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The map label for this gene is asd [H]

Identifier: 150398374

GI number: 150398374

Start: 3347683

End: 3348717

Strand: Direct

Name: asd [H]

Synonym: Smed_3182

Alternate gene names: 150398374

Gene position: 3347683-3348717 (Clockwise)

Preceding gene: 150398373

Following gene: 150398375

Centisome position: 88.52

GC content: 58.84

Gene sequence:

>1035_bases
ATGGGTTTCAAAATTGCTGTCGCAGGCGCCACCGGCAATGTCGGCCGGGAGATGCTGAACATTCTTTCCGAGCGCGGTTT
CCCGGCGGATGAAGTGGTGGCGCTCGCCTCCTCGCGTTCGGTCGGCACCGAGGTTTCTTACGGCGACAAGACGCTGAGAG
TCACGAATCTCGACACCTATGATTTTTCCGATACTGATATCTGCCTGATGTCGGCCGGCGGCGCCGTCTCGCAGAAATAC
TCGCCGAAGATCGGTCGGGAGGGCTGCGTCGTTATCGATAATTCCTCGGCCTGGCGCTATGACTCCGAGGTTCCGTTGAT
CGTGCCGGAGGTGAACGCGGATGCAATCTCGATGTTCTCCAAGAAGAACATCATCGCCAATCCGAATTGTTCGACGGCAC
AGCTCGTCGTCGCGCTGAAGCCGCTGCACGACCGCGCCAAGATCAAGCGCGTCGTCGTTTCCACCTATCAATCGGTTTCC
GGCGCCGGCAAGGACGGCATGGACGAGCTCTTCAATCAGACGCGCGCCGTCTTCGTCGCCGATCCGATCGAGAGCAAGAA
ATTCACCAAGCGTATCGCCTTCAACGTCATCCCGCACATCGACGTTTTCATGGAGGATGGCTATACCAAGGAAGAATGGA
AGGTTCTGGCCGAGACCAAGAAGATGCTCGACCCGAAGATCAAGGTGACCTGCACGGCCGTGCGCGTACCGGTCTTCATC
GGCCATTCCGAATCGGTCAATATCGAATTCGAGAACGAGATCACTGCCGATGAAGCGCGCGAGATCCTGCGTGAAGCACC
GGGTTGCCTCGTCGTCGACAAGCATGAGAACGGCGGCTATGTGACGCCTTACGAATGCGCCGGCGAGGACGCAACCTATA
TCTCGCGCATCCGCGAGGATGCGACCGTCGAAAACGGCCTGAACATATGGATCGTCTCCGACAACCTGCGCAAGGGCGCG
GCGCTCAACGCGGTGCAGATCGCCGAGCTCCTGGTGAACCGTGGCCTGATCAAGCCGCGCAAGCAGGCGGCTTGA

Upstream 100 bases:

>100_bases
CCGCTCTCTCCCCGGTACGGCCGGGGACAGGAACTTCGCGGTCGGACCGCGCGGTTTCACCCTCCACCCGATGAGGAGAG
ACAGAAAGAGAGCTTAGATC

Downstream 100 bases:

>100_bases
CCGGCTTCGGCTGGCCTCGATTCTTAGCCCCGCCTTTCTCGCTACGGCGACAGGCGGGGTTTCGCAGTTCTTTCGGCAGG
CGACGGATTCACGTGAAACC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGFKIAVAGATGNVGREMLNILSERGFPADEVVALASSRSVGTEVSYGDKTLRVTNLDTYDFSDTDICLMSAGGAVSQKY
SPKIGREGCVVIDNSSAWRYDSEVPLIVPEVNADAISMFSKKNIIANPNCSTAQLVVALKPLHDRAKIKRVVVSTYQSVS
GAGKDGMDELFNQTRAVFVADPIESKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
GHSESVNIEFENEITADEAREILREAPGCLVVDKHENGGYVTPYECAGEDATYISRIREDATVENGLNIWIVSDNLRKGA
ALNAVQIAELLVNRGLIKPRKQAA

Sequences:

>Translated_344_residues
MGFKIAVAGATGNVGREMLNILSERGFPADEVVALASSRSVGTEVSYGDKTLRVTNLDTYDFSDTDICLMSAGGAVSQKY
SPKIGREGCVVIDNSSAWRYDSEVPLIVPEVNADAISMFSKKNIIANPNCSTAQLVVALKPLHDRAKIKRVVVSTYQSVS
GAGKDGMDELFNQTRAVFVADPIESKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
GHSESVNIEFENEITADEAREILREAPGCLVVDKHENGGYVTPYECAGEDATYISRIREDATVENGLNIWIVSDNLRKGA
ALNAVQIAELLVNRGLIKPRKQAA
>Mature_343_residues
GFKIAVAGATGNVGREMLNILSERGFPADEVVALASSRSVGTEVSYGDKTLRVTNLDTYDFSDTDICLMSAGGAVSQKYS
PKIGREGCVVIDNSSAWRYDSEVPLIVPEVNADAISMFSKKNIIANPNCSTAQLVVALKPLHDRAKIKRVVVSTYQSVSG
AGKDGMDELFNQTRAVFVADPIESKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFIG
HSESVNIEFENEITADEAREILREAPGCLVVDKHENGGYVTPYECAGEDATYISRIREDATVENGLNIWIVSDNLRKGAA
LNAVQIAELLVNRGLIKPRKQAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=33.8278931750742, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1789841, Length=353, Percent_Identity=27.1954674220963, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=398, Percent_Identity=28.894472361809, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37623; Mature: 37492

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKIAVAGATGNVGREMLNILSERGFPADEVVALASSRSVGTEVSYGDKTLRVTNLDTY
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCEEECCCCEEEEEECCCC
DFSDTDICLMSAGGAVSQKYSPKIGREGCVVIDNSSAWRYDSEVPLIVPEVNADAISMFS
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCEEEECCCCHHHHHHH
KKNIIANPNCSTAQLVVALKPLHDRAKIKRVVVSTYQSVSGAGKDGMDELFNQTRAVFVA
CCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEE
DPIESKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSESVNIEFENEITADEAREILREAPGCLVVDKHENGGYVTPYECAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCEECCHHCCCCCHHHHHHHHHC
ATVENGLNIWIVSDNLRKGAALNAVQIAELLVNRGLIKPRKQAA
CHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHCC
>Mature Secondary Structure 
GFKIAVAGATGNVGREMLNILSERGFPADEVVALASSRSVGTEVSYGDKTLRVTNLDTY
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCEEECCCCEEEEEECCCC
DFSDTDICLMSAGGAVSQKYSPKIGREGCVVIDNSSAWRYDSEVPLIVPEVNADAISMFS
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCEEEECCCCHHHHHHH
KKNIIANPNCSTAQLVVALKPLHDRAKIKRVVVSTYQSVSGAGKDGMDELFNQTRAVFVA
CCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEE
DPIESKKFTKRIAFNVIPHIDVFMEDGYTKEEWKVLAETKKMLDPKIKVTCTAVRVPVFI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSESVNIEFENEITADEAREILREAPGCLVVDKHENGGYVTPYECAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCEECCHHCCCCCHHHHHHHHHC
ATVENGLNIWIVSDNLRKGAALNAVQIAELLVNRGLIKPRKQAA
CHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]