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The map label for this gene is argD [H]

Identifier: 152969775

GI number: 152969775

Start: 1372183

End: 1373403

Strand: Direct

Name: argD [H]

Synonym: KPN_01221

Alternate gene names: 152969775

Gene position: 1372183-1373403 (Clockwise)

Preceding gene: 152969766

Following gene: 152969776

Centisome position: 25.82

GC content: 62.82

Gene sequence:

>1221_bases
ATGTCTCAGTCAATTACGCGTAACCACTTTGATGAATGGATGATGCCGGTCTACGCGCCAGCGGCGTTTATTCCGGTGCG
GGGCGCCGGGTCACGGCTGTGGGATCAGGAGGGCAAAGAGTATATTGATTTTGCCGGCGGCATCGCCGTGAACGCGCTGG
GGCATGCCCATCCGCGTCTGGTGCAAGCCCTGACCGACCAGGCCGGCAAGTTCTGGCATACCGGCAACGGCTACACCAAT
GAGCCGATCCTGCGTCTGGCCAAAATGCTTATCGATGCTACCTTCGCCGACCGGGTCTTCTTCTGTAACTCCGGCGCCGA
GGCCAATGAGGCAGCGCTCAAGCTGGCGCGTAAATATGCCCACGATCGCTTTGGCAGCGAGAAAAGTGGCATCGTCGCCT
TTCAGAACGCTTTCCACGGGCGGACGCTGTTCACCGTCTCGGCGGGCGGTCAGCCGGCCTATTCCCGGGATTTCGCCCCG
CTGCCGCCGCAGATCCAGCATGCCGTATTTAACGATCTCGAGTCGGCAAAGGCCTTAATCAATGACCAGACCTGCGCAGT
GATCGTCGAGCCGGTGCAGGGCGAAGGGGGCGTGGTGCCGGCCAGCGTCGAGTTTTTACGCGGCCTGCGTCAGCTTTGCG
ACCAGCACAACGCCCTGCTGATTTTCGATGAAGTGCAGACCGGGGTCGGGCGTACCGGCGAGCTGTATGCCTATATGCAC
TACGGCGTGACGCCCGATGTGCTGACCACCGCCAAAGCGCTGGGCGGTGGTTTCCCTATCGGCGCGCTGCTGGCGACAGA
GGCCTGCGCCAGCGTGATGACCGTCGGCACCCACGGCACCACCTACGGCGGTAACCCGCTGGCCGGGGCGGTGGCCGGCG
AACTGCTGTCGATCGTCAACACCCCGGAAGTGCTCTCCGGCGTCAGACAGCGCCATCAGTGGTTTTGTGAACGCCTGCAG
GCAATTAACGCCCGCTATGGCCTGTTCAAGGAGATCCGCGGCCTGGGACTGCTGCTCGGCTGCGTGCTAAACGACGCCTG
GGCCGGGAAGGCGAAAACCCTCAGTAACCTGGCGGCGGAAGAGGGGGTGATGATTCTGATCGCCGGCGCCAACGTGGTGC
GTTTCGCGCCGGCGCTGAACGTCAGTGAAGAAGAGGTGAACAGCGGGCTGGATCGCGTCGAGCGGGCCTGCGCGCGTTTC
GTGGCAGGAGTCTCATCATGA

Upstream 100 bases:

>100_bases
TTATCGCTGGCTGGCACGAACTGTGCAATCTACATTTACAGCGTAATAACTCATATTTATTAACATTATTGCTACTTTTA
ATTTACCGGAAGAGGTCGAT

Downstream 100 bases:

>100_bases
TGGTTATTCGACCGGTGGAGCCGGGCGATTTGCCCGGGCTGCTGAAGCTGGCAGCGGAGACCGGCGGCGGGCTGACCTCG
CTGCCGGTGGATGAAGCGAC

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQEGKEYIDFAGGIAVNALGHAHPRLVQALTDQAGKFWHTGNGYTN
EPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYAHDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAP
LPPQIQHAVFNDLESAKALINDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVNTPEVLSGVRQRHQWFCERLQ
AINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAEEGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARF
VAGVSS

Sequences:

>Translated_406_residues
MSQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQEGKEYIDFAGGIAVNALGHAHPRLVQALTDQAGKFWHTGNGYTN
EPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYAHDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAP
LPPQIQHAVFNDLESAKALINDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVNTPEVLSGVRQRHQWFCERLQ
AINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAEEGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARF
VAGVSS
>Mature_405_residues
SQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQEGKEYIDFAGGIAVNALGHAHPRLVQALTDQAGKFWHTGNGYTNE
PILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYAHDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAPL
PPQIQHAVFNDLESAKALINDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMHY
GVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVNTPEVLSGVRQRHQWFCERLQA
INARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAEEGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARFV
AGVSS

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=31.7829457364341, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=32.4503311258278, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI13994255, Length=410, Percent_Identity=25.8536585365854, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=25.6723716381418, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=25.6544502617801, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI226442705, Length=409, Percent_Identity=24.9388753056235, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI24119277, Length=395, Percent_Identity=25.0632911392405, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI188536080, Length=410, Percent_Identity=24.6341463414634, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI38679950, Length=410, Percent_Identity=24.6341463414634, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI38679946, Length=410, Percent_Identity=24.6341463414634, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=80.2955665024631, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1789759, Length=398, Percent_Identity=59.7989949748744, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=33.5012594458438, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI145693181, Length=388, Percent_Identity=36.0824742268041, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=33.587786259542, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1786349, Length=401, Percent_Identity=30.4239401496259, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786991, Length=296, Percent_Identity=31.7567567567568, Blast_Score=118, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=390, Percent_Identity=33.0769230769231, Blast_Score=220, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=28.0459770114943, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=288, Percent_Identity=32.6388888888889, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=27.7777777777778, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=31.0975609756098, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=23.3100233100233, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=41.3265306122449, Blast_Score=291, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6323470, Length=400, Percent_Identity=34, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=341, Percent_Identity=29.3255131964809, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=23.7762237762238, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=32.7272727272727, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI161085790, Length=448, Percent_Identity=28.7946428571429, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI28574759, Length=443, Percent_Identity=28.2167042889391, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI21356575, Length=354, Percent_Identity=27.4011299435028, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43492; Mature: 43361

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQEGKEYIDFAGGIAVNALGHAHPRL
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCHHHHHHCCCHHHHHHCCCHHHH
VQALTDQAGKFWHTGNGYTNEPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYA
HHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHH
HDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAPLPPQIQHAVFNDLESAKALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEEE
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHC
TPEVLSGVRQRHQWFCERLQAINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
EGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARFVAGVSS
CCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQEGKEYIDFAGGIAVNALGHAHPRL
CCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCHHHHHHCCCHHHHHHCCCHHHH
VQALTDQAGKFWHTGNGYTNEPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYA
HHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHH
HDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAPLPPQIQHAVFNDLESAKALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEEE
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHC
TPEVLSGVRQRHQWFCERLQAINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
EGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARFVAGVSS
CCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA