Click here to switch to the map view.

The map label for this gene is dgt [H]

Identifier: 152968756

GI number: 152968756

Start: 206010

End: 207524

Strand: Direct

Name: dgt [H]

Synonym: KPN_00175

Alternate gene names: 152968756

Gene position: 206010-207524 (Clockwise)

Preceding gene: 152968752

Following gene: 152968757

Centisome position: 3.88

GC content: 55.05

Gene sequence:

>1515_bases
ATGGCAAAGATTGATTTTCGCAACAAGATAAACTGGCGTCGACGCTTCCGTTCGCCGCCGCGGGTGGAGACGGAGCGCGA
CATCCTGCGGATCTTTGAAAGCGATCGGGGACGGATCGTCAACTCGCCTGCAATCCGCCGCCTGCAGCAAAAAACTCAGG
TCTTCCCGCTCGAGCGCAACGCGGCGGTGCGCACTCGCCTGACCCACTCGCTGGAGGTGCAGCAGGTGGGGCGCTATATC
GCCAAAGAGGTGCTGAGCCGGCTGAAAGAGCTGAGGCTGCTGGAAGAGTATGGCCTGGAAGAGCTGACCGGGCCATTCGA
GAGCGTGGTGGAGATGGCCTGCCTGATGCACGATATCGGCAATCCCCCGTTTGGCCATTTTGGCGAAGCGGCGATTAACG
ACTGGTTCCGTCAGCGCCTGGCGCCCGGCGATGCGCTCGGGCAGCCGCTGACCGACGATCGCTGCGAAGTGCAGGCCTTA
CGCCTGCATGACGGAGAGACATCGCTTAATGCGCTGCGCCGTAAAGTGCGCCAGGATCTCTGCAGCTTTGAGGGCAACGC
GCAGGGCATTCGTCTGGTCCATACGCTAATGCGTATGAACCTGACCTGGGCGCAGGTGGGATGTATCCTGAAATATACTC
GTCCGGCGTGGTGGTCTGAGGAGACGCCGGCCAGCCACAGTTATTTAATGAAGAAACCTGGCTATTATTTAGCCGAAGAA
GAGTATGTCGCGCGTTTGCGTAAAGAACTGGATCTCGCGCCTTACAATCGGTTTCCATTAACCTGGATTATGGAGGCTGC
GGATGACATCTCATATTGCGTCGCGGATCTCGAGGACGCGGTGGAAAAACGTATTTTTAGCGCAGAACAGCTCTATCAGC
ATCTTTACGACGCCTGGGGCAGTCATGAAAAAGGCTCGTTATTTTCGCAGGTAGTAGAAAATGCCTGGGAGAAATCGCGA
GCCAATTATCTGAAGCAGAGCGCGGAAGATCAGTTTTTTATGTATTTGCGGGTGAATACGCTGAATAAGCTGGTGCCCTA
CGCGGCGCGCCGATTTATTGACAACCTGCCGGCAATCTTCACGGGGGACTTTAATCATGCGTTGCTGGAGGACGACAGCG
ATTGCAGTCAGCTACTGGAGCTCTATAAAAATGTGGCGATGAAACAGGTCTTTAGCCATCCGGATGTTGAGCAGCTGGAA
TTGCAGGGCTACCGGGTGATCAGCGGCCTGTTGGATATCTATCAGCCGCTGCTGAAATTATCGCTGGAGGATTTCAGCGA
ATTAGTAGCGCAGGAGCGGGTACGACGTTTACCCATTGCCTCCCGGCTGTATCAGAAACTTTCGACCCGTCACCGGCTGG
CCTATGTTGAAGCGGTAAATAAACTGGCGCGTACGGCGCCCGAATTTGCGCTGATGGAATACTATTATCGCTGCCGTCTG
ATTCAGGACTATATCAGCGGGATGACGGATTTGTATGCGTGGGATGAATATCGGCGACTCATGGCGGTGGAATAG

Upstream 100 bases:

>100_bases
ATAATGCCAATTTTCATAGATTTACTCGCGATGTGTCAGGTTTAGTTGCATAGTCTATCATGCGCTTAAGGGGAAGCGTA
TTGCTCGCGCGGGAGAGGCT

Downstream 100 bases:

>100_bases
GCTGGAGTTTTGTAAAGATGGACAATAAATTTTTACTTTTTCCAGAAACTTAATTCCGGAACTTAGCGTTATAAAATGAC
TCTGATAGTCACGTACACAG

Product: deoxyguanosinetriphosphate triphosphohydrolase

Products: NA

Alternate protein names: dGTP triphosphohydrolase; dGTPase [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MAKIDFRNKINWRRRFRSPPRVETERDILRIFESDRGRIVNSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYI
AKEVLSRLKELRLLEEYGLEELTGPFESVVEMACLMHDIGNPPFGHFGEAAINDWFRQRLAPGDALGQPLTDDRCEVQAL
RLHDGETSLNALRRKVRQDLCSFEGNAQGIRLVHTLMRMNLTWAQVGCILKYTRPAWWSEETPASHSYLMKKPGYYLAEE
EYVARLRKELDLAPYNRFPLTWIMEAADDISYCVADLEDAVEKRIFSAEQLYQHLYDAWGSHEKGSLFSQVVENAWEKSR
ANYLKQSAEDQFFMYLRVNTLNKLVPYAARRFIDNLPAIFTGDFNHALLEDDSDCSQLLELYKNVAMKQVFSHPDVEQLE
LQGYRVISGLLDIYQPLLKLSLEDFSELVAQERVRRLPIASRLYQKLSTRHRLAYVEAVNKLARTAPEFALMEYYYRCRL
IQDYISGMTDLYAWDEYRRLMAVE

Sequences:

>Translated_504_residues
MAKIDFRNKINWRRRFRSPPRVETERDILRIFESDRGRIVNSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYI
AKEVLSRLKELRLLEEYGLEELTGPFESVVEMACLMHDIGNPPFGHFGEAAINDWFRQRLAPGDALGQPLTDDRCEVQAL
RLHDGETSLNALRRKVRQDLCSFEGNAQGIRLVHTLMRMNLTWAQVGCILKYTRPAWWSEETPASHSYLMKKPGYYLAEE
EYVARLRKELDLAPYNRFPLTWIMEAADDISYCVADLEDAVEKRIFSAEQLYQHLYDAWGSHEKGSLFSQVVENAWEKSR
ANYLKQSAEDQFFMYLRVNTLNKLVPYAARRFIDNLPAIFTGDFNHALLEDDSDCSQLLELYKNVAMKQVFSHPDVEQLE
LQGYRVISGLLDIYQPLLKLSLEDFSELVAQERVRRLPIASRLYQKLSTRHRLAYVEAVNKLARTAPEFALMEYYYRCRL
IQDYISGMTDLYAWDEYRRLMAVE
>Mature_503_residues
AKIDFRNKINWRRRFRSPPRVETERDILRIFESDRGRIVNSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYIA
KEVLSRLKELRLLEEYGLEELTGPFESVVEMACLMHDIGNPPFGHFGEAAINDWFRQRLAPGDALGQPLTDDRCEVQALR
LHDGETSLNALRRKVRQDLCSFEGNAQGIRLVHTLMRMNLTWAQVGCILKYTRPAWWSEETPASHSYLMKKPGYYLAEEE
YVARLRKELDLAPYNRFPLTWIMEAADDISYCVADLEDAVEKRIFSAEQLYQHLYDAWGSHEKGSLFSQVVENAWEKSRA
NYLKQSAEDQFFMYLRVNTLNKLVPYAARRFIDNLPAIFTGDFNHALLEDDSDCSQLLELYKNVAMKQVFSHPDVEQLEL
QGYRVISGLLDIYQPLLKLSLEDFSELVAQERVRRLPIASRLYQKLSTRHRLAYVEAVNKLARTAPEFALMEYYYRCRLI
QDYISGMTDLYAWDEYRRLMAVE

Specific function: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs [H]

COG id: COG0232

COG function: function code F; dGTP triphosphohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dGTPase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786355, Length=504, Percent_Identity=83.531746031746, Blast_Score=885, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006261
- InterPro:   IPR020779
- InterPro:   IPR003607 [H]

Pfam domain/function: NA

EC number: =3.1.5.1 [H]

Molecular weight: Translated: 59005; Mature: 58874

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIDFRNKINWRRRFRSPPRVETERDILRIFESDRGRIVNSPAIRRLQQKTQVFPLERN
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCCC
AAVRTRLTHSLEVQQVGRYIAKEVLSRLKELRLLEEYGLEELTGPFESVVEMACLMHDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCC
NPPFGHFGEAAINDWFRQRLAPGDALGQPLTDDRCEVQALRLHDGETSLNALRRKVRQDL
CCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHEECCCCHHHHHHHHHHHHHH
CSFEGNAQGIRLVHTLMRMNLTWAQVGCILKYTRPAWWSEETPASHSYLMKKPGYYLAEE
HCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCH
EYVARLRKELDLAPYNRFPLTWIMEAADDISYCVADLEDAVEKRIFSAEQLYQHLYDAWG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SHEKGSLFSQVVENAWEKSRANYLKQSAEDQFFMYLRVNTLNKLVPYAARRFIDNLPAIF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEE
TGDFNHALLEDDSDCSQLLELYKNVAMKQVFSHPDVEQLELQGYRVISGLLDIYQPLLKL
ECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLEDFSELVAQERVRRLPIASRLYQKLSTRHRLAYVEAVNKLARTAPEFALMEYYYRCRL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
IQDYISGMTDLYAWDEYRRLMAVE
HHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKIDFRNKINWRRRFRSPPRVETERDILRIFESDRGRIVNSPAIRRLQQKTQVFPLERN
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCCC
AAVRTRLTHSLEVQQVGRYIAKEVLSRLKELRLLEEYGLEELTGPFESVVEMACLMHDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCC
NPPFGHFGEAAINDWFRQRLAPGDALGQPLTDDRCEVQALRLHDGETSLNALRRKVRQDL
CCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHEECCCCHHHHHHHHHHHHHH
CSFEGNAQGIRLVHTLMRMNLTWAQVGCILKYTRPAWWSEETPASHSYLMKKPGYYLAEE
HCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCH
EYVARLRKELDLAPYNRFPLTWIMEAADDISYCVADLEDAVEKRIFSAEQLYQHLYDAWG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SHEKGSLFSQVVENAWEKSRANYLKQSAEDQFFMYLRVNTLNKLVPYAARRFIDNLPAIF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEE
TGDFNHALLEDDSDCSQLLELYKNVAMKQVFSHPDVEQLELQGYRVISGLLDIYQPLLKL
ECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLEDFSELVAQERVRRLPIASRLYQKLSTRHRLAYVEAVNKLARTAPEFALMEYYYRCRL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
IQDYISGMTDLYAWDEYRRLMAVE
HHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA