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The map label for this gene is arcD

Identifier: 151222744

GI number: 151222744

Start: 2785305

End: 2786735

Strand: Reverse

Name: arcD

Synonym: NWMN_2532

Alternate gene names: 151222744

Gene position: 2786735-2785305 (Counterclockwise)

Preceding gene: 151222745

Following gene: 151222743

Centisome position: 96.8

GC content: 35.15

Gene sequence:

>1431_bases
ATGAACGAATCAGGAGATAACAAACTCAGTAAATCTTCTTTAATTGGACTAGTTATAGGATCCATGATTGGTGGCGGTGC
GTTCAATATAATGTCTGATATGGGCGGTAAAGCCGGTGGATTAGCCATTATTATTGGTTGGATTATTACAGCTATAGGAA
TGATTTCATTAGCGTTCGTATTTCAAAATTTAACCAATGAACGGCCGGAGCTAGACGGTGGTATTTATAGTTATGCTCAA
GCAGGATTTGGCGATTTTGTAGGATTTATCAGTGCTTGGGGATATTGGTTCTCAGCGTTTTTAGGCAATGTTGCCTATGC
AACACTATTGATGTCAGCAGTAGGTAACTTTTTCCCGATTTTTAAAGGAGGCAACACATTACCAAGTGTTATTGTCGCCT
CGTTACTACTCTGGGGTGTCCATTTCTTGATTTTAAAAGGCGTTGAAACAGCAGCATTTATCAATAGTATTGTTACTGTT
GCAAAGTTAATACCGATTTTACTTGTAATCATATGCATGATAATTGCATTCAATTTTGACACTTTTAAAACAGGCTTTTT
CAGTATGACGTCAGAGGGTGTATTGCCATTTAGTTGGGCGAGCACAATGAGCCAAGTTAAAAGTACGATGCTAGTGACAG
TTTGGGTGTTTATCGGTATCGAAGGTGCAGTAATTTTTTCTAGTAGAGCTAAAAATAAAAAAGATGTAGGTAGTGCCACG
GTTATAGGACTTATATCAGTTTTAATTATCTATTTCTTATTAACTGTATTAGCTCAAGGCGTGATTTTGCAAAATCATAT
TTCGCAATTAGATTCGCCAAGTATGGCACAGGTGCTTGCAACTATTGTAGGTGGTTGGGGATCTACACTTGTAAATATTG
GTTTAATTATTTCGGTACTAGGTGCATGGTTAGGATGGACACTGCTTGCTGGTGAATTACCTTTCATTGTTGCAAAAGAT
GGATTATTTCCAAAATGGTTTGCTAAAGAAAATAAAAATGGAGCACCTGTAAATGCACTGCTTATTACCAATATATTAGT
ACAATTATTTTTAATAAGTATGCTATTTACACAGAGTGCGTATCAATTTGCATTTTCACTAGCATCAAGTGCTATTTTAT
ACCCTTACATGTTCAGTGCATTTTACCAAGTTAAATACACTTTAGAGCATCGACAGCAAGCAACTACTAAACAATGGACG
ATTGGTATCATAGCCTCAATTTATGCTATATGGCTTATATATGCAGCAGGTATCAATTACTTATTATTGACGATGTTACT
TTATATTCCAGCTCTTCTTGTTTATACAATCGTTCAAAAGAATAATCAGACACGTTTGATTAAATCAGACTATATTCTTT
TTATGATTATTATCGTACTTGCAGTTATCGGGTTAATTAAGTTATTGATGGGAACGATAAATGTTTTTTAA

Upstream 100 bases:

>100_bases
GGGGAGTTAATCACTAAATGGAACGATATGAATATGATGTGTCTGATGATATAAGTGTCATGTACAGACACCTCATATTG
GTATTAAAGGAGAAATGAAT

Downstream 100 bases:

>100_bases
AAGGAGCGACAAAAATATGAAAGAGAAAATTGTCATTGCATTAGGCGGTAATGCGATACAGACAACAGAAGCAACAGCTG
AAGCACAACAAACAGCTATT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFVFQNLTNERPELDGGIYSYAQ
AGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPIFKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTV
AKLIPILLVIICMIIAFNFDTFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVLGAWLGWTLLAGELPFIVAKD
GLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSAYQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWT
IGIIASIYAIWLIYAAGINYLLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF

Sequences:

>Translated_476_residues
MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFVFQNLTNERPELDGGIYSYAQ
AGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPIFKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTV
AKLIPILLVIICMIIAFNFDTFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVLGAWLGWTLLAGELPFIVAKD
GLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSAYQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWT
IGIIASIYAIWLIYAAGINYLLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
>Mature_476_residues
MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFVFQNLTNERPELDGGIYSYAQ
AGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPIFKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTV
AKLIPILLVIICMIIAFNFDTFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVLGAWLGWTLLAGELPFIVAKD
GLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSAYQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWT
IGIIASIYAIWLIYAAGINYLLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=442, Percent_Identity=42.9864253393665, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI2367353, Length=456, Percent_Identity=29.6052631578947, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1790575, Length=359, Percent_Identity=25.9052924791086, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786908, Length=432, Percent_Identity=24.0740740740741, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51717; Mature: 51717

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
HHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCHHH
VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
HHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
HHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCHHH
VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
HHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]