| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
Click here to switch to the map view.
The map label for this gene is entA [H]
Identifier: 152969185
GI number: 152969185
Start: 696139
End: 696894
Strand: Direct
Name: entA [H]
Synonym: KPN_00614
Alternate gene names: 152969185
Gene position: 696139-696894 (Clockwise)
Preceding gene: 152969184
Following gene: 152969186
Centisome position: 13.1
GC content: 64.42
Gene sequence:
>756_bases ATGGCGGCGCTGGATTTCCACGGTCAGACCGTGTGGGTGACCGGCGCAGGTAAAGGGATTGGCTATGCCACCGCGCTGGC TTTCGTCGAGGCCGGGGCCAACGTTACCGGTTTCGACCTTGCCTTTGACGGCGAAGGTTATCCGTTTGCCACCGAAACGC TGGACGTCGCCGATGCCGGTCAGGTACGCGACGTGTGCGCGCGGCTGCTCAACAACATCGAACGACTGGACGTGCTGGTG AACGCCGCCGGGATCCTGCGCATGGGCGCCACCGACCAGCTGAGCGCGGAAGACTGGCAGCAAACCTTCGCGGTCAACGT TGGCGGCGCGTTTAATCTGTTTCAGCAGACGATGGCCCAGTTCCGCCGTCAGCGGGGCGGGGCGATCGTCACCGTCGCCT CCGATGCCGCGCATACGCCGCGTATCGGCATGAGCGCCTATGGCGCCTCGAAAGCGGCGCTGAAAAGCCTGGCGTTAACC GTTGGCCTTGAGCTGGCAGGCAGCGGCGTGCGCTGCAACCTCGTGTCGCCGGGCTCCACCGACACCGATATGCAGCGCAC CCTGTGGGTCAGCGACGATGCCGAGCAGCAGCGGATCCGCGGCTTCGGCGAGCAGTTTAAGCTCGGCATCCCGCTGGGCA AAATCGCCCGCCCGCAGGAGATCGCCAATACCATTCTGTTCCTCGCCTCTTCTCACGCCAGCCATATTACGCTGCAGGAT ATTGTGGTCGATGGCGGCTCGACGCTGGGGGCGTAA
Upstream 100 bases:
>100_bases CCCGCTGGCGCAAAGTGCACGGCGATATCGACTTCGTGATGCTGGCGAAGAACCCGACCATCGACGCCTGGTGGGCGCTG CTCTCCCGTGAGGTGAAATA
Downstream 100 bases:
>100_bases ATGGCCTGGAAGCGAGAGCTCACGCTGGCGGCGCTGAACGCCAGCAGCGAAAACACCATGGTGGCGCATCTTGGCATCAT CTACACCCGACTGGAAGCGG
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGEGYPFATETLDVADAGQVRDVCARLLNNIERLDVLV NAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALT VGLELAGSGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASSHASHITLQD IVVDGGSTLGA
Sequences:
>Translated_251_residues MAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGEGYPFATETLDVADAGQVRDVCARLLNNIERLDVLV NAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALT VGLELAGSGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASSHASHITLQD IVVDGGSTLGA >Mature_250_residues AALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGEGYPFATETLDVADAGQVRDVCARLLNNIERLDVLVN AAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTV GLELAGSGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASSHASHITLQDI VVDGGSTLGA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=30.46875, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.0813008130081, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=31.25, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI4504505, Length=210, Percent_Identity=32.3809523809524, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=24.3346007604563, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=31.0756972111554, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=32.2751322751323, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=26.5625, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=27.7056277056277, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=23.5294117647059, Blast_Score=68, Evalue=6e-12, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=89.5161290322581, Blast_Score=447, Evalue=1e-127, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=32.8, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=30.078125, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=29.9610894941634, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.1338582677165, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=25.3012048192771, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=30.952380952381, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=28.7449392712551, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=26.6409266409266, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=28.9772727272727, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=33.8345864661654, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=32.4110671936759, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=33.5849056603774, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=33.587786259542, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=33.206106870229, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=30.9160305343511, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=29.2490118577075, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.8352059925094, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=26.8382352941176, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=31.2267657992565, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=32.5842696629214, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=31.9548872180451, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.188679245283, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508651, Length=195, Percent_Identity=30.2564102564103, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=29.3877551020408, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=27.6119402985075, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=28.3400809716599, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=27.3076923076923, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=28.4584980237154, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=28.996282527881, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.7566539923954, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=28.8617886178862, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=28.4671532846715, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=232, Percent_Identity=29.7413793103448, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17568967, Length=206, Percent_Identity=29.126213592233, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.0606060606061, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=28.1853281853282, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=27.4074074074074, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI212645366, Length=245, Percent_Identity=31.0204081632653, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=28.2722513089005, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193207185, Length=148, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193210355, Length=219, Percent_Identity=27.3972602739726, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=26.2357414448669, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=266, Percent_Identity=28.1954887218045, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=22.9571984435798, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.6, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.1428571428571, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=31.0756972111554, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=31.496062992126, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=31.640625, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.0395256916996, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=31.5384615384615, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=33.6842105263158, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=30.6382978723404, Blast_Score=69, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 26361; Mature: 26230
Theoretical pI: Translated: 4.84; Mature: 4.84
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGEGYPFATETLDVADAG CCEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEECCEECCCCCC QVRDVCARLLNNIERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQ HHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHHHHEEEEECCCHHHHHHHHHHH FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGSGVRCNLVSPGST HHHHCCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEECCCCEEEEEECCCCC DTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASSHASHITLQD CCCCEEEEEECCCHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE IVVDGGSTLGA EEEECCCCCCC >Mature Secondary Structure AALDFHGQTVWVTGAGKGIGYATALAFVEAGANVTGFDLAFDGEGYPFATETLDVADAG CEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEECCEECCCCCC QVRDVCARLLNNIERLDVLVNAAGILRMGATDQLSAEDWQQTFAVNVGGAFNLFQQTMAQ HHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHHHHEEEEECCCHHHHHHHHHHH FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGSGVRCNLVSPGST HHHHCCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEECCCCEEEEEECCCCC DTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASSHASHITLQD CCCCEEEEEECCCHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE IVVDGGSTLGA EEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]