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The map label for this gene is cynT [H]

Identifier: 150398377

GI number: 150398377

Start: 3350301

End: 3350948

Strand: Reverse

Name: cynT [H]

Synonym: Smed_3185

Alternate gene names: 150398377

Gene position: 3350948-3350301 (Counterclockwise)

Preceding gene: 150398378

Following gene: 150398372

Centisome position: 88.6

GC content: 60.49

Gene sequence:

>648_bases
ATGGATATACAGGGCTTTCCGGAACATCTTCTGACCGGCTACCGCAACTTCATGAGCGGCCGCTTCAACGAACAGCAGCA
GCGTTACAAGACGCTTGCCGAGAGCGGCCAGAAACCAAGGACGATGGTTATCGCCTGTTGCGATTCCCGTGCGGCACCCG
AAACGATATTCGATGCCGGCCCGGGAGAACTCTTCGTCGTGCGCAACGTCGCCAACATGATGCCGCCATACGAACCGGAC
GGGCATTATCATTCGACTTCGGCCGCGCTCGAATTCGCAGTCCAGTCGCTGCGCGTCACCAATATCGTCGTCATGGGGCA
CGGGCGCTGCGGCGGCATCAAGGCGGCACTCGACCCGGATGCGGAGCCCCTCTCCCCCGGCGATTTCATCGGCCGCTGGA
TGAACCTGCTGAAGCCCGCCGCCGAACAGATCCAGAGCAACGAGCTCATGACCCAGGCTGAACGCCAGCGCGCTCTCGAG
CGGGTTTCGATCCGCAATTCGATCGCCAATCTCAGGACATTCCCCTGCGTCAACATTCTCGAGTCGAAAGGAAAACTGCG
CCTGCACGGCGCGTGGTTCGATATTTCGACCGGCGAGCTCTGGGTTATGGATGCCAAAACCGGGGATTTCTCCCGGCCCG
GATCGTGA

Upstream 100 bases:

>100_bases
TCTCTCAGGCATGCTATCCGCAAGTTTCCTCGAATTCCGATGAGAGACACGAGCACCACGGAAGATGCAGCATGAACGAG
TGGATGACACGGGGTTACCG

Downstream 100 bases:

>100_bases
AGACGGCGGGCCCAACGCAATCAGAGTTTCTCCGCCGGCCGGCGGAGAAAGAGCAAAAGAGCGACACGTCCTTTCGTGTC
TTCGCGATTTCTGTCGGGGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MDIQGFPEHLLTGYRNFMSGRFNEQQQRYKTLAESGQKPRTMVIACCDSRAAPETIFDAGPGELFVVRNVANMMPPYEPD
GHYHSTSAALEFAVQSLRVTNIVVMGHGRCGGIKAALDPDAEPLSPGDFIGRWMNLLKPAAEQIQSNELMTQAERQRALE
RVSIRNSIANLRTFPCVNILESKGKLRLHGAWFDISTGELWVMDAKTGDFSRPGS

Sequences:

>Translated_215_residues
MDIQGFPEHLLTGYRNFMSGRFNEQQQRYKTLAESGQKPRTMVIACCDSRAAPETIFDAGPGELFVVRNVANMMPPYEPD
GHYHSTSAALEFAVQSLRVTNIVVMGHGRCGGIKAALDPDAEPLSPGDFIGRWMNLLKPAAEQIQSNELMTQAERQRALE
RVSIRNSIANLRTFPCVNILESKGKLRLHGAWFDISTGELWVMDAKTGDFSRPGS
>Mature_215_residues
MDIQGFPEHLLTGYRNFMSGRFNEQQQRYKTLAESGQKPRTMVIACCDSRAAPETIFDAGPGELFVVRNVANMMPPYEPD
GHYHSTSAALEFAVQSLRVTNIVVMGHGRCGGIKAALDPDAEPLSPGDFIGRWMNLLKPAAEQIQSNELMTQAERQRALE
RVSIRNSIANLRTFPCVNILESKGKLRLHGAWFDISTGELWVMDAKTGDFSRPGS

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=205, Percent_Identity=32.1951219512195, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786318, Length=181, Percent_Identity=29.2817679558011, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115532990, Length=239, Percent_Identity=24.6861924686192, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=176, Percent_Identity=27.8409090909091, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23887; Mature: 23887

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQGFPEHLLTGYRNFMSGRFNEQQQRYKTLAESGQKPRTMVIACCDSRAAPETIFDAG
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCCC
PGELFVVRNVANMMPPYEPDGHYHSTSAALEFAVQSLRVTNIVVMGHGRCGGIKAALDPD
CCCEEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCC
AEPLSPGDFIGRWMNLLKPAAEQIQSNELMTQAERQRALERVSIRNSIANLRTFPCVNIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ESKGKLRLHGAWFDISTGELWVMDAKTGDFSRPGS
HCCCCEEEEEEEEEECCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDIQGFPEHLLTGYRNFMSGRFNEQQQRYKTLAESGQKPRTMVIACCDSRAAPETIFDAG
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCCC
PGELFVVRNVANMMPPYEPDGHYHSTSAALEFAVQSLRVTNIVVMGHGRCGGIKAALDPD
CCCEEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCC
AEPLSPGDFIGRWMNLLKPAAEQIQSNELMTQAERQRALERVSIRNSIANLRTFPCVNIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ESKGKLRLHGAWFDISTGELWVMDAKTGDFSRPGS
HCCCCEEEEEEEEEECCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]