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The map label for this gene is pgm [H]

Identifier: 152969275

GI number: 152969275

Start: 796083

End: 797723

Strand: Direct

Name: pgm [H]

Synonym: KPN_00711

Alternate gene names: 152969275

Gene position: 796083-797723 (Clockwise)

Preceding gene: 152969274

Following gene: 152969276

Centisome position: 14.98

GC content: 60.21

Gene sequence:

>1641_bases
ATGGCAATCGATAAACGTGCGGGGCAGCCTGCGCAACAGAGTGATTTGATTAACGTCGCCCAACTGACTGCTCAGTACTA
CGTGCTGAAGCCTGAAGTCGGTAATGCGGAGCATGCGGTAAAATTCGGCACCTCTGGCCATCGCGGCAGCGCGGCGCGCC
ACAACTTCAACGAACCGCATATCCTGGCCATCGCCCAGGCCATTGCGGAAGATCGTGCGAAAAACGGGATCACCGGTCCG
TGCTATGTCGGCAAAGATACCCACGCCCTCTCCGAGCCGGCGTTTATTTCGGTGCTGGAAGTGTTAACCGCCAACGGCGT
CGACGTGATCGTGCAGGAAAACAACGGCTTCACCCCGACGCCGGCGGTCTCCAACGCGATTCTGGTGCATAACAAAAAAG
GCGGTCCGCTGGCGGACGGCATTGTGATCACCCCGTCACACAACCCGCCGGAAGATGGTGGTATCAAGTACAATCCGCCA
AACGGCGGCCCGGCTGATACCAACGTCACCAAAGTGGTGGAAAACCGCGCCAACGAACTGCTGGCCGCGGGCCTGCAGGG
CGTGAAACGCATTTCTCTGGACGCGGCGCTGGCTTCTGGCCACGTTAAAGAACAGGATCTGGTGCAGCCGTTCATCGAAG
GGCTGGCGGATATCGTCGATATGGCCGCAATCCAGAAAGCCGGCCTGACGCTGGGCGTCGATCCGCTGGGCGGGTCCGGT
ATCGAATACTGGAAACGCATTGGCGAGCACTACAAGCTCAATCTGACCATTGTTAACGATCAGGTGGATCAGACCTTCCG
CTTTATGCACCTCGATAAAGACGGCGCCATCCGCATGGATTGCTCCTCAGAGTGTGCGATGGCCGGCCTGCTGGCGCTGC
GCGATAAGTTCGATCTGGCGTTTGCTAACGACCCGGATTACGACCGCCACGGGATTGTCACCCCGGCGGGGTTGATGAAC
CCGAACCACTACCTGGCGGTAGCGATCAACTACCTGTTCCAGCATCGTCCGCAGTGGGGCAAAGAGGTGGCGGTGGGTAA
AACGCTGGTCTCCTCCGCGATGATTGACCGCGTGGTGAACGATCTGGGCCGCAAGCTGGTGGAAGTGCCGGTGGGCTTTA
AGTGGTTTGTCGACGGCCTGTTCGATGGCAGCTTCGGCTTCGGCGGCGAAGAGAGCGCCGGGGCCTCCTTCCTGCGCTTC
GACGGCACGCCGTGGTCCACCGATAAAGACGGCATCATCATGTGCCTGCTGGCGGCGGAAATCACCGCGGTGACCGGGAA
AAACCCGCAGGAGCATTACAACGAACTGGCGGAACGCTTCGGTGCGCCGAGCTACAACCGTCTGCAGGCTTCCGCGACCT
CCGCGCAGAAAGCGGCGCTGTCCAAGCTCTCTCCGGAAATGGTCAGCGCTGACACCCTGGCGGGGGATCCGATCACTGCC
CGTCTGACCGCGGCGCCGGGCAACGGGGCGGCGATTGGCGGCCTCAAGGTGATGACCGACAACGGCTGGTTCGCGGCGCG
TCCGTCAGGCACCGAAGACGCCTACAAGATCTACTGCGAAAGCTTCCTCGGCGAAGAGCATCGCAAGCTGATTGAAAAAG
AAGCGGTAGAGATTGTCAGCGAAGTGCTGAAGAACGCTTAA

Upstream 100 bases:

>100_bases
TTGAGCACATCATGCAGTCGATGCAGTTCCCTGCGGAGCTGATTGAAAAGGTTTGCGGCACGATCTAGCTTTTTAACATT
TGCACCAGAAGGATCAGGCA

Downstream 100 bases:

>100_bases
CGACGCACTACCATCAGGCCCCTTGCGGGCCTGATTTTTTTCGCAAGGATAGCGATGAAAATACAACGGAAGTCCCTGTT
TTTGTTCTGGGCGTGGATGG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPHILAIAQAIAEDRAKNGITGP
CYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
NGGPADTNVTKVVENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGVDPLGGSG
IEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMN
PNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRF
DGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTLAGDPITA
RLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVSEVLKNA

Sequences:

>Translated_546_residues
MAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPHILAIAQAIAEDRAKNGITGP
CYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
NGGPADTNVTKVVENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGVDPLGGSG
IEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMN
PNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRF
DGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTLAGDPITA
RLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVSEVLKNA
>Mature_545_residues
AIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPHILAIAQAIAEDRAKNGITGPC
YVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPN
GGPADTNVTKVVENRANELLAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGVDPLGGSGI
EYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNP
NHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFD
GTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTLAGDPITAR
LTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVSEVLKNA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=449, Percent_Identity=25.8351893095768, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI133922562, Length=416, Percent_Identity=24.5192307692308, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI21361621, Length=445, Percent_Identity=25.8426966292135, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=96.1538461538462, Blast_Score=1067, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=537, Percent_Identity=26.0707635009311, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323752, Length=559, Percent_Identity=25.7602862254025, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322722, Length=538, Percent_Identity=27.5092936802974, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17864244, Length=455, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58392; Mature: 58260

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPH
CCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCCCCHHCCCCCCCH
ILAIAQAIAEDRAKNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPT
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCC
PAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVVENRANEL
CCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
LAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGVDPLGGSG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCH
IEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLA
HHHHHHCCCCEEEEEEEECCCHHHHEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCEE
FANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVN
ECCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGIIMCLLAAE
HHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHH
ITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTLAGDPITA
HHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEE
RLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVS
EEEECCCCCCEECCEEEEECCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
EVLKNA
HHHHCC
>Mature Secondary Structure 
AIDKRAGQPAQQSDLINVAQLTAQYYVLKPEVGNAEHAVKFGTSGHRGSAARHNFNEPH
CCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCCCCHHCCCCCCCH
ILAIAQAIAEDRAKNGITGPCYVGKDTHALSEPAFISVLEVLTANGVDVIVQENNGFTPT
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCC
PAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVVENRANEL
CCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
LAAGLQGVKRISLDAALASGHVKEQDLVQPFIEGLADIVDMAAIQKAGLTLGVDPLGGSG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCH
IEYWKRIGEHYKLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLA
HHHHHHCCCCEEEEEEEECCCHHHHEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCEE
FANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPQWGKEVAVGKTLVSSAMIDRVVN
ECCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGIIMCLLAAE
HHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHH
ITAVTGKNPQEHYNELAERFGAPSYNRLQASATSAQKAALSKLSPEMVSADTLAGDPITA
HHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEE
RLTAAPGNGAAIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKLIEKEAVEIVS
EEEECCCCCCEECCEEEEECCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
EVLKNA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]