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The map label for this gene is yeaS

Identifier: 152969722

GI number: 152969722

Start: 1320927

End: 1321565

Strand: Direct

Name: yeaS

Synonym: KPN_01168

Alternate gene names: 152969722

Gene position: 1320927-1321565 (Clockwise)

Preceding gene: 152969721

Following gene: 152969723

Centisome position: 24.85

GC content: 56.49

Gene sequence:

>639_bases
GTGTTCGCTGAGTTTGGTGTTCTGAATTATTTAACCTATCTGGTCGGGGCGGTGTTTATCATCCTCGTTCCTGGCCCTAA
TACGTTTTTCGTGCTGAAAACGGGTATTGCCCACGGGGTGAAGAAAGGCTATCTGGCGGCGGCGGGCGTCTTTATTGGCG
ACGCAGTGCTGATGTTTCTGGCCTTCGCCGGGGTGGCGACGCTGATTAAAACCACGCCGGTGTTGTTTAACGTCGTGCGC
TACCTCGGGGCAATTTACCTGCTGTGGCTCGGGGGCAAAATGCTCTATGCGGTGCTGACCCAGCGCGACGGCCAGTCCGA
CGCCAGCGCGGAGCCGGCGAGCGCGATCCTCAAGCGCTCCCTGACCCTGAGCCTGACCAATCCGAAAGCGATTCTGTTCT
ATGTGTCGTTTTTCGTGCAGTTTATCGATGTCAACGCCAAAACTCCCGGCGTGGCGTTCTTTATCCTGGCGCTGACCCTC
GAGGTGATTAGCTTCTGCTATATGAGCTTTTTGATCCTCTCCGGCTCGTTTGTCACCCGCTACGTCAAAACCCGCAAGAA
GCTGGCTAAACTTGGCAACAGCCTGATTGGTCTGGTTTTCGTCGGGTTCGCCGCGCGCCTGGCTACCCTGCAGTCCTGA

Upstream 100 bases:

>100_bases
CCGTCTATTAACCTTCCCGCACAGGCTGCGCTTTCAAAATCCCGACAGTTGGGGTAACGTGAGCCGGATCATGTTTTAGT
CGTGCGCGAAGGAGTGCAGA

Downstream 100 bases:

>100_bases
TCCCCACGGGCCGGTTACCCGCTGACCGGCCCGCCGTCTCTTATTCTGCCCTGTAACAAAAACCCTTCATTTTTTATTGC
ATTGGTGTTACATATACAGC

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFAEFGVLNYLTYLVGAVFIILVPGPNTFFVLKTGIAHGVKKGYLAAAGVFIGDAVLMFLAFAGVATLIKTTPVLFNVVR
YLGAIYLLWLGGKMLYAVLTQRDGQSDASAEPASAILKRSLTLSLTNPKAILFYVSFFVQFIDVNAKTPGVAFFILALTL
EVISFCYMSFLILSGSFVTRYVKTRKKLAKLGNSLIGLVFVGFAARLATLQS

Sequences:

>Translated_212_residues
MFAEFGVLNYLTYLVGAVFIILVPGPNTFFVLKTGIAHGVKKGYLAAAGVFIGDAVLMFLAFAGVATLIKTTPVLFNVVR
YLGAIYLLWLGGKMLYAVLTQRDGQSDASAEPASAILKRSLTLSLTNPKAILFYVSFFVQFIDVNAKTPGVAFFILALTL
EVISFCYMSFLILSGSFVTRYVKTRKKLAKLGNSLIGLVFVGFAARLATLQS
>Mature_212_residues
MFAEFGVLNYLTYLVGAVFIILVPGPNTFFVLKTGIAHGVKKGYLAAAGVFIGDAVLMFLAFAGVATLIKTTPVLFNVVR
YLGAIYLLWLGGKMLYAVLTQRDGQSDASAEPASAILKRSLTLSLTNPKAILFYVSFFVQFIDVNAKTPGVAFFILALTL
EVISFCYMSFLILSGSFVTRYVKTRKKLAKLGNSLIGLVFVGFAARLATLQS

Specific function: Exporter of leucine

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family

Homologues:

Organism=Escherichia coli, GI1788099, Length=212, Percent_Identity=73.5849056603774, Blast_Score=318, Evalue=2e-88,
Organism=Escherichia coli, GI1786522, Length=205, Percent_Identity=30.7317073170732, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI48994979, Length=200, Percent_Identity=27.5, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48994978, Length=203, Percent_Identity=26.1083743842365, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LEUE_KLEP7 (A6T7N0)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001334831.1
- STRING:   A6T7N0
- GeneID:   5339112
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_01168
- eggNOG:   COG1280
- HOGENOM:   HBG759042
- OMA:   RYLGAIY
- ProtClustDB:   PRK10958
- InterPro:   IPR001123

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 22951; Mature: 22951

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14481394)-; HASH(0x14c22700)-; HASH(0x151c2d3c)-; HASH(0x14f11d80)-; HASH(0x14fe2ed4)-; HASH(0x14f8150c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAEFGVLNYLTYLVGAVFIILVPGPNTFFVLKTGIAHGVKKGYLAAAGVFIGDAVLMFL
CCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAGVATLIKTTPVLFNVVRYLGAIYLLWLGGKMLYAVLTQRDGQSDASAEPASAILKRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LTLSLTNPKAILFYVSFFVQFIDVNAKTPGVAFFILALTLEVISFCYMSFLILSGSFVTR
HHEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVKTRKKLAKLGNSLIGLVFVGFAARLATLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFAEFGVLNYLTYLVGAVFIILVPGPNTFFVLKTGIAHGVKKGYLAAAGVFIGDAVLMFL
CCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAGVATLIKTTPVLFNVVRYLGAIYLLWLGGKMLYAVLTQRDGQSDASAEPASAILKRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LTLSLTNPKAILFYVSFFVQFIDVNAKTPGVAFFILALTLEVISFCYMSFLILSGSFVTR
HHEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVKTRKKLAKLGNSLIGLVFVGFAARLATLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA