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The map label for this gene is agaR [H]

Identifier: 150398329

GI number: 150398329

Start: 3285139

End: 3285936

Strand: Reverse

Name: agaR [H]

Synonym: Smed_3135

Alternate gene names: 150398329

Gene position: 3285936-3285139 (Counterclockwise)

Preceding gene: 150398333

Following gene: 150398328

Centisome position: 86.89

GC content: 64.54

Gene sequence:

>798_bases
GTGCACGGTTTGCTTATGACAACAGATTTGCTGCTGCGAGAAAGAAAAAGCCTGATCCAGGAAAGGCTGAGAACCGAGGG
CCGGGTGCTCGCGGTTGATCTCGCGCGCGAACTGGGCGTGTCGGAAGACACGATCCGGCGGGACCTGCGCGAGATGGCCG
CCGCTGGTCTTTGCGAGCGTGTTTATGGCGGAGCGCTGCCGATTCCGCCCGATGCAGGTCTGCTTACGGTGCGGGTGTCT
CGCGCGCCCGAACGGAAGGCGGCGCTGGCACGGGTTGCGGTCGGGTTTCTGAGGCCGCGCATGACCGTGTTCCTCGATGC
CGGTTCGGCGAATCTCGCGATCGCGCAGGCAATCGGTCCCGAACTCTCGGCGACGGTCATCACCAACACGCCCCTGATTG
CCGCGGCCTTGATGGAAAAGCCGGGCATCGACGTCATCCTCATCGGCGGTCCGTTGAACCGCGCCGTCGGCGCGGCGGTC
AGTGCACGGGCGCAGCGTGACGCCGAGCTTTTGAGGCCGGATCTTGCGATCCTCGGGACATGCGGTGCGGATGCCGAGGC
AGGCCTGACCGCGTTTCATGTCGAGGATGCGGAATTCAAGCGGCTGATCGCTTCCAGGAGCCGCTCCCTGCTTGCCGCCG
TGACGACCGAGAAGCTCGCTACCGCAGCGCCGCACACGATAGTCCCCATAGACGGTTCCTTTACGCTTGTTCTCGAAGCG
GATGCGCCGGATTCAGAGGTCGCGGCGCTCAGGGCGCGAGGTGCGAACGTCGTTCTTGCGAAGGAGATCGCCGGATGA

Upstream 100 bases:

>100_bases
GCGCGGAATGTTCCGTCGGCTTCCGCAGTTTTGCGACCGGACTGGATTGAAATACCCGATCAAGGGTGATAATCACGTTT
TCATCGATTCATGCACGTTT

Downstream 100 bases:

>100_bases
ACATTGCCCATTTCGACCTTGGGACCGAAGAAGCCGTGATCCCGACGTCAACTTCATCGAAAATCACCATTTGAGCCGGA
TCGATCCGGCAGCGGAAGGT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MHGLLMTTDLLLRERKSLIQERLRTEGRVLAVDLARELGVSEDTIRRDLREMAAAGLCERVYGGALPIPPDAGLLTVRVS
RAPERKAALARVAVGFLRPRMTVFLDAGSANLAIAQAIGPELSATVITNTPLIAAALMEKPGIDVILIGGPLNRAVGAAV
SARAQRDAELLRPDLAILGTCGADAEAGLTAFHVEDAEFKRLIASRSRSLLAAVTTEKLATAAPHTIVPIDGSFTLVLEA
DAPDSEVAALRARGANVVLAKEIAG

Sequences:

>Translated_265_residues
MHGLLMTTDLLLRERKSLIQERLRTEGRVLAVDLARELGVSEDTIRRDLREMAAAGLCERVYGGALPIPPDAGLLTVRVS
RAPERKAALARVAVGFLRPRMTVFLDAGSANLAIAQAIGPELSATVITNTPLIAAALMEKPGIDVILIGGPLNRAVGAAV
SARAQRDAELLRPDLAILGTCGADAEAGLTAFHVEDAEFKRLIASRSRSLLAAVTTEKLATAAPHTIVPIDGSFTLVLEA
DAPDSEVAALRARGANVVLAKEIAG
>Mature_265_residues
MHGLLMTTDLLLRERKSLIQERLRTEGRVLAVDLARELGVSEDTIRRDLREMAAAGLCERVYGGALPIPPDAGLLTVRVS
RAPERKAALARVAVGFLRPRMTVFLDAGSANLAIAQAIGPELSATVITNTPLIAAALMEKPGIDVILIGGPLNRAVGAAV
SARAQRDAELLRPDLAILGTCGADAEAGLTAFHVEDAEFKRLIASRSRSLLAAVTTEKLATAAPHTIVPIDGSFTLVLEA
DAPDSEVAALRARGANVVLAKEIAG

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=259, Percent_Identity=26.6409266409266, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789829, Length=233, Percent_Identity=30.4721030042918, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=26.171875, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI226510968, Length=254, Percent_Identity=27.5590551181102, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789170, Length=202, Percent_Identity=28.7128712871287, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787540, Length=180, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082344, Length=209, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788069, Length=198, Percent_Identity=25.7575757575758, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27828; Mature: 27828

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGLLMTTDLLLRERKSLIQERLRTEGRVLAVDLARELGVSEDTIRRDLREMAAAGLCER
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHH
VYGGALPIPPDAGLLTVRVSRAPERKAALARVAVGFLRPRMTVFLDAGSANLAIAQAIGP
HHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCC
ELSATVITNTPLIAAALMEKPGIDVILIGGPLNRAVGAAVSARAQRDAELLRPDLAILGT
CCEEEEEECCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
CGADAEAGLTAFHVEDAEFKRLIASRSRSLLAAVTTEKLATAAPHTIVPIDGSFTLVLEA
CCCCCCCCEEEEEECHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCEEEEECCCEEEEEEC
DAPDSEVAALRARGANVVLAKEIAG
CCCCHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MHGLLMTTDLLLRERKSLIQERLRTEGRVLAVDLARELGVSEDTIRRDLREMAAAGLCER
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHH
VYGGALPIPPDAGLLTVRVSRAPERKAALARVAVGFLRPRMTVFLDAGSANLAIAQAIGP
HHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCC
ELSATVITNTPLIAAALMEKPGIDVILIGGPLNRAVGAAVSARAQRDAELLRPDLAILGT
CCEEEEEECCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
CGADAEAGLTAFHVEDAEFKRLIASRSRSLLAAVTTEKLATAAPHTIVPIDGSFTLVLEA
CCCCCCCCEEEEEECHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCEEEEECCCEEEEEEC
DAPDSEVAALRARGANVVLAKEIAG
CCCCHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]