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The map label for this gene is ytbD [H]

Identifier: 152968798

GI number: 152968798

Start: 256751

End: 257941

Strand: Direct

Name: ytbD [H]

Synonym: KPN_00223

Alternate gene names: 152968798

Gene position: 256751-257941 (Clockwise)

Preceding gene: 152968796

Following gene: 152968799

Centisome position: 4.83

GC content: 60.2

Gene sequence:

>1191_bases
ATGCCACTGGCGCTATTTGCCTTAACCATCGGTGCCTTCGCAATTGGCACCACTGAATTTGTGATTGTCGGCCTGGTCCC
GACCATTGCTCAGCAACTCTCTATCTCCCTGCCTTCGGCGGGACTGCTGGTCTCTATCTACGCGCTGGGCGTGGCGATCG
GCGCCCCGGTACTGACGGCGTTGACCGGGCGTATGCCGCGTAAACAGCTGCTGCTGGCGCTGATGGTGCTGTTTACGGCG
GGTAACATACTGGCCTGGCAGGCCCCTGGCTATGAAACGCTGATCCTGGCGCGACTGCTGACTGGTCTGGCGCACGGCGT
GTTTTTTTCTATCGGCTCGACAATCGCCACCAGCCTGGTGGCAAAAGAGAAAGCAGCCTCGGCCACCGCCATTATGTTCG
GTGGCCTGACGGTCGCGCTGGTGACCGGCGTTCCCTTTGGCACCTTTATTGGCCAGCATTTCGGCTGGCGGGAAACCTTC
CTCGCGGTATCGATTCTCGGGGTGATTGCGCTAATCAGCAGTCTGATTCTGGTGCCGAATAACATTCCGGGCCGCGCCAG
CGCCAGCCTGCGCGATCAGCTGAAAGTATTAACCCATCCGCGCCTGCTGATGATCTACGCCATTACCGCGCTGGGCTATG
GCGGCGTGTTTACCGCTTTTACCTTCCTTGCGCCGATGATGCAGGAGCTGGCCGGCTTCAGCCCGTCAGCGGTGAGCTGG
CTCCTGCTGGGCTATGGTGTCTCTGTGGCTATAGGTAACGTGTGGGGCGGCAAACTGGCCGATAAGCATGGCGCCGTCTC
CGCGCTGAAGTTTATCTTCGCTGCGCTGGTTGTGCTGCTGCTGGTCTTCCAGCTGACCGCCAGCGTTCACTATGCCGCGC
TGGCGACAGTGCTGGTGATGGGCGTTTTCGCCTTCGGCAACGTGCCGGGTCTGCAGGTCTATGTGGTGCAAAAAGCAGAG
CAGTATACCCCGGGGGCTGTCGACATCGCTTCCGGCCTGAATATTGCCGCCTTTAACGTCGGCATCGCGCTGGGGTCGAT
CGTCGGTGGACAGACGGTCGAGCGGTACGGTCTGGCGCAGACGCCGTGGATTGGCGCGATGATTGTGCTGGTCGCTTTGC
TGTTGGTGGTCCTGAGCGGACGTTTAGATAAATTGCCACGCCGTTCGGCAGCGCTTTCTCCCGAAGGCTAA

Upstream 100 bases:

>100_bases
GCACCTATAGCAAAATTCTATTGATACTTTGATGGTTTTTGTTATTTATACAACCCTTCATACTACGTGTCATCTTAATC
CTGATGCTACGGAGTAAATT

Downstream 100 bases:

>100_bases
GGGTTTCTCGCAATTTGCATTGAAAGTGTATGGGAAAATCCCTATAACAGAATAACCAGTCGTCGTCGGGCTGGTTTCTG
TTATCGAGGATTAATGCCCA

Product: putative drug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPLALFALTIGAFAIGTTEFVIVGLVPTIAQQLSISLPSAGLLVSIYALGVAIGAPVLTALTGRMPRKQLLLALMVLFTA
GNILAWQAPGYETLILARLLTGLAHGVFFSIGSTIATSLVAKEKAASATAIMFGGLTVALVTGVPFGTFIGQHFGWRETF
LAVSILGVIALISSLILVPNNIPGRASASLRDQLKVLTHPRLLMIYAITALGYGGVFTAFTFLAPMMQELAGFSPSAVSW
LLLGYGVSVAIGNVWGGKLADKHGAVSALKFIFAALVVLLLVFQLTASVHYAALATVLVMGVFAFGNVPGLQVYVVQKAE
QYTPGAVDIASGLNIAAFNVGIALGSIVGGQTVERYGLAQTPWIGAMIVLVALLLVVLSGRLDKLPRRSAALSPEG

Sequences:

>Translated_396_residues
MPLALFALTIGAFAIGTTEFVIVGLVPTIAQQLSISLPSAGLLVSIYALGVAIGAPVLTALTGRMPRKQLLLALMVLFTA
GNILAWQAPGYETLILARLLTGLAHGVFFSIGSTIATSLVAKEKAASATAIMFGGLTVALVTGVPFGTFIGQHFGWRETF
LAVSILGVIALISSLILVPNNIPGRASASLRDQLKVLTHPRLLMIYAITALGYGGVFTAFTFLAPMMQELAGFSPSAVSW
LLLGYGVSVAIGNVWGGKLADKHGAVSALKFIFAALVVLLLVFQLTASVHYAALATVLVMGVFAFGNVPGLQVYVVQKAE
QYTPGAVDIASGLNIAAFNVGIALGSIVGGQTVERYGLAQTPWIGAMIVLVALLLVVLSGRLDKLPRRSAALSPEG
>Mature_395_residues
PLALFALTIGAFAIGTTEFVIVGLVPTIAQQLSISLPSAGLLVSIYALGVAIGAPVLTALTGRMPRKQLLLALMVLFTAG
NILAWQAPGYETLILARLLTGLAHGVFFSIGSTIATSLVAKEKAASATAIMFGGLTVALVTGVPFGTFIGQHFGWRETFL
AVSILGVIALISSLILVPNNIPGRASASLRDQLKVLTHPRLLMIYAITALGYGGVFTAFTFLAPMMQELAGFSPSAVSWL
LLGYGVSVAIGNVWGGKLADKHGAVSALKFIFAALVVLLLVFQLTASVHYAALATVLVMGVFAFGNVPGLQVYVVQKAEQ
YTPGAVDIASGLNIAAFNVGIALGSIVGGQTVERYGLAQTPWIGAMIVLVALLLVVLSGRLDKLPRRSAALSPEG

Specific function: Unknown

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787947, Length=378, Percent_Identity=42.5925925925926, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1786595, Length=399, Percent_Identity=30.5764411027569, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787808, Length=380, Percent_Identity=30.5263157894737, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI145693198, Length=387, Percent_Identity=24.8062015503876, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41085; Mature: 40953

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLALFALTIGAFAIGTTEFVIVGLVPTIAQQLSISLPSAGLLVSIYALGVAIGAPVLTA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LTGRMPRKQLLLALMVLFTAGNILAWQAPGYETLILARLLTGLAHGVFFSIGSTIATSLV
HHCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKEKAASATAIMFGGLTVALVTGVPFGTFIGQHFGWRETFLAVSILGVIALISSLILVPN
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
NIPGRASASLRDQLKVLTHPRLLMIYAITALGYGGVFTAFTFLAPMMQELAGFSPSAVSW
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
LLLGYGVSVAIGNVWGGKLADKHGAVSALKFIFAALVVLLLVFQLTASVHYAALATVLVM
HHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVFAFGNVPGLQVYVVQKAEQYTPGAVDIASGLNIAAFNVGIALGSIVGGQTVERYGLAQ
HHHHHCCCCCEEEEEEECHHCCCCCCEEHHCCCCEEEHHHHHHHHHHHCCCHHHHCCCCC
TPWIGAMIVLVALLLVVLSGRLDKLPRRSAALSPEG
CCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PLALFALTIGAFAIGTTEFVIVGLVPTIAQQLSISLPSAGLLVSIYALGVAIGAPVLTA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LTGRMPRKQLLLALMVLFTAGNILAWQAPGYETLILARLLTGLAHGVFFSIGSTIATSLV
HHCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKEKAASATAIMFGGLTVALVTGVPFGTFIGQHFGWRETFLAVSILGVIALISSLILVPN
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
NIPGRASASLRDQLKVLTHPRLLMIYAITALGYGGVFTAFTFLAPMMQELAGFSPSAVSW
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
LLLGYGVSVAIGNVWGGKLADKHGAVSALKFIFAALVVLLLVFQLTASVHYAALATVLVM
HHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVFAFGNVPGLQVYVVQKAEQYTPGAVDIASGLNIAAFNVGIALGSIVGGQTVERYGLAQ
HHHHHCCCCCEEEEEEECHHCCCCCCEEHHCCCCEEEHHHHHHHHHHHCCCHHHHCCCCC
TPWIGAMIVLVALLLVVLSGRLDKLPRRSAALSPEG
CCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]