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The map label for this gene is arcB

Identifier: 151222745

GI number: 151222745

Start: 2786826

End: 2787836

Strand: Reverse

Name: arcB

Synonym: NWMN_2533

Alternate gene names: 151222745

Gene position: 2787836-2786826 (Counterclockwise)

Preceding gene: 151222746

Following gene: 151222744

Centisome position: 96.84

GC content: 33.14

Gene sequence:

>1011_bases
ATGACAGAAATTCAAAAACCGTATGATTTAAAAGGCAGATCATTATTAAAAGAAAGTGATTTTACCAAAGCAGAATTCGA
AGGACTTATTGATTTTGCAATTACATTAAAAGAGTATAAGAAAAACGGTATTAAGCATCACTACTTATCTGGAAAAAATA
TTGCACTACTATTCGAAAAGAATTCGACGAGAACGCGTGCTGCGTTTACAGTTGCGTCTATTGATTTAGGTGCGCATCCA
GAATTTTTAGGAAAAAATGATATTCAATTAGGCAAAAAAGAATCTGTAGAGGATACTGCGAAAGTATTAGGTAGAATGTT
CGATGGTATTGAATTCCGTGGTTTTTCACAACAAGCTGTTGAAGATTTAGCGAAGTTCTCTGGTGTACCGGTGTGGAATG
GATTAACAGACGATTGGCATCCTACACAAATGTTAGCTGATTTTATGACAATAAAAGAGAATTTTGGATATCTAGAAGGA
ATAAACTTAACTTACGTTGGAGATGGACGTAATAATATTGCGCATTCATTAATGGTAGCAGGTGCTATGTTAGGTGTTAA
TGTAAGAATTTGTACACCTAAATCATTAAATCCAAAAGAGGCATATGTTGATATTGCAAAAGAAAAAGCGAGTCAATATG
GTGGTTCAGTCATGATTACGGATAATATTGCAGAAGCAGTTGAAAATACAGATGCTATATATACAGATGTTTGGGTATCG
ATGGGTGAAGAAAGTGAATTTGAACAACGTATTAATTTATTAAAAGACTATCAAGTGAATCAACAGATGTTTGATTTAAC
AGGTAAAGATTCAACGATATTCTTACATTGTTTACCAGCATTCCATGATACAAATACACTTTATGGACAAGAAATTTATG
AAAAATATGGATTAGCTGAAATGGAAGTTACAGACCAAATCTTTAGAAGTGAACATTCAAAAGTGTTTGATCAAGCTGAA
AATAGAATGCATACAATTAAGGCAGTAATGGCAGCAACATTGGGGAGTTAA

Upstream 100 bases:

>100_bases
GCGAGTTGGTACGTGGACGTGGGGGCCCTAGATGTATGAGTCAACCATTATTCAGAGAAGACATTTAACGTAATAAATTA
TAGAAACGAGGGTGAAAATA

Downstream 100 bases:

>100_bases
TCACTAAATGGAACGATATGAATATGATGTGTCTGATGATATAAGTGTCATGTACAGACACCTCATATTGGTATTAAAGG
AGAAATGAATATGAACGAAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHP
EFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEG
INLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAE
NRMHTIKAVMAATLGS

Sequences:

>Translated_336_residues
MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHP
EFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEG
INLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAE
NRMHTIKAVMAATLGS
>Mature_335_residues
TEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHPE
FLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGI
NLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVSM
GEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAEN
RMHTIKAVMAATLGS

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=37.3493975903614, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI18105007, Length=340, Percent_Identity=26.7647058823529, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=51.6616314199396, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=51.5337423312883, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI48994908, Length=346, Percent_Identity=26.3005780346821, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI2367364, Length=335, Percent_Identity=27.7611940298507, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=179, Percent_Identity=30.7262569832402, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=335, Percent_Identity=34.3283582089552, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6322331, Length=279, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24642586, Length=338, Percent_Identity=27.2189349112426, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OTCC_STAAC (Q5HCR3)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_187444.1
- ProteinModelPortal:   Q5HCR3
- SMR:   Q5HCR3
- STRING:   Q5HCR3
- EnsemblBacteria:   EBSTAT00000009402
- GeneID:   3237045
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2656
- TIGR:   SACOL2656
- eggNOG:   COG0078
- GeneTree:   EBGT00050000023906
- HOGENOM:   HBG579429
- OMA:   NHETVES
- ProtClustDB:   PRK02102
- BioCyc:   SAUR93062:SACOL2656-MONOMER
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 37763; Mature: 37632

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 113-113 BINDING 140-140

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
CCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEC
NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCEEEEEECCCHHHHHHHHHH
GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
HHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCEEHHHHHH
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
CCCCHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCH
MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEC
NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCEEEEEECCCHHHHHHHHHH
GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
HHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCEEHHHHHH
MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
CCCCHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCH
MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA