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The map label for this gene is add [H]

Identifier: 150398533

GI number: 150398533

Start: 3544217

End: 3545191

Strand: Reverse

Name: add [H]

Synonym: Smed_3344

Alternate gene names: 150398533

Gene position: 3545191-3544217 (Counterclockwise)

Preceding gene: 150398534

Following gene: 150398532

Centisome position: 93.74

GC content: 64.21

Gene sequence:

>975_bases
TTGACCGCTCATCTGAAGAAGGCAGAGCTGCACTGCCACATCGAAGGCGCGACGCCGCCGGAACTGGCGGTGAGACAGGC
TCGGAAATACGGCGTCGATACCGGCACAATCATCCGGGACGGTGCCTATGTCTGGGAGGATTTCACCAGCTTCGTGAAGT
GCTACGATGCCGTGGCTTCGCTGTTTCGCACCGAGGGGGATTATGCGCTTCTCGCCGAGGCCTATCTGACGGAGCTTGCA
GAAGCCGGCACGATCTATAGCGAGATCATCGTCTCGCCCGACCACGGCAACACGGTCGGCCTCGGGGCAGATGCATATCT
CGAGGGGCTGGCCGCCGGCATGGAAGCCGCGAAGGCCAGAAAGGGGATCGAATCCCGCATGCTGATCACCGGCATCCGGC
ACCTCGGCCCGGAAGCAGTCGTCAGGACCGCGGAATATGCAGCCTCGCATCGGCATCCGCTCGTCACCGGTTTCAACCTG
GCCGGCGAGGAGCGCATGCATAGCGTGGCTGAATTTTCCCGTGCCTTCGACATCGTCCGCGATGCCGGTCTCGGCCTGAC
CATTCACGCCGGCGAGCTTTCCGGCGCCTTCAGCGTGCGCGACGCTCTGGACCACGTCCGCCCCGCCCGGATCAGTCACG
GTGTCCGGGCGATCGAGGACACGGACCTCGTCAGGCGGCTTGCCGATGAGGGCGTGGTGCTCGAAGTCTGCCCCGGCTCG
AATATCGCGTTGAAGGTGTTTCCGGATTTCCCCTCGCATCCGCTGCGGCGGCTTTACGACGCCGGCGTCCGCGTGACGCT
CAACTCCGACGATCCCCCCTTCTTCCATACCTCGCTGGCGCAGGAATACGAGATCGCCGCCCACGCCATGGGATTCTCCG
ACGGCGAGATCGACCGGATGACGAGAACGGCGCTCGAAGCCGCCTTCGTGGACGAGCCGACGCGAGAGAGGCTGCTGGCT
GCGTTGCACATCTGA

Upstream 100 bases:

>100_bases
GGAGCCGCTCCGTCGGTATTGTCGGGAGCTTCGCACATATCGGTGAAACCGTTGCAAGTCATCTCGGAATTGACCCCGGC
CCGCATGGGAGGAGCCTCAT

Downstream 100 bases:

>100_bases
TTGCCGGGCGATTGGCCTCGCCCTCGCCGCTCAAAACGGAAGAAGGTGTCGGCGGGGGAATAGGAGCGCCATCTGCCATC
AACTTCCACCTACACCCTTG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTAHLKKAELHCHIEGATPPELAVRQARKYGVDTGTIIRDGAYVWEDFTSFVKCYDAVASLFRTEGDYALLAEAYLTELA
EAGTIYSEIIVSPDHGNTVGLGADAYLEGLAAGMEAAKARKGIESRMLITGIRHLGPEAVVRTAEYAASHRHPLVTGFNL
AGEERMHSVAEFSRAFDIVRDAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRAIEDTDLVRRLADEGVVLEVCPGS
NIALKVFPDFPSHPLRRLYDAGVRVTLNSDDPPFFHTSLAQEYEIAAHAMGFSDGEIDRMTRTALEAAFVDEPTRERLLA
ALHI

Sequences:

>Translated_324_residues
MTAHLKKAELHCHIEGATPPELAVRQARKYGVDTGTIIRDGAYVWEDFTSFVKCYDAVASLFRTEGDYALLAEAYLTELA
EAGTIYSEIIVSPDHGNTVGLGADAYLEGLAAGMEAAKARKGIESRMLITGIRHLGPEAVVRTAEYAASHRHPLVTGFNL
AGEERMHSVAEFSRAFDIVRDAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRAIEDTDLVRRLADEGVVLEVCPGS
NIALKVFPDFPSHPLRRLYDAGVRVTLNSDDPPFFHTSLAQEYEIAAHAMGFSDGEIDRMTRTALEAAFVDEPTRERLLA
ALHI
>Mature_323_residues
TAHLKKAELHCHIEGATPPELAVRQARKYGVDTGTIIRDGAYVWEDFTSFVKCYDAVASLFRTEGDYALLAEAYLTELAE
AGTIYSEIIVSPDHGNTVGLGADAYLEGLAAGMEAAKARKGIESRMLITGIRHLGPEAVVRTAEYAASHRHPLVTGFNLA
GEERMHSVAEFSRAFDIVRDAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRAIEDTDLVRRLADEGVVLEVCPGSN
IALKVFPDFPSHPLRRLYDAGVRVTLNSDDPPFFHTSLAQEYEIAAHAMGFSDGEIDRMTRTALEAAFVDEPTRERLLAA
LHI

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=341, Percent_Identity=24.633431085044, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1787910, Length=322, Percent_Identity=27.3291925465839, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32565969, Length=213, Percent_Identity=24.4131455399061, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538512, Length=213, Percent_Identity=24.4131455399061, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324188, Length=329, Percent_Identity=26.7477203647416, Blast_Score=129, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24645260, Length=321, Percent_Identity=25.2336448598131, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45553183, Length=286, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17737615, Length=286, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 35291; Mature: 35160

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHLKKAELHCHIEGATPPELAVRQARKYGVDTGTIIRDGAYVWEDFTSFVKCYDAVAS
CCCCCEECEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
LFRTEGDYALLAEAYLTELAEAGTIYSEIIVSPDHGNTVGLGADAYLEGLAAGMEAAKAR
HHHCCCCHHHHHHHHHHHHHHHCCHHHHEEECCCCCCEEECCHHHHHHHHHHHHHHHHHH
KGIESRMLITGIRHLGPEAVVRTAEYAASHRHPLVTGFNLAGEERMHSVAEFSRAFDIVR
HCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
DAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRAIEDTDLVRRLADEGVVLEVCPGS
HCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCC
NIALKVFPDFPSHPLRRLYDAGVRVTLNSDDPPFFHTSLAQEYEIAAHAMGFSDGEIDRM
CEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
TRTALEAAFVDEPTRERLLAALHI
HHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TAHLKKAELHCHIEGATPPELAVRQARKYGVDTGTIIRDGAYVWEDFTSFVKCYDAVAS
CCCCEECEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
LFRTEGDYALLAEAYLTELAEAGTIYSEIIVSPDHGNTVGLGADAYLEGLAAGMEAAKAR
HHHCCCCHHHHHHHHHHHHHHHCCHHHHEEECCCCCCEEECCHHHHHHHHHHHHHHHHHH
KGIESRMLITGIRHLGPEAVVRTAEYAASHRHPLVTGFNLAGEERMHSVAEFSRAFDIVR
HCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
DAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRAIEDTDLVRRLADEGVVLEVCPGS
HCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCC
NIALKVFPDFPSHPLRRLYDAGVRVTLNSDDPPFFHTSLAQEYEIAAHAMGFSDGEIDRM
CEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
TRTALEAAFVDEPTRERLLAALHI
HHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]