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The map label for this gene is pdxY [H]

Identifier: 150398378

GI number: 150398378

Start: 3351145

End: 3352026

Strand: Reverse

Name: pdxY [H]

Synonym: Smed_3186

Alternate gene names: 150398378

Gene position: 3352026-3351145 (Counterclockwise)

Preceding gene: 150398381

Following gene: 150398377

Centisome position: 88.63

GC content: 66.1

Gene sequence:

>882_bases
ATGTCCGAATCGCCTGCCGCGCCCGGTGCCATCATCGTGATTTCCAGCCATGTGGTGCGGGGCGCAGTCGGCAACCGGGC
GGCCGTCTTCGCTCTGGAAACGCTTGGGCACCGGGTCTGGGCATTGCCGACGGTCATTCTCCCCTGGCATCCCGGGCACG
GCCCGTCGACGCGGGTGATCATGCCGGACGCGGACTTCCGGTCGATCATCGACGATCTCATCCGTGCACCCTGGATCGGA
GAGGTGCGCGCGGTTCTTTCCGGTTATATGGGATCCCCGGCGCAGGCGGCGGGCGTCGCTCGACTCGTGGCGGCGCTGCG
CGAACGTAATCCCGACCTCTTCTATGCCTGTGATCCGATCATCGGCGATGCGGGCGGCCTTTACGTCCCGGTAGAGATCG
CCACCGCCATTCGCGAACTGCTAATGCCGCTTGCGACGCTCGCCACACCCAACCGGTTCGAACTTTCCTGGTTGGCAGGC
GCCGCCCTCGAGACGAATGCAGACCTCCTCGAGGCGGCGGTCGATCTCGGTCCTTCGCGCGTACTCGTGACGTCTGCGAT
CCCGATGATGAGCGGCGGCACGGGCAATCTCTACCTCTCCGGGCGGCATGCCCTGCTCGCCGAGCACCGGCTGATCGACA
GCCCGCCGAACGGCACCGGCGACCTGCTCTCCGCCGTATTCCTGGCGCGACTGCTCGAAGGGCTTCCGGAGGAGCGCGCG
CTGCAGATGGCGACCGCAAGCGTCTATGAGATCATCGCGCGAAGCCGCAAACGGGATGCCGATGAGTTGACGCTCGAGCA
GGATGCTTCGAGCCTGGCGACGCCGATGGCGATGGTCCAGATGCGCCGCCTCCTGCATCCGAGCCAAGCGCGGAAGAAAT
AG

Upstream 100 bases:

>100_bases
AATCGCCGAAGCTTATGTCACCGGCACTCTTCGGGAGAGCCCGTTGACAGGCCGTGAGGGCCGGGCGATCACAATTCAGA
ACGGAAAAAAGGGGCCTCCA

Downstream 100 bases:

>100_bases
CGGTCGACACGGAAGAATTGCCTTCTGGTCGCATTTCGTCCTTCCCGCTGGGCCAAGCTCGCTGTAACAGTTCGACGCTT
CATGCTTCCCTGACCGTCTC

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSESPAAPGAIIVISSHVVRGAVGNRAAVFALETLGHRVWALPTVILPWHPGHGPSTRVIMPDADFRSIIDDLIRAPWIG
EVRAVLSGYMGSPAQAAGVARLVAALRERNPDLFYACDPIIGDAGGLYVPVEIATAIRELLMPLATLATPNRFELSWLAG
AALETNADLLEAAVDLGPSRVLVTSAIPMMSGGTGNLYLSGRHALLAEHRLIDSPPNGTGDLLSAVFLARLLEGLPEERA
LQMATASVYEIIARSRKRDADELTLEQDASSLATPMAMVQMRRLLHPSQARKK

Sequences:

>Translated_293_residues
MSESPAAPGAIIVISSHVVRGAVGNRAAVFALETLGHRVWALPTVILPWHPGHGPSTRVIMPDADFRSIIDDLIRAPWIG
EVRAVLSGYMGSPAQAAGVARLVAALRERNPDLFYACDPIIGDAGGLYVPVEIATAIRELLMPLATLATPNRFELSWLAG
AALETNADLLEAAVDLGPSRVLVTSAIPMMSGGTGNLYLSGRHALLAEHRLIDSPPNGTGDLLSAVFLARLLEGLPEERA
LQMATASVYEIIARSRKRDADELTLEQDASSLATPMAMVQMRRLLHPSQARKK
>Mature_292_residues
SESPAAPGAIIVISSHVVRGAVGNRAAVFALETLGHRVWALPTVILPWHPGHGPSTRVIMPDADFRSIIDDLIRAPWIGE
VRAVLSGYMGSPAQAAGVARLVAALRERNPDLFYACDPIIGDAGGLYVPVEIATAIRELLMPLATLATPNRFELSWLAGA
ALETNADLLEAAVDLGPSRVLVTSAIPMMSGGTGNLYLSGRHALLAEHRLIDSPPNGTGDLLSAVFLARLLEGLPEERAL
QMATASVYEIIARSRKRDADELTLEQDASSLATPMAMVQMRRLLHPSQARKK

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=238, Percent_Identity=30.672268907563, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1788758, Length=272, Percent_Identity=31.9852941176471, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787924, Length=278, Percent_Identity=31.294964028777, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17507759, Length=287, Percent_Identity=29.2682926829268, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17507757, Length=297, Percent_Identity=28.956228956229, Blast_Score=104, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=236, Percent_Identity=30.5084745762712, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=309, Percent_Identity=27.5080906148867, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45553007, Length=296, Percent_Identity=29.0540540540541, Blast_Score=118, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31283; Mature: 31151

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESPAAPGAIIVISSHVVRGAVGNRAAVFALETLGHRVWALPTVILPWHPGHGPSTRVI
CCCCCCCCCEEEEEECHHHHCCCCCCHHHHHHHHHCCHHHHCCEEEEECCCCCCCCCEEE
MPDADFRSIIDDLIRAPWIGEVRAVLSGYMGSPAQAAGVARLVAALRERNPDLFYACDPI
ECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCC
IGDAGGLYVPVEIATAIRELLMPLATLATPNRFELSWLAGAALETNADLLEAAVDLGPSR
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCHHCCCHHHHHHHHHCCCCE
VLVTSAIPMMSGGTGNLYLSGRHALLAEHRLIDSPPNGTGDLLSAVFLARLLEGLPEERA
EEEEHHCHHCCCCCCCEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
LQMATASVYEIIARSRKRDADELTLEQDASSLATPMAMVQMRRLLHPSQARKK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
SESPAAPGAIIVISSHVVRGAVGNRAAVFALETLGHRVWALPTVILPWHPGHGPSTRVI
CCCCCCCCEEEEEECHHHHCCCCCCHHHHHHHHHCCHHHHCCEEEEECCCCCCCCCEEE
MPDADFRSIIDDLIRAPWIGEVRAVLSGYMGSPAQAAGVARLVAALRERNPDLFYACDPI
ECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCC
IGDAGGLYVPVEIATAIRELLMPLATLATPNRFELSWLAGAALETNADLLEAAVDLGPSR
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCHHCCCHHHHHHHHHCCCCE
VLVTSAIPMMSGGTGNLYLSGRHALLAEHRLIDSPPNGTGDLLSAVFLARLLEGLPEERA
EEEEHHCHHCCCCCCCEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
LQMATASVYEIIARSRKRDADELTLEQDASSLATPMAMVQMRRLLHPSQARKK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]