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The map label for this gene is ttuD [H]

Identifier: 150398355

GI number: 150398355

Start: 3323368

End: 3324639

Strand: Reverse

Name: ttuD [H]

Synonym: Smed_3163

Alternate gene names: 150398355

Gene position: 3324639-3323368 (Counterclockwise)

Preceding gene: 150398356

Following gene: 150398353

Centisome position: 87.91

GC content: 68.16

Gene sequence:

>1272_bases
ATGGCCTCGATCGAACCGCGTCCCTTCCTCATCTCCCTCTTCGAGGCGGCCGTTCTCGCGGCCGATCCTTACGCCGCGAT
CCGGGCGCATCTGCCGGCGCGGCCGAAAGGGCGGACGATCGTGGTCGGTGCCGGCAAGGCCGCAAGCCAGATGGCCGCCG
CTTTCGAGCGGCTCTGGGAAGGGCCGCTTGACGGAGCCGTCGTGGCCCGCCACGGACCGATTGAAAAATGCGAACGGATC
AAGGTCTTTCAGTCTGCCCATCCGGTGCCGGATGAGGCGGGGCTCGCGGCTTCGTCCGCACTCCTCGAAATGGTCGAGGG
GTTGACTTCAGACGATCTCGTCGTCGCGCTCATCTCCGGCGGCGGCTCGGCCCTGCTTCCGGCGCCGCCCGGCGGCTTGA
CACTGGAGGACGAGATTGCCGTCAACAGGGCTCTCCTTGCCTCGGGCGCGCCGATCTCGGCCATGAATGTGGTGCGCAAG
CACGTCTCGCGTGTCAAAGGCGGCCGGCTTGCGCTTGCCGCTGCGCCGGCGCGGGTCGTCAGCCTCGTCGTCTCCGACGT
TCCGGGAGATAATCCCGCCTTCGTCGCCTCCGGCCCGACTGTGCCGGACCGCTCGAGCCTCGAAGAGGCGCGCGAAATCG
TCGCCCGCTACGCAATGGCCCTGCCCGAGCGGGTGGCGGCGCATCTCTCCGCCGATGCCGCACGGGCGCCGAGCCCGGAC
GATCCTGTGTTCGCCCGCAACGAGGTCCATGTCATCGCTTCGGCGCGTGTTTCACTGGAAGCGGCGGCGGCAAGGGCGCG
GGAAAGCGGCATCGAGGCGGCGATCCTCTCGGACGCGATCGAGGGCGAGGCGCGCGACATCGGCCGTATGCATGCGGCGC
TGGCGCGCGAAGTGGCCTTGCATAACCATCCGTTTGCCAGGCCCGTGGTGCTGCTTTCCGGCGGCGAAACGACCGTGACG
ATCTCCGGCAAGGATTACGGCAGGGGCGGGCGCAACAGCGAGTTTCTCCTGTCGCTGGCGCTCGACATCGACGGCGCCGA
TGGCATCGATGCGCTTGCTGCCGATACGGATGGCATCGACGGGTCCGAGGACAATGCCGGTGCCTTCGCCGACGGGGCGA
GCATCGCTCGGATGCGGGGTGCCGGCGTGGATCCCCGCCTGCACCTTACCCGCCACGATGCCTGGACCGCCTTCAAGGCA
AGCGGCGACCTCTTCGTACCAGGCCCGACCGGGACAAACGTCAATGATCTGCGGGCAGTGTTGATCCGCTGA

Upstream 100 bases:

>100_bases
GCACCGCAACAGTCTGACGCCTCGAAAGATCATTGCGACGGAAGCGTTCAGCCTGCATGGTGGCGCTTCGTCTCCCCAAC
ACGAAATCCCGGACTGTTTC

Downstream 100 bases:

>100_bases
GTTTGCTTCCTCGAGAGAGGATGGCGTGTCGGGCGGGGGTTGCCCCTCCCACTGGACTGGTGGGAGGGCAGCCTGACAGC
ACTGGCTCGCTATTTCACCC

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MASIEPRPFLISLFEAAVLAADPYAAIRAHLPARPKGRTIVVGAGKAASQMAAAFERLWEGPLDGAVVARHGPIEKCERI
KVFQSAHPVPDEAGLAASSALLEMVEGLTSDDLVVALISGGGSALLPAPPGGLTLEDEIAVNRALLASGAPISAMNVVRK
HVSRVKGGRLALAAAPARVVSLVVSDVPGDNPAFVASGPTVPDRSSLEEAREIVARYAMALPERVAAHLSADAARAPSPD
DPVFARNEVHVIASARVSLEAAAARARESGIEAAILSDAIEGEARDIGRMHAALAREVALHNHPFARPVVLLSGGETTVT
ISGKDYGRGGRNSEFLLSLALDIDGADGIDALAADTDGIDGSEDNAGAFADGASIARMRGAGVDPRLHLTRHDAWTAFKA
SGDLFVPGPTGTNVNDLRAVLIR

Sequences:

>Translated_423_residues
MASIEPRPFLISLFEAAVLAADPYAAIRAHLPARPKGRTIVVGAGKAASQMAAAFERLWEGPLDGAVVARHGPIEKCERI
KVFQSAHPVPDEAGLAASSALLEMVEGLTSDDLVVALISGGGSALLPAPPGGLTLEDEIAVNRALLASGAPISAMNVVRK
HVSRVKGGRLALAAAPARVVSLVVSDVPGDNPAFVASGPTVPDRSSLEEAREIVARYAMALPERVAAHLSADAARAPSPD
DPVFARNEVHVIASARVSLEAAAARARESGIEAAILSDAIEGEARDIGRMHAALAREVALHNHPFARPVVLLSGGETTVT
ISGKDYGRGGRNSEFLLSLALDIDGADGIDALAADTDGIDGSEDNAGAFADGASIARMRGAGVDPRLHLTRHDAWTAFKA
SGDLFVPGPTGTNVNDLRAVLIR
>Mature_422_residues
ASIEPRPFLISLFEAAVLAADPYAAIRAHLPARPKGRTIVVGAGKAASQMAAAFERLWEGPLDGAVVARHGPIEKCERIK
VFQSAHPVPDEAGLAASSALLEMVEGLTSDDLVVALISGGGSALLPAPPGGLTLEDEIAVNRALLASGAPISAMNVVRKH
VSRVKGGRLALAAAPARVVSLVVSDVPGDNPAFVASGPTVPDRSSLEEAREIVARYAMALPERVAAHLSADAARAPSPDD
PVFARNEVHVIASARVSLEAAAARARESGIEAAILSDAIEGEARDIGRMHAALAREVALHNHPFARPVVLLSGGETTVTI
SGKDYGRGGRNSEFLLSLALDIDGADGIDALAADTDGIDGSEDNAGAFADGASIARMRGAGVDPRLHLTRHDAWTAFKAS
GDLFVPGPTGTNVNDLRAVLIR

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=488, Percent_Identity=34.6311475409836, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI193205461, Length=450, Percent_Identity=28.4444444444444, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19920578, Length=438, Percent_Identity=29.9086757990868, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43645; Mature: 43514

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIEPRPFLISLFEAAVLAADPYAAIRAHLPARPKGRTIVVGAGKAASQMAAAFERLWE
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
GPLDGAVVARHGPIEKCERIKVFQSAHPVPDEAGLAASSALLEMVEGLTSDDLVVALISG
CCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEC
GGSALLPAPPGGLTLEDEIAVNRALLASGAPISAMNVVRKHVSRVKGGRLALAAAPARVV
CCCEECCCCCCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHH
SLVVSDVPGDNPAFVASGPTVPDRSSLEEAREIVARYAMALPERVAAHLSADAARAPSPD
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DPVFARNEVHVIASARVSLEAAAARARESGIEAAILSDAIEGEARDIGRMHAALAREVAL
CCCEECCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HNHPFARPVVLLSGGETTVTISGKDYGRGGRNSEFLLSLALDIDGADGIDALAADTDGID
CCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHCCCCCCC
GSEDNAGAFADGASIARMRGAGVDPRLHLTRHDAWTAFKASGDLFVPGPTGTNVNDLRAV
CCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCCEEEEECCCCEEECCCCCCCHHHHHHE
LIR
ECC
>Mature Secondary Structure 
ASIEPRPFLISLFEAAVLAADPYAAIRAHLPARPKGRTIVVGAGKAASQMAAAFERLWE
CCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
GPLDGAVVARHGPIEKCERIKVFQSAHPVPDEAGLAASSALLEMVEGLTSDDLVVALISG
CCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEC
GGSALLPAPPGGLTLEDEIAVNRALLASGAPISAMNVVRKHVSRVKGGRLALAAAPARVV
CCCEECCCCCCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHH
SLVVSDVPGDNPAFVASGPTVPDRSSLEEAREIVARYAMALPERVAAHLSADAARAPSPD
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DPVFARNEVHVIASARVSLEAAAARARESGIEAAILSDAIEGEARDIGRMHAALAREVAL
CCCEECCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HNHPFARPVVLLSGGETTVTISGKDYGRGGRNSEFLLSLALDIDGADGIDALAADTDGID
CCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHCCCCCCC
GSEDNAGAFADGASIARMRGAGVDPRLHLTRHDAWTAFKASGDLFVPGPTGTNVNDLRAV
CCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCCEEEEECCCCEEECCCCCCCHHHHHHE
LIR
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]