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The map label for this gene is zraS [C]

Identifier: 150398471

GI number: 150398471

Start: 3469459

End: 3471963

Strand: Reverse

Name: zraS [C]

Synonym: Smed_3279

Alternate gene names: 150398471

Gene position: 3471963-3469459 (Counterclockwise)

Preceding gene: 150398472

Following gene: 150398470

Centisome position: 91.8

GC content: 58.96

Gene sequence:

>2505_bases
ATGACAGCGTTGCGGGTCCCGAACCGGCTTGGATCCCACGTTTCAGTGCGGTTGCGGCTGTGGCTGGCATTGGCGGCACT
GGCACTTGCCACGCTGGTTGTCGGCGGCGCAAGCTGGGCGACGCTCCGGCAGACTTCCACGCGACTTGACCGTCTGCATG
ACCAAAGCCTTGCCAGAGTCGATGATGCGCTAACCCTTTCGCGAAAGGCTACGGCTGTGGCTGCCCGTGCGCCCTTTCTG
CTGACAATAGAAAGCCCGTTTCGCCTGCAGGTGGAGGCAGGCATCTCAAAAACCCTGCTTGCGGATATAAGACGTCATCT
GGACGGCCAGAACGCGTTGTTTGACAAGCTGCTGACCGAGATGGGCGGCAGTATCGACGAACTGACCACGCTATCTCTGC
ACCGTATCGAGCTGACCGACCGCATCTTGCGGCTGAATGCCGTGCTTGCGATAGAAGAGCGGCGTTTCGCGGCGCTGGCC
CGCGAGAAGCAAAAACCTTTGGGTCAGCGTGAGCAATGGCTGACAATGCAGCGTATTTCCGCGGTGCTTTTGGGCGCGGG
CCGCTCGGAAAATCTGATCGGTATCGGTGAGTTTCATCGGAACTATCGTGCGCTGATCGTCGAGCTCGAGGAAGACGAAA
AGCCGCTGATACAATCTCAACTGTTGAAATTGCAGGAGATCGCGTCGGGCAGGGACGGCCTGTTTGAATTGCGCCGGGCG
GAAATAGGCCGGCGCATTCGCGCCGAGGCAGCCATGAACCGCATTCGGCACAGCACCGAAGTTATCAACAATCATGCAGC
CGAGATTACAGCGACAGCGCAGGCCAATATAATCACCGAACGTGAGCGAACCATTTCGGCCATCGCCTTCGCCAGCGGCA
TAATCGTGATCGCCGTCGTCCTGTCGATTTTAATGGCCGTCATGGCGGCAGCCTTCGTCTCGGGTCACGTTACCGCGAAT
CTGCGGGCCATTTCCGATGCCATGATGCGGCTGGCGGTCGGGGATCGCTCGATCAGGCTTCCGCGTGGTGAACATGCCGG
GTACGAGATTGGCAAGTTGTTTCACGCTTTTCGGGCCTTTCGCGCCAATACGTTGCGGCTGGACAGGTCGAACCGGCAGC
TAGCGCAGAAAAACGCGTTATTCGAAAATCTGTATAACGACATGTCGGACGGGCTGGCGATTCTGTCCAACGATGAAAAA
ATCATCGCGCATAACAACCGGTTGCCGAAACTTCTGTCCCTGAGAGCAACAACCGTCCGCACCAGAACATCCTTGGCGCA
GCTGCTTGAGGCGGGTAACTGGACGCGGTGGGACCGGTCAGAGGGTTTCGCTGACCTGCATCACCCCTCCGGCACTGTGG
TCGAACTGCGCCAGAGCCCGCTGAGTACGGGCGGGGCGGTTGCCCTTCTGTCCGACGTGTCCGAGCGCCGTCAGTTGGAA
GAACATCTGCAAAGCGTCCGTCGAATCGAGGGCTTGGGCAGGATCGCCGGTGAAGTGGCGCATGATTTCGGCAATATCCT
GTCGACGGTCTCGACCAACCTGCATCTGCTGGAAAACGCGACGCCGGAGCGGGCGGCTCATTTGCATCACACCCTTGCCA
ATGCGCTGGATCTGGGCACCAGCCTTACCCAGCGGCTGCTGGCCTTTGCCCGCCGCCAGAGGCTCGACCCGGAGATCATG
AACCTCAACGAACTCGTCACCGGTATTGAGGACCTGATCGCTCTGGCGCTGGACGATCGGATATCGCTCCATATTTTTCC
GGCATCGGAACAGTTCGCTGTCCGGCTCGACCCGGGCCAGATGGAAAGCACGCTTTTGAACCTGTGCCTGAATGCTTCCC
AAGCAATCGAAGGAGAAGGGAATATATGGGTTCGGGTCGTGCCTTCCGGTTCGGATATGGTGTCGATCGAAGTGCAGGAT
GACGGCCGCGGCATGCCGGCCGAGGTTTTGGCCAGGGCGATGGAGCCGTTTTACTCGGCGCGTCCGGATGGCACCGGAAC
CGGGCTGGGTCTGGCCATGATCTTTGGTTTTATCCGTCAGTCCGGTGGCGACATCAAAATCCACTCGCAGCACGGGCATG
GAACCACGGTGCGGTTGCTGATCCCGTTATGGCAGTCCACGGATTGCTCCGAGGTTATGAAGCCTGCCGGCCGCATTCTG
CTTATAGAGGATAATATGCAGGACCTGGCCCATGCCCGTCGTTTGCTGGGGGATGCTGAATTGATCGAGGCAAAAAGCGC
CGAAGAAGCAGAGAATCTGCTGCGCGACGCCTCTCCTTTCGATTACGTCCTGACCGATCTGCATCTCGGCAATGATATAG
CCGGATGGCGGATGGCCGGTGAAGCCCTGCGGCACAGCCCGGATACGGTTATCGCCGTCGTCTCGGGTCATATGCCCGAG
AACATGCCCGAAGCGCTGGCGCAGTCGGGACGGGTTGTATCTGTCGCCAAACCCCTGGATCATGCCGCACTTGCCCGATT
AACCGAGTTGAAAAGCACGGAATGA

Upstream 100 bases:

>100_bases
TGCTGATCCTGCGGTTGCGGCGCAAGATCGAGCAGGTGCCCTCCAAGCCCGTCCATTTGCAGACCCGGCGCGGACAAGGC
TATATCTTCGTTGAGACATC

Downstream 100 bases:

>100_bases
ATGGTCCTGAAGCTTTGATTCCCGGTTGAGAGGGCGCGCTGGCGCTGACGGTCTGCGTCCGCTATTTTCCCTGGTCGTCC
GTTTGATCGAGGGGATAAAG

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 834; Mature: 833

Protein sequence:

>834_residues
MTALRVPNRLGSHVSVRLRLWLALAALALATLVVGGASWATLRQTSTRLDRLHDQSLARVDDALTLSRKATAVAARAPFL
LTIESPFRLQVEAGISKTLLADIRRHLDGQNALFDKLLTEMGGSIDELTTLSLHRIELTDRILRLNAVLAIEERRFAALA
REKQKPLGQREQWLTMQRISAVLLGAGRSENLIGIGEFHRNYRALIVELEEDEKPLIQSQLLKLQEIASGRDGLFELRRA
EIGRRIRAEAAMNRIRHSTEVINNHAAEITATAQANIITERERTISAIAFASGIIVIAVVLSILMAVMAAAFVSGHVTAN
LRAISDAMMRLAVGDRSIRLPRGEHAGYEIGKLFHAFRAFRANTLRLDRSNRQLAQKNALFENLYNDMSDGLAILSNDEK
IIAHNNRLPKLLSLRATTVRTRTSLAQLLEAGNWTRWDRSEGFADLHHPSGTVVELRQSPLSTGGAVALLSDVSERRQLE
EHLQSVRRIEGLGRIAGEVAHDFGNILSTVSTNLHLLENATPERAAHLHHTLANALDLGTSLTQRLLAFARRQRLDPEIM
NLNELVTGIEDLIALALDDRISLHIFPASEQFAVRLDPGQMESTLLNLCLNASQAIEGEGNIWVRVVPSGSDMVSIEVQD
DGRGMPAEVLARAMEPFYSARPDGTGTGLGLAMIFGFIRQSGGDIKIHSQHGHGTTVRLLIPLWQSTDCSEVMKPAGRIL
LIEDNMQDLAHARRLLGDAELIEAKSAEEAENLLRDASPFDYVLTDLHLGNDIAGWRMAGEALRHSPDTVIAVVSGHMPE
NMPEALAQSGRVVSVAKPLDHAALARLTELKSTE

Sequences:

>Translated_834_residues
MTALRVPNRLGSHVSVRLRLWLALAALALATLVVGGASWATLRQTSTRLDRLHDQSLARVDDALTLSRKATAVAARAPFL
LTIESPFRLQVEAGISKTLLADIRRHLDGQNALFDKLLTEMGGSIDELTTLSLHRIELTDRILRLNAVLAIEERRFAALA
REKQKPLGQREQWLTMQRISAVLLGAGRSENLIGIGEFHRNYRALIVELEEDEKPLIQSQLLKLQEIASGRDGLFELRRA
EIGRRIRAEAAMNRIRHSTEVINNHAAEITATAQANIITERERTISAIAFASGIIVIAVVLSILMAVMAAAFVSGHVTAN
LRAISDAMMRLAVGDRSIRLPRGEHAGYEIGKLFHAFRAFRANTLRLDRSNRQLAQKNALFENLYNDMSDGLAILSNDEK
IIAHNNRLPKLLSLRATTVRTRTSLAQLLEAGNWTRWDRSEGFADLHHPSGTVVELRQSPLSTGGAVALLSDVSERRQLE
EHLQSVRRIEGLGRIAGEVAHDFGNILSTVSTNLHLLENATPERAAHLHHTLANALDLGTSLTQRLLAFARRQRLDPEIM
NLNELVTGIEDLIALALDDRISLHIFPASEQFAVRLDPGQMESTLLNLCLNASQAIEGEGNIWVRVVPSGSDMVSIEVQD
DGRGMPAEVLARAMEPFYSARPDGTGTGLGLAMIFGFIRQSGGDIKIHSQHGHGTTVRLLIPLWQSTDCSEVMKPAGRIL
LIEDNMQDLAHARRLLGDAELIEAKSAEEAENLLRDASPFDYVLTDLHLGNDIAGWRMAGEALRHSPDTVIAVVSGHMPE
NMPEALAQSGRVVSVAKPLDHAALARLTELKSTE
>Mature_833_residues
TALRVPNRLGSHVSVRLRLWLALAALALATLVVGGASWATLRQTSTRLDRLHDQSLARVDDALTLSRKATAVAARAPFLL
TIESPFRLQVEAGISKTLLADIRRHLDGQNALFDKLLTEMGGSIDELTTLSLHRIELTDRILRLNAVLAIEERRFAALAR
EKQKPLGQREQWLTMQRISAVLLGAGRSENLIGIGEFHRNYRALIVELEEDEKPLIQSQLLKLQEIASGRDGLFELRRAE
IGRRIRAEAAMNRIRHSTEVINNHAAEITATAQANIITERERTISAIAFASGIIVIAVVLSILMAVMAAAFVSGHVTANL
RAISDAMMRLAVGDRSIRLPRGEHAGYEIGKLFHAFRAFRANTLRLDRSNRQLAQKNALFENLYNDMSDGLAILSNDEKI
IAHNNRLPKLLSLRATTVRTRTSLAQLLEAGNWTRWDRSEGFADLHHPSGTVVELRQSPLSTGGAVALLSDVSERRQLEE
HLQSVRRIEGLGRIAGEVAHDFGNILSTVSTNLHLLENATPERAAHLHHTLANALDLGTSLTQRLLAFARRQRLDPEIMN
LNELVTGIEDLIALALDDRISLHIFPASEQFAVRLDPGQMESTLLNLCLNASQAIEGEGNIWVRVVPSGSDMVSIEVQDD
GRGMPAEVLARAMEPFYSARPDGTGTGLGLAMIFGFIRQSGGDIKIHSQHGHGTTVRLLIPLWQSTDCSEVMKPAGRILL
IEDNMQDLAHARRLLGDAELIEAKSAEEAENLLRDASPFDYVLTDLHLGNDIAGWRMAGEALRHSPDTVIAVVSGHMPEN
MPEALAQSGRVVSVAKPLDHAALARLTELKSTE

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=30.3030303030303, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=465, Percent_Identity=23.6559139784946, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87081816, Length=210, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91723; Mature: 91591

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALRVPNRLGSHVSVRLRLWLALAALALATLVVGGASWATLRQTSTRLDRLHDQSLARV
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DDALTLSRKATAVAARAPFLLTIESPFRLQVEAGISKTLLADIRRHLDGQNALFDKLLTE
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHH
MGGSIDELTTLSLHRIELTDRILRLNAVLAIEERRFAALAREKQKPLGQREQWLTMQRIS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AVLLGAGRSENLIGIGEFHRNYRALIVELEEDEKPLIQSQLLKLQEIASGRDGLFELRRA
HHHHCCCCCCCEEEHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
EIGRRIRAEAAMNRIRHSTEVINNHAAEITATAQANIITERERTISAIAFASGIIVIAVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCEEHHHHHHHHHHHHHHHHHHHHHH
LSILMAVMAAAFVSGHVTANLRAISDAMMRLAVGDRSIRLPRGEHAGYEIGKLFHAFRAF
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHH
RANTLRLDRSNRQLAQKNALFENLYNDMSDGLAILSNDEKIIAHNNRLPKLLSLRATTVR
HCCCEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHH
TRTSLAQLLEAGNWTRWDRSEGFADLHHPSGTVVELRQSPLSTGGAVALLSDVSERRQLE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
EHLQSVRRIEGLGRIAGEVAHDFGNILSTVSTNLHLLENATPERAAHLHHTLANALDLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHH
SLTQRLLAFARRQRLDPEIMNLNELVTGIEDLIALALDDRISLHIFPASEQFAVRLDPGQ
HHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCH
MESTLLNLCLNASQAIEGEGNIWVRVVPSGSDMVSIEVQDDGRGMPAEVLARAMEPFYSA
HHHHHHHHHHCCHHCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCC
RPDGTGTGLGLAMIFGFIRQSGGDIKIHSQHGHGTTVRLLIPLWQSTDCSEVMKPAGRIL
CCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHCCCCCEE
LIEDNMQDLAHARRLLGDAELIEAKSAEEAENLLRDASPFDYVLTDLHLGNDIAGWRMAG
EEECCHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
EALRHSPDTVIAVVSGHMPENMPEALAQSGRVVSVAKPLDHAALARLTELKSTE
HHHHCCCCEEEEEEECCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TALRVPNRLGSHVSVRLRLWLALAALALATLVVGGASWATLRQTSTRLDRLHDQSLARV
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DDALTLSRKATAVAARAPFLLTIESPFRLQVEAGISKTLLADIRRHLDGQNALFDKLLTE
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHH
MGGSIDELTTLSLHRIELTDRILRLNAVLAIEERRFAALAREKQKPLGQREQWLTMQRIS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AVLLGAGRSENLIGIGEFHRNYRALIVELEEDEKPLIQSQLLKLQEIASGRDGLFELRRA
HHHHCCCCCCCEEEHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
EIGRRIRAEAAMNRIRHSTEVINNHAAEITATAQANIITERERTISAIAFASGIIVIAVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCEEHHHHHHHHHHHHHHHHHHHHHH
LSILMAVMAAAFVSGHVTANLRAISDAMMRLAVGDRSIRLPRGEHAGYEIGKLFHAFRAF
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHH
RANTLRLDRSNRQLAQKNALFENLYNDMSDGLAILSNDEKIIAHNNRLPKLLSLRATTVR
HCCCEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHH
TRTSLAQLLEAGNWTRWDRSEGFADLHHPSGTVVELRQSPLSTGGAVALLSDVSERRQLE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
EHLQSVRRIEGLGRIAGEVAHDFGNILSTVSTNLHLLENATPERAAHLHHTLANALDLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHH
SLTQRLLAFARRQRLDPEIMNLNELVTGIEDLIALALDDRISLHIFPASEQFAVRLDPGQ
HHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCH
MESTLLNLCLNASQAIEGEGNIWVRVVPSGSDMVSIEVQDDGRGMPAEVLARAMEPFYSA
HHHHHHHHHHCCHHCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCC
RPDGTGTGLGLAMIFGFIRQSGGDIKIHSQHGHGTTVRLLIPLWQSTDCSEVMKPAGRIL
CCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHCCCCCEE
LIEDNMQDLAHARRLLGDAELIEAKSAEEAENLLRDASPFDYVLTDLHLGNDIAGWRMAG
EEECCHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
EALRHSPDTVIAVVSGHMPENMPEALAQSGRVVSVAKPLDHAALARLTELKSTE
HHHHCCCCEEEEEEECCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA