLDGPQQKQWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
GSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRLRDKQIPLT
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEE
VSVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQY
EEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCH
KRTLTMLGENTEEGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHH
LVDAVETSDELLLGLMESHEVIGVRYQQRKKMLDRFTGSASESADRLLLRWWQRGQKPLM
HHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]