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The map label for this gene is iolB [H]

Identifier: 150398742

GI number: 150398742

Start: 3764046

End: 3764921

Strand: Reverse

Name: iolB [H]

Synonym: Smed_3559

Alternate gene names: 150398742

Gene position: 3764921-3764046 (Counterclockwise)

Preceding gene: 150398743

Following gene: 150398741

Centisome position: 99.55

GC content: 63.24

Gene sequence:

>876_bases
ATGGGCCAGTCGCAAACGCCGGTATCCCCTCTCCCGGCGGGCGTGGAGAGATGGTACAAATACGAGGAGACCTACATGTC
CAGACTGCTCGTCAAACCGAAAGCACAGACCGGCCTGATGCAGGAGATCACGCCTGAGGGCGCCGGCTGGTCCTATGTCG
GCTTCGCACTTCATCGGCTGTCGCCTGGCGAGATGACCGGTGGCGAGGCGGGGGACAAGGAACTCTGCCTCGTGCTCGTC
AGCGGCAAGGCGAGAATCTCTGTCGATGGCAAGGATTTCGGCGAGCTCGGCGAGCGCATGACGCCCTTCGATGGCCAACC
CTATGCTGTCTATGTGCCGAAGGGCGGCACCTGGCGGGCTGAAGCGACGACCGGCCTTGACCTCGCCATATGCTCCGCGC
CCGGCGGCGAGGGCTTCGAGGCGAAGGTCATCCGCCCCGGCACGCACCCGCAGATGACACGCGGCAAGGGGACCAACACG
CGCTACGTCACCAACATCATGCCGGAGGACGACGGCGCGGCGCAGTCGCTGCTGGTCGTCGAGGTGATCACGCCGGGCGG
TCACACCTCCTCCTACCCACCGCACAAGCATGACGAAGACAATCTACCGGCCGAAAGCTACCTCGAGGAGACTTACTACC
ACCGCCTCAACCCGCCACAGGGTTTTGCCATGCAACGGGTCTATACCGACGACCGCTCCCTGGACGAGACCATGGCCGTG
GAGGACGGCGATGTTACGCTGGTCCCCAAAGGCTACCATCCGGTCGCCGCGATCCACGGCTATGATTCCTACTACCTCAA
CGTCATGGCCGGGCCGAGGCGGATCTGGAAATTCCACAATGCCGGGGAACACGAATGGCTTTTCACCGGCATTTGA

Upstream 100 bases:

>100_bases
GAGAGAATGTAGCCGCCGCTCATCCGGCCGCCGCCTTGTCCCCGCAAGCGGGGAAAAGGAATATGCCGCACCATGCAATT
CACTCCGCCGCCGGGGCAGG

Downstream 100 bases:

>100_bases
GTCGTCCGCGACACCGCTCTGGACGAATGACCCTGCGTACTACAGCGCCGTGCGTCTTATCAGAGGCACAAAGGTCGCTG
TAGCACTTTGATCTGCTGCA

Product: myo-inositol catabolism IolB domain-containing protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MGQSQTPVSPLPAGVERWYKYEETYMSRLLVKPKAQTGLMQEITPEGAGWSYVGFALHRLSPGEMTGGEAGDKELCLVLV
SGKARISVDGKDFGELGERMTPFDGQPYAVYVPKGGTWRAEATTGLDLAICSAPGGEGFEAKVIRPGTHPQMTRGKGTNT
RYVTNIMPEDDGAAQSLLVVEVITPGGHTSSYPPHKHDEDNLPAESYLEETYYHRLNPPQGFAMQRVYTDDRSLDETMAV
EDGDVTLVPKGYHPVAAIHGYDSYYLNVMAGPRRIWKFHNAGEHEWLFTGI

Sequences:

>Translated_291_residues
MGQSQTPVSPLPAGVERWYKYEETYMSRLLVKPKAQTGLMQEITPEGAGWSYVGFALHRLSPGEMTGGEAGDKELCLVLV
SGKARISVDGKDFGELGERMTPFDGQPYAVYVPKGGTWRAEATTGLDLAICSAPGGEGFEAKVIRPGTHPQMTRGKGTNT
RYVTNIMPEDDGAAQSLLVVEVITPGGHTSSYPPHKHDEDNLPAESYLEETYYHRLNPPQGFAMQRVYTDDRSLDETMAV
EDGDVTLVPKGYHPVAAIHGYDSYYLNVMAGPRRIWKFHNAGEHEWLFTGI
>Mature_290_residues
GQSQTPVSPLPAGVERWYKYEETYMSRLLVKPKAQTGLMQEITPEGAGWSYVGFALHRLSPGEMTGGEAGDKELCLVLVS
GKARISVDGKDFGELGERMTPFDGQPYAVYVPKGGTWRAEATTGLDLAICSAPGGEGFEAKVIRPGTHPQMTRGKGTNTR
YVTNIMPEDDGAAQSLLVVEVITPGGHTSSYPPHKHDEDNLPAESYLEETYYHRLNPPQGFAMQRVYTDDRSLDETMAVE
DGDVTLVPKGYHPVAAIHGYDSYYLNVMAGPRRIWKFHNAGEHEWLFTGI

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 32027; Mature: 31896

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQSQTPVSPLPAGVERWYKYEETYMSRLLVKPKAQTGLMQEITPEGAGWSYVGFALHRL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHCCCCCCCCCHHHHHHHHC
SPGEMTGGEAGDKELCLVLVSGKARISVDGKDFGELGERMTPFDGQPYAVYVPKGGTWRA
CCCCCCCCCCCCCEEEEEEECCCEEEEECCCCHHHHHCCCCCCCCCCEEEEECCCCCEEE
EATTGLDLAICSAPGGEGFEAKVIRPGTHPQMTRGKGTNTRYVTNIMPEDDGAAQSLLVV
ECCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEE
EVITPGGHTSSYPPHKHDEDNLPAESYLEETYYHRLNPPQGFAMQRVYTDDRSLDETMAV
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHEEE
EDGDVTLVPKGYHPVAAIHGYDSYYLNVMAGPRRIWKFHNAGEHEWLFTGI
CCCCEEEEECCCCCEEEEECCCCEEEEEEECCHHHHEECCCCCCCEEEECC
>Mature Secondary Structure 
GQSQTPVSPLPAGVERWYKYEETYMSRLLVKPKAQTGLMQEITPEGAGWSYVGFALHRL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHCCCCCCCCCHHHHHHHHC
SPGEMTGGEAGDKELCLVLVSGKARISVDGKDFGELGERMTPFDGQPYAVYVPKGGTWRA
CCCCCCCCCCCCCEEEEEEECCCEEEEECCCCHHHHHCCCCCCCCCCEEEEECCCCCEEE
EATTGLDLAICSAPGGEGFEAKVIRPGTHPQMTRGKGTNTRYVTNIMPEDDGAAQSLLVV
ECCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEE
EVITPGGHTSSYPPHKHDEDNLPAESYLEETYYHRLNPPQGFAMQRVYTDDRSLDETMAV
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHEEE
EDGDVTLVPKGYHPVAAIHGYDSYYLNVMAGPRRIWKFHNAGEHEWLFTGI
CCCCEEEEECCCCCEEEEECCCCEEEEEEECCHHHHEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA