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The map label for this gene is cutC

Identifier: 150398600

GI number: 150398600

Start: 3618646

End: 3619383

Strand: Reverse

Name: cutC

Synonym: Smed_3411

Alternate gene names: 150398600

Gene position: 3619383-3618646 (Counterclockwise)

Preceding gene: 150398601

Following gene: 150398595

Centisome position: 95.7

GC content: 67.89

Gene sequence:

>738_bases
ATGAACCGGATATTGCTCGAGGTCTGCGTCGACGATCCCGACGGGCTGGAGGCAGCCGTTGCCGGAGGTGCGGACCGCGT
CGAGCTCTGCTCGGCTCTTTGCGCCGGAGGGTTGACCCCCAGCCCCGGCCTGATGTCCGCCGCCGGCATGCCGCCGGTGC
CTGTCTATGCGATGATCCGGCCGCGGGCGGGCGATTTCGTCTATGACGCTGCCGATCTCGAGGTGATGCGCCGGGACATC
GATGCGGCACGTGCTGCCGGGCTTGCGGGCGTGGTGCTCGGCGCGTCGCGCGCCGACGGCCGCCTCGACGCCCGCATGCT
GACAAAGCTCGCCGGCCACGCGGCGGGAATGGGGCTGACGCTGCACCGCGCCTTCGATCTGGTGCCTGATTTCGCCGAGG
CGCTGGAGATCGCCGTCGAACTCGGCTTCGAACGCATCCTGACTTCGGGGGGCGCGAAAACGGCACCAGAAGCGGTCGAA
ATTCTGGAAAAGCTCATCGCGGCGGCGTCAGGACGGATCTCGATCATGCCGGGTTCGGGCATCACCAGCAACACGGCCGG
AACGCTCCTGCCGCGGCTCGCCATAGCCGAGGTCCATTCGTCCTGCTCGACTTCTGAGCCGGCTAATGACATGCGGCTCG
TGGAGATGGGATTCGCCGCGCCGGAGCGTCGCCGCACCGACGCGGCAAAGATCAGGGCAATGCGGGCGTGCCTCGATGCT
CTGGCGGCGAAGGCTTGA

Upstream 100 bases:

>100_bases
TTCTCAGGCGCTTCGACCGACCGCTCGTGGTGCGTGGCGAGTGTAGGGTAGAGCCGGGGCTGATCGGCGCTGCGCTGCTC
GGTTGCGAAGGGAGATCGGC

Downstream 100 bases:

>100_bases
GCACGAGCTGTGACGCTTCCGGCGGCGTCCGCCCCCCTCGGCTCAAAGCTCCTCTCTCCGCTTGCGGTGCAATCTTGCAG
CGCATCGCACCGGCAAGGTG

Product: CutC family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNRILLEVCVDDPDGLEAAVAGGADRVELCSALCAGGLTPSPGLMSAAGMPPVPVYAMIRPRAGDFVYDAADLEVMRRDI
DAARAAGLAGVVLGASRADGRLDARMLTKLAGHAAGMGLTLHRAFDLVPDFAEALEIAVELGFERILTSGGAKTAPEAVE
ILEKLIAAASGRISIMPGSGITSNTAGTLLPRLAIAEVHSSCSTSEPANDMRLVEMGFAAPERRRTDAAKIRAMRACLDA
LAAKA

Sequences:

>Translated_245_residues
MNRILLEVCVDDPDGLEAAVAGGADRVELCSALCAGGLTPSPGLMSAAGMPPVPVYAMIRPRAGDFVYDAADLEVMRRDI
DAARAAGLAGVVLGASRADGRLDARMLTKLAGHAAGMGLTLHRAFDLVPDFAEALEIAVELGFERILTSGGAKTAPEAVE
ILEKLIAAASGRISIMPGSGITSNTAGTLLPRLAIAEVHSSCSTSEPANDMRLVEMGFAAPERRRTDAAKIRAMRACLDA
LAAKA
>Mature_245_residues
MNRILLEVCVDDPDGLEAAVAGGADRVELCSALCAGGLTPSPGLMSAAGMPPVPVYAMIRPRAGDFVYDAADLEVMRRDI
DAARAAGLAGVVLGASRADGRLDARMLTKLAGHAAGMGLTLHRAFDLVPDFAEALEIAVELGFERILTSGGAKTAPEAVE
ILEKLIAAASGRISIMPGSGITSNTAGTLLPRLAIAEVHSSCSTSEPANDMRLVEMGFAAPERRRTDAAKIRAMRACLDA
LAAKA

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=243, Percent_Identity=39.917695473251, Blast_Score=164, Evalue=5e-41,
Organism=Escherichia coli, GI87081995, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17556905, Length=241, Percent_Identity=35.6846473029046, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21355415, Length=202, Percent_Identity=39.1089108910891, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_SINMW (A6UF02)

Other databases:

- EMBL:   CP000738
- RefSeq:   YP_001329067.1
- ProteinModelPortal:   A6UF02
- SMR:   A6UF02
- STRING:   A6UF02
- GeneID:   5324295
- GenomeReviews:   CP000738_GR
- KEGG:   smd:Smed_3411
- eggNOG:   COG3142
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- ProtClustDB:   CLSK2752248
- BioCyc:   SMED366394:SMED_3411-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 25295; Mature: 25295

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRILLEVCVDDPDGLEAAVAGGADRVELCSALCAGGLTPSPGLMSAAGMPPVPVYAMIR
CCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEC
PRAGDFVYDAADLEVMRRDIDAARAAGLAGVVLGASRADGRLDARMLTKLAGHAAGMGLT
CCCCCEEECHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHH
LHRAFDLVPDFAEALEIAVELGFERILTSGGAKTAPEAVEILEKLIAAASGRISIMPGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCC
ITSNTAGTLLPRLAIAEVHSSCSTSEPANDMRLVEMGFAAPERRRTDAAKIRAMRACLDA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCCHHHHHHHHHHHHHHHHHHH
LAAKA
HHCCC
>Mature Secondary Structure
MNRILLEVCVDDPDGLEAAVAGGADRVELCSALCAGGLTPSPGLMSAAGMPPVPVYAMIR
CCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEC
PRAGDFVYDAADLEVMRRDIDAARAAGLAGVVLGASRADGRLDARMLTKLAGHAAGMGLT
CCCCCEEECHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHH
LHRAFDLVPDFAEALEIAVELGFERILTSGGAKTAPEAVEILEKLIAAASGRISIMPGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCC
ITSNTAGTLLPRLAIAEVHSSCSTSEPANDMRLVEMGFAAPERRRTDAAKIRAMRACLDA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHCCCCCHHHHHHHHHHHHHHHHHHH
LAAKA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA