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The map label for this gene is murQ [H]

Identifier: 150398595

GI number: 150398595

Start: 3613582

End: 3614478

Strand: Reverse

Name: murQ [H]

Synonym: Smed_3406

Alternate gene names: 150398595

Gene position: 3614478-3613582 (Counterclockwise)

Preceding gene: 150398600

Following gene: 150398594

Centisome position: 95.57

GC content: 65.55

Gene sequence:

>897_bases
ATGCAGCCAGCAAGGACCGAAGAGCGCCACGACAATGCAAAGGGTCTGGACGTCATGCGCCCGGAGATCGCTCTTCGATT
GCTTGCAGCCGGTCAACAGGAAGCGGCGAAGGCCGTGGACCGGGCCATCGAGCCAATTTCGGCGGCGGCCCGTCTTGCCG
CCGACAGCCTCGCCTCCGGCGGCCGGCTTGCCTATGCGGGCGCCGGAAGCTCCGGACTGATGGCCATGGCGGATGCGCTC
GAGCTGCCGGGCACCTACGGCATAGCCCGGGAACAGATCGCCATTCTCATCGCCGGCGGGGCCGCAAGCCTTACCGATCT
TGCGGGCGGCTACGAGGACGATATGGAGCTTGCGCGCTTCGATGTCCGGGGCGCCGGCATAGGGGCTGGCGACTGTTTGA
TTTCGGTATCCGCCAGCGGCTTCACGCCCTATGCAATCGCCGCTGCCGAAGAGGCCAGGACACGCGGCGCGCGTATCATC
GCCATGGCCAACAATGCCGGCGCACCGCTGCTCCAGGCCGCCGATGTCGCAATTCTCATCGAGACACCGCCGGAGATCGT
ATCCGGTTCGACGCGCATGGGCGCCGGAACCGCTCAGAAAATCGCCTTTAACATGTTCTCGACCATGATCGGCATCCATC
TCGGCCACGTGCTCGATGGCCACATGGTCAATCTACGTGCCGACAACATAAAGCTGCGCGGCCGCGCAATCCGGATCGTC
TGCGACATCACCCGCGTCACCGCGGCCGAGGCGGAGAGGCTGCTCGACCTTGCCGGCGGCTCGGTCAAACTGGCGATCCT
GCTGGCCTCCGGAGCGAGGGATGCCGCCCATGCCGAACACGCCCTAGAGCGTGCCGATCACAATCTGCGCCGGGCGATCG
CCATCGTTCAGGCCTGA

Upstream 100 bases:

>100_bases
TGTATAATTCTACCCATCGTCGTTTATTCGCTTGTAAGTTAAAATTTTCCTAGACAAGTGGTATTTTTTTGGCCTTAATC
CCAGAAGAGGAGAACGATGC

Downstream 100 bases:

>100_bases
AGAATAGACTGCGCACCAGAACAGCGCGACCAAGCGCTAAAAAAGGGGAGAAAATGCATGACCCGCACGACAATGAAAGG
CCTACTGCTTGCATCGAGCA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQPARTEERHDNAKGLDVMRPEIALRLLAAGQQEAAKAVDRAIEPISAAARLAADSLASGGRLAYAGAGSSGLMAMADAL
ELPGTYGIAREQIAILIAGGAASLTDLAGGYEDDMELARFDVRGAGIGAGDCLISVSASGFTPYAIAAAEEARTRGARII
AMANNAGAPLLQAADVAILIETPPEIVSGSTRMGAGTAQKIAFNMFSTMIGIHLGHVLDGHMVNLRADNIKLRGRAIRIV
CDITRVTAAEAERLLDLAGGSVKLAILLASGARDAAHAEHALERADHNLRRAIAIVQA

Sequences:

>Translated_298_residues
MQPARTEERHDNAKGLDVMRPEIALRLLAAGQQEAAKAVDRAIEPISAAARLAADSLASGGRLAYAGAGSSGLMAMADAL
ELPGTYGIAREQIAILIAGGAASLTDLAGGYEDDMELARFDVRGAGIGAGDCLISVSASGFTPYAIAAAEEARTRGARII
AMANNAGAPLLQAADVAILIETPPEIVSGSTRMGAGTAQKIAFNMFSTMIGIHLGHVLDGHMVNLRADNIKLRGRAIRIV
CDITRVTAAEAERLLDLAGGSVKLAILLASGARDAAHAEHALERADHNLRRAIAIVQA
>Mature_298_residues
MQPARTEERHDNAKGLDVMRPEIALRLLAAGQQEAAKAVDRAIEPISAAARLAADSLASGGRLAYAGAGSSGLMAMADAL
ELPGTYGIAREQIAILIAGGAASLTDLAGGYEDDMELARFDVRGAGIGAGDCLISVSASGFTPYAIAAAEEARTRGARII
AMANNAGAPLLQAADVAILIETPPEIVSGSTRMGAGTAQKIAFNMFSTMIGIHLGHVLDGHMVNLRADNIKLRGRAIRIV
CDITRVTAAEAERLLDLAGGSVKLAILLASGARDAAHAEHALERADHNLRRAIAIVQA

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=256, Percent_Identity=37.109375, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30757; Mature: 30757

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPARTEERHDNAKGLDVMRPEIALRLLAAGQQEAAKAVDRAIEPISAAARLAADSLASG
CCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GRLAYAGAGSSGLMAMADALELPGTYGIAREQIAILIAGGAASLTDLAGGYEDDMELARF
CEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHE
DVRGAGIGAGDCLISVSASGFTPYAIAAAEEARTRGARIIAMANNAGAPLLQAADVAILI
ECCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHCCCEEEEEEECCCCCCCEEECCEEEEE
ETPPEIVSGSTRMGAGTAQKIAFNMFSTMIGIHLGHVLDGHMVNLRADNIKLRGRAIRIV
ECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEEECCEEEEEE
CDITRVTAAEAERLLDLAGGSVKLAILLASGARDAAHAEHALERADHNLRRAIAIVQA
EEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MQPARTEERHDNAKGLDVMRPEIALRLLAAGQQEAAKAVDRAIEPISAAARLAADSLASG
CCCCCCCHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GRLAYAGAGSSGLMAMADALELPGTYGIAREQIAILIAGGAASLTDLAGGYEDDMELARF
CEEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHE
DVRGAGIGAGDCLISVSASGFTPYAIAAAEEARTRGARIIAMANNAGAPLLQAADVAILI
ECCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHCCCEEEEEEECCCCCCCEEECCEEEEE
ETPPEIVSGSTRMGAGTAQKIAFNMFSTMIGIHLGHVLDGHMVNLRADNIKLRGRAIRIV
ECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEEECCEEEEEE
CDITRVTAAEAERLLDLAGGSVKLAILLASGARDAAHAEHALERADHNLRRAIAIVQA
EEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA