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The map label for this gene is lpxP [H]

Identifier: 152969721

GI number: 152969721

Start: 1319923

End: 1320837

Strand: Direct

Name: lpxP [H]

Synonym: KPN_01167

Alternate gene names: 152969721

Gene position: 1319923-1320837 (Clockwise)

Preceding gene: 152969719

Following gene: 152969722

Centisome position: 24.83

GC content: 57.27

Gene sequence:

>915_bases
ATGGCCTGCGTATTTAATAAACAACTTTTACACCCGCGTAACTGGCTGACCTGGTTCGGGCTCGGCATCCTCTGGTTAAT
CGTGCAACTGCCTTATCCGCTGCTGCATTTTATCGGCACCAGCGCTGGTCGCCTTTCCCGTCGCTTTCTTAAACGCCGCG
AACATATCGCCCGGCGTAATATCGAACTCTGCTTCCCGGACATGTCGCCAGCGGCGCGCGAGACGCTGATCGATCAAAAC
TTTATGTCGCTGGGAATGGGGCTTATCGAAACCGGCATGGCCTGGTTCTGGAGCGACGAGCGGGTCAAAAAATGGTTTGA
TGTCGAGGGGTTCGCCAACCTTAATCACGCGCTTAGCGGTGGGAAAGGGGTAATGGTCGTCGGCGTGCACTTTATGTCGC
TGGAGCTGGGCGGCCGCGCGATGGGGCTGTGTCGGCCAATGATGGCCACCTACCGGCCGCACAACAGCCCGCTGATGGAG
TGGGTGCAAACCCGCGGTCGCCTGCGTTCGAACAAAGCGATGATCGATCGCAACAATCTGACCGGTCTGGTGCATGCCTT
GAAATCCGGTGAAGCGGTGTGGTTCGCGCCCGATCAGGATTACGGTCCCAAGGGCAGCGTCTTTGCACCTTTTTTCTCCG
TCCCGCAGGCGGCGACCACCAACGGCACCTATGTCCTGTCCCGCTTATCGGGCGCGAAAATGTTGAGCATCAGCATGGTA
CGTAAGCTGGATCGCCGGGGCTATAGCCTGCATATCAGCGAGGTGATGAATGACTATCCGGGTGAGGATAAGCAGATCGC
CGCCGGCTATATCAACAAGGTTATTGAGCGCGAGATCCTGCGCGCTCCCGAGCAGTATCTGTGGGTACACCGTCGTTTTA
AAACCCGCCCGCTGGGCGAACCTTCCGTCTATTAA

Upstream 100 bases:

>100_bases
ATTAGTATTGTCGAACTTGCTGTACGTACCGCCTAATGATGATAAATGGATTCTGTTTTCCTTAAGCGTTACCACATAAT
TAATGTTTACAGGAAAAATC

Downstream 100 bases:

>100_bases
CCTTCCCGCACAGGCTGCGCTTTCAAAATCCCGACAGTTGGGGTAACGTGAGCCGGATCATGTTTTAGTCGTGCGCGAAG
GAGTGCAGAGTGTTCGCTGA

Product: putative lipid A biosynthesis acyltransferase

Products: KDO2-(palmitoleoyl)-lipid IVA [C]

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MACVFNKQLLHPRNWLTWFGLGILWLIVQLPYPLLHFIGTSAGRLSRRFLKRREHIARRNIELCFPDMSPAARETLIDQN
FMSLGMGLIETGMAWFWSDERVKKWFDVEGFANLNHALSGGKGVMVVGVHFMSLELGGRAMGLCRPMMATYRPHNSPLME
WVQTRGRLRSNKAMIDRNNLTGLVHALKSGEAVWFAPDQDYGPKGSVFAPFFSVPQAATTNGTYVLSRLSGAKMLSISMV
RKLDRRGYSLHISEVMNDYPGEDKQIAAGYINKVIEREILRAPEQYLWVHRRFKTRPLGEPSVY

Sequences:

>Translated_304_residues
MACVFNKQLLHPRNWLTWFGLGILWLIVQLPYPLLHFIGTSAGRLSRRFLKRREHIARRNIELCFPDMSPAARETLIDQN
FMSLGMGLIETGMAWFWSDERVKKWFDVEGFANLNHALSGGKGVMVVGVHFMSLELGGRAMGLCRPMMATYRPHNSPLME
WVQTRGRLRSNKAMIDRNNLTGLVHALKSGEAVWFAPDQDYGPKGSVFAPFFSVPQAATTNGTYVLSRLSGAKMLSISMV
RKLDRRGYSLHISEVMNDYPGEDKQIAAGYINKVIEREILRAPEQYLWVHRRFKTRPLGEPSVY
>Mature_303_residues
ACVFNKQLLHPRNWLTWFGLGILWLIVQLPYPLLHFIGTSAGRLSRRFLKRREHIARRNIELCFPDMSPAARETLIDQNF
MSLGMGLIETGMAWFWSDERVKKWFDVEGFANLNHALSGGKGVMVVGVHFMSLELGGRAMGLCRPMMATYRPHNSPLMEW
VQTRGRLRSNKAMIDRNNLTGLVHALKSGEAVWFAPDQDYGPKGSVFAPFFSVPQAATTNGTYVLSRLSGAKMLSISMVR
KLDRRGYSLHISEVMNDYPGEDKQIAAGYINKVIEREILRAPEQYLWVHRRFKTRPLGEPSVY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=302, Percent_Identity=70.8609271523179, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1787292, Length=300, Percent_Identity=52, Blast_Score=351, Evalue=4e-98,
Organism=Escherichia coli, GI1788161, Length=306, Percent_Identity=24.8366013071895, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 34704; Mature: 34573

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACVFNKQLLHPRNWLTWFGLGILWLIVQLPYPLLHFIGTSAGRLSRRFLKRREHIARRN
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
IELCFPDMSPAARETLIDQNFMSLGMGLIETGMAWFWSDERVKKWFDVEGFANLNHALSG
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHEECHHHHHHHHCCCCHHCHHHHHCC
GKGVMVVGVHFMSLELGGRAMGLCRPMMATYRPHNSPLMEWVQTRGRLRSNKAMIDRNNL
CCEEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCH
TGLVHALKSGEAVWFAPDQDYGPKGSVFAPFFSVPQAATTNGTYVLSRLSGAKMLSISMV
HHHHHHHHCCCEEEECCCCCCCCCCCEECHHHCCCCCCCCCCCEEEEHHCCCHHHHHHHH
RKLDRRGYSLHISEVMNDYPGEDKQIAAGYINKVIEREILRAPEQYLWVHRRFKTRPLGE
HHHHHCCCEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
PSVY
CCCC
>Mature Secondary Structure 
ACVFNKQLLHPRNWLTWFGLGILWLIVQLPYPLLHFIGTSAGRLSRRFLKRREHIARRN
CCCCCCHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
IELCFPDMSPAARETLIDQNFMSLGMGLIETGMAWFWSDERVKKWFDVEGFANLNHALSG
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHEECHHHHHHHHCCCCHHCHHHHHCC
GKGVMVVGVHFMSLELGGRAMGLCRPMMATYRPHNSPLMEWVQTRGRLRSNKAMIDRNNL
CCEEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCH
TGLVHALKSGEAVWFAPDQDYGPKGSVFAPFFSVPQAATTNGTYVLSRLSGAKMLSISMV
HHHHHHHHCCCEEEECCCCCCCCCCCEECHHHCCCCCCCCCCCEEEEHHCCCHHHHHHHH
RKLDRRGYSLHISEVMNDYPGEDKQIAAGYINKVIEREILRAPEQYLWVHRRFKTRPLGE
HHHHHCCCEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
PSVY
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; palmitoleoyl-ACP [C]

Specific reaction: KDO2-lipid IVA + palmitoleoyl-ACP = KDO2-(palmitoleoyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]