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The map label for this gene is iolE [H]

Identifier: 150398743

GI number: 150398743

Start: 3765010

End: 3765912

Strand: Reverse

Name: iolE [H]

Synonym: Smed_3560

Alternate gene names: 150398743

Gene position: 3765912-3765010 (Counterclockwise)

Preceding gene: 150398744

Following gene: 150398742

Centisome position: 99.58

GC content: 60.13

Gene sequence:

>903_bases
ATGATCCGCTACGGAACCAACCCGATCGCCTGGAGCAATGACGACGACCACTCGATCGGGGCGCATCTGACCCTCGAGGA
CTGCCTTTCGGATTGTCAGAAAATCGGCTTCGACGGCATCGAAAAGGGCCACAAGATGCCTTCCGATCCGGAAGCGCTGA
AGCGGAAGCTTGGCTCGTATGATCTCGTCTTCGTCTCGGGCTGGCACTCGACCAATCTGCTGACCCATGATGTCGAGGCG
GAGAAGAAGGCTATCCAGCCGCATCTCGACCTTTTGAAGCACAATGGCTGCAAGGTGGCGATCGTCTGCGAAACCTCGAA
CGCCATCCATGGGGACGATTCCAAGTCGCTCGTCAAGGATAAGCCGGTGCTGGCAGCGGACGAGTGGAAGACGTTCGGCG
CCGATCTCGAGGCGATCGCCGGATATTGCGCCAGCCAGGGCATCGACCTGGTCTATCATCACCACATGGGCACCATCGTC
CAGACCGGCGAAGAGGTCGACCTGTTGATGCAGAACACGGGTCCGGCGACCAAGCTGCTGCTCGACACCGGTCACGCCTG
GTTCGGCGGCTCCGACCCGGCGGAACTGGCGCGGAAATATATGGGCCGCGTTCGCCACATTCATTGCAAGAACGTCCGCC
CGGCCGTCCGGAAGGTGGTCGAAAGCGAAGGATTGTCCTTCCTTGAAGGCGTACGCCGCGGCGTCTTTACCGTTCCGGGC
GATTCCGAGGGCGGCATCGATTTCCTGCCGGTCCTCAAAATCGCGGCCGAACACGACTATGACGGCTGGCTTGTGATAGA
GGCTGAGCAGGATTCGGCCGTGCGCAACCCCTTCGACTACCAATCTCTGGGGCTGAAGTCATTGAAGGCATTGGCGAAGG
AGGCGGGGCTGGAGAGAATGTAG

Upstream 100 bases:

>100_bases
GTCACAGCGGTTTGGTTGACCTACTGCGGCCTCCTTCGCGCACCAAAACAAAACCACGAACCAACGGCCTCCGGCAGACA
AGACAACAGAGAGCAAGCAC

Downstream 100 bases:

>100_bases
CCGCCGCTCATCCGGCCGCCGCCTTGTCCCCGCAAGCGGGGAAAAGGAATATGCCGCACCATGCAATTCACTCCGCCGCC
GGGGCAGGATGGGCCAGTCG

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIRYGTNPIAWSNDDDHSIGAHLTLEDCLSDCQKIGFDGIEKGHKMPSDPEALKRKLGSYDLVFVSGWHSTNLLTHDVEA
EKKAIQPHLDLLKHNGCKVAIVCETSNAIHGDDSKSLVKDKPVLAADEWKTFGADLEAIAGYCASQGIDLVYHHHMGTIV
QTGEEVDLLMQNTGPATKLLLDTGHAWFGGSDPAELARKYMGRVRHIHCKNVRPAVRKVVESEGLSFLEGVRRGVFTVPG
DSEGGIDFLPVLKIAAEHDYDGWLVIEAEQDSAVRNPFDYQSLGLKSLKALAKEAGLERM

Sequences:

>Translated_300_residues
MIRYGTNPIAWSNDDDHSIGAHLTLEDCLSDCQKIGFDGIEKGHKMPSDPEALKRKLGSYDLVFVSGWHSTNLLTHDVEA
EKKAIQPHLDLLKHNGCKVAIVCETSNAIHGDDSKSLVKDKPVLAADEWKTFGADLEAIAGYCASQGIDLVYHHHMGTIV
QTGEEVDLLMQNTGPATKLLLDTGHAWFGGSDPAELARKYMGRVRHIHCKNVRPAVRKVVESEGLSFLEGVRRGVFTVPG
DSEGGIDFLPVLKIAAEHDYDGWLVIEAEQDSAVRNPFDYQSLGLKSLKALAKEAGLERM
>Mature_300_residues
MIRYGTNPIAWSNDDDHSIGAHLTLEDCLSDCQKIGFDGIEKGHKMPSDPEALKRKLGSYDLVFVSGWHSTNLLTHDVEA
EKKAIQPHLDLLKHNGCKVAIVCETSNAIHGDDSKSLVKDKPVLAADEWKTFGADLEAIAGYCASQGIDLVYHHHMGTIV
QTGEEVDLLMQNTGPATKLLLDTGHAWFGGSDPAELARKYMGRVRHIHCKNVRPAVRKVVESEGLSFLEGVRRGVFTVPG
DSEGGIDFLPVLKIAAEHDYDGWLVIEAEQDSAVRNPFDYQSLGLKSLKALAKEAGLERM

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 32922; Mature: 32922

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRYGTNPIAWSNDDDHSIGAHLTLEDCLSDCQKIGFDGIEKGHKMPSDPEALKRKLGSY
CCEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCC
DLVFVSGWHSTNLLTHDVEAEKKAIQPHLDLLKHNGCKVAIVCETSNAIHGDDSKSLVKD
EEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHC
KPVLAADEWKTFGADLEAIAGYCASQGIDLVYHHHMGTIVQTGEEVDLLMQNTGPATKLL
CCCEECCCHHHHCCCHHHHHHHHHHCCCEEEEECCCCHHHHCCCHHEEEECCCCCCEEEE
LDTGHAWFGGSDPAELARKYMGRVRHIHCKNVRPAVRKVVESEGLSFLEGVRRGVFTVPG
EECCCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCHHHHHHHHCCEEECCC
DSEGGIDFLPVLKIAAEHDYDGWLVIEAEQDSAVRNPFDYQSLGLKSLKALAKEAGLERM
CCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIRYGTNPIAWSNDDDHSIGAHLTLEDCLSDCQKIGFDGIEKGHKMPSDPEALKRKLGSY
CCEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCC
DLVFVSGWHSTNLLTHDVEAEKKAIQPHLDLLKHNGCKVAIVCETSNAIHGDDSKSLVKD
EEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHC
KPVLAADEWKTFGADLEAIAGYCASQGIDLVYHHHMGTIVQTGEEVDLLMQNTGPATKLL
CCCEECCCHHHHCCCHHHHHHHHHHCCCEEEEECCCCHHHHCCCHHEEEECCCCCCEEEE
LDTGHAWFGGSDPAELARKYMGRVRHIHCKNVRPAVRKVVESEGLSFLEGVRRGVFTVPG
EECCCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCHHHHHHHHCCEEECCC
DSEGGIDFLPVLKIAAEHDYDGWLVIEAEQDSAVRNPFDYQSLGLKSLKALAKEAGLERM
CCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]