| Definition | Sinorhizobium medicae WSM419 chromosome, complete genome. |
|---|---|
| Accession | NC_009636 |
| Length | 3,781,904 |
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The map label for this gene is gno [H]
Identifier: 150398318
GI number: 150398318
Start: 3272642
End: 3273430
Strand: Reverse
Name: gno [H]
Synonym: Smed_3124
Alternate gene names: 150398318
Gene position: 3273430-3272642 (Counterclockwise)
Preceding gene: 150398319
Following gene: 150398315
Centisome position: 86.56
GC content: 60.84
Gene sequence:
>789_bases ATGTCTGAAATCAGTCTTGACGCACCGAAATTGTTCGATCTTGCCGGAAACGTCGCCCTCGTGACCGGCGCGGGCAGCGG CATCGGCCAACGCATCGCCATCGGTCTCGCACAGTGCGGCGCAGATGTCGGGTTACTAGACCGACGGACCGATGATGGTC TCGCGAAGACGGCCGATCTCATCGAAAAGGCTGGGCGTCGCAGCATTCAGATCGCCGCTGATGTCACCAGCGGCGCGGCG CTCGACGAGGCGGTTGCGCGCACAGAAGCGGAGCTGGGCCCGCTGACCCTCGCGCTCAACGCCGCGGGCATCGCCAATGC TCATCCGGCGGAGGAGATGGAGGAAACTCAGTTCCAGACGATGATGGACGTCAATCTGAAAGGCGTTTTCCTCTCCTGCC AGGCGGAAGCGCGCGCCATGTTGAGGAACGGACGCGGGTCGATCGTCAACATCGCCTCGATGTCCGGCGTCATCGTGAAT CGAGGACTTAACCAGTGCCACTACAACGCCTCTAAGGCGGGTGTAATTCACATGTCGAAGTCCATGGCGATGGAGTGGGT AGGCCGCGGCATCCGGGTCAACACCATCAGTCCGGGCTATACGGCAACACCTATGAATACTAGACCGGAAATGGTGCACC AGACCAGGCTCTTCGAGGAACAGACGCCGATGCAGCGCATGGCTGGCGTGGACGAAATGGTCGGCCCGGCCGTTTTCCTT CTGTCGGATGCGGCGAGCTTCGTAACCGGAGTAGACCTTCTCGTTGATGGCGGCTTCTGCTGCTGGTGA
Upstream 100 bases:
>100_bases GTCATGGCGCAGGGCAAGCAGGCCGGCATCCTGAACCGCGAGGATGCGAACGACGTCTCTGTCATGGAACTGGCAACGAT CTAAGCAGGAAAGAACCCAT
Downstream 100 bases:
>100_bases TATCGCCGGTCAGGAGGCGGCGCCGCAATCTCGCCGGTGCCGCTTCAATCTGACCTGCGATCTCACAGAATTTCGTCGAG CGCCGCGACCAGTTTGGCGC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 262; Mature: 261
Protein sequence:
>262_residues MSEISLDAPKLFDLAGNVALVTGAGSGIGQRIAIGLAQCGADVGLLDRRTDDGLAKTADLIEKAGRRSIQIAADVTSGAA LDEAVARTEAELGPLTLALNAAGIANAHPAEEMEETQFQTMMDVNLKGVFLSCQAEARAMLRNGRGSIVNIASMSGVIVN RGLNQCHYNASKAGVIHMSKSMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTRLFEEQTPMQRMAGVDEMVGPAVFL LSDAASFVTGVDLLVDGGFCCW
Sequences:
>Translated_262_residues MSEISLDAPKLFDLAGNVALVTGAGSGIGQRIAIGLAQCGADVGLLDRRTDDGLAKTADLIEKAGRRSIQIAADVTSGAA LDEAVARTEAELGPLTLALNAAGIANAHPAEEMEETQFQTMMDVNLKGVFLSCQAEARAMLRNGRGSIVNIASMSGVIVN RGLNQCHYNASKAGVIHMSKSMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTRLFEEQTPMQRMAGVDEMVGPAVFL LSDAASFVTGVDLLVDGGFCCW >Mature_261_residues SEISLDAPKLFDLAGNVALVTGAGSGIGQRIAIGLAQCGADVGLLDRRTDDGLAKTADLIEKAGRRSIQIAADVTSGAAL DEAVARTEAELGPLTLALNAAGIANAHPAEEMEETQFQTMMDVNLKGVFLSCQAEARAMLRNGRGSIVNIASMSGVIVNR GLNQCHYNASKAGVIHMSKSMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTRLFEEQTPMQRMAGVDEMVGPAVFLL SDAASFVTGVDLLVDGGFCCW
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=35.5731225296443, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=31.5589353612167, Blast_Score=114, Evalue=9e-26, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=32, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=30.0411522633745, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=31.7829457364341, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4758504, Length=227, Percent_Identity=34.3612334801762, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=30.3149606299213, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=32.4561403508772, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=28.1853281853282, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI310128830, Length=178, Percent_Identity=26.4044943820225, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI310115468, Length=178, Percent_Identity=26.4044943820225, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=28.6343612334802, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=29.7979797979798, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=27.6679841897233, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=26.3959390862944, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31542939, Length=195, Percent_Identity=30.2564102564103, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI142976729, Length=251, Percent_Identity=23.1075697211155, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI83715985, Length=228, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI226371731, Length=203, Percent_Identity=26.1083743842365, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=26.4, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=35.4330708661417, Blast_Score=137, Evalue=5e-34, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=36.3636363636364, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=34.6774193548387, Blast_Score=127, Evalue=5e-31, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=33.9920948616601, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=30.6513409961686, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=32.5490196078431, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.2040816326531, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.4677419354839, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=31.640625, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=31.5573770491803, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=31.1475409836066, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787526, Length=201, Percent_Identity=30.8457711442786, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=36, Blast_Score=123, Evalue=9e-29, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=36.9477911646586, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=33.0739299610895, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17538182, Length=210, Percent_Identity=34.7619047619048, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.9473684210526, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.3524904214559, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=29.6, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17536025, Length=266, Percent_Identity=30.8270676691729, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=27.2388059701493, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=30.1204819277108, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=29.8850574712644, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=25.1908396946565, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=26.3940520446097, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=31.3131313131313, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=30.7984790874525, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=26.8939393939394, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=29.0566037735849, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561272, Length=279, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=26.2357414448669, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=26.2548262548263, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=28.0769230769231, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=25.8883248730964, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=25.8555133079848, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=25.7936507936508, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555612, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=29.3436293436293, Blast_Score=78, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=37.3015873015873, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.4741035856574, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=32.258064516129, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=33.8461538461538, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=32.3886639676113, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=32.2709163346614, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=33.7254901960784, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24581726, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI17737361, Length=202, Percent_Identity=33.1683168316832, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=30.4, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI18859837, Length=234, Percent_Identity=29.9145299145299, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI161076933, Length=212, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24584748, Length=212, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI28574402, Length=212, Percent_Identity=29.2452830188679, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24584744, Length=212, Percent_Identity=29.2452830188679, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI281364892, Length=209, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24640492, Length=153, Percent_Identity=30.718954248366, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=208, Percent_Identity=29.8076923076923, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584752, Length=207, Percent_Identity=29.4685990338164, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24640442, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27642; Mature: 27511
Theoretical pI: Translated: 4.81; Mature: 4.81
Prosite motif: PS00061 ADH_SHORT ; PS00104 EPSP_SYNTHASE_1 ; PS00216 SUGAR_TRANSPORT_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 5.3 %Met (Translated Protein) 7.3 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 5.0 %Met (Mature Protein) 6.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEISLDAPKLFDLAGNVALVTGAGSGIGQRIAIGLAQCGADVGLLDRRTDDGLAKTADL CCCCCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH IEKAGRRSIQIAADVTSGAALDEAVARTEAELGPLTLALNAAGIANAHPAEEMEETQFQT HHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHH MMDVNLKGVFLSCQAEARAMLRNGRGSIVNIASMSGVIVNRGLNQCHYNASKAGVIHMSK HHCCCEEEEEEECCHHHHHHHHCCCCCEEEEEHHCCHHHHCCCHHHHCCCCCCCEEEEHH SMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTRLFEEQTPMQRMAGVDEMVGPAVFL HHHHHHHCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHH LSDAASFVTGVDLLVDGGFCCW HHHHHHHHHHHHHEECCCEECC >Mature Secondary Structure SEISLDAPKLFDLAGNVALVTGAGSGIGQRIAIGLAQCGADVGLLDRRTDDGLAKTADL CCCCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH IEKAGRRSIQIAADVTSGAALDEAVARTEAELGPLTLALNAAGIANAHPAEEMEETQFQT HHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHH MMDVNLKGVFLSCQAEARAMLRNGRGSIVNIASMSGVIVNRGLNQCHYNASKAGVIHMSK HHCCCEEEEEEECCHHHHHHHHCCCCCEEEEEHHCCHHHHCCCHHHHCCCCCCCEEEEHH SMAMEWVGRGIRVNTISPGYTATPMNTRPEMVHQTRLFEEQTPMQRMAGVDEMVGPAVFL HHHHHHHCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHH LSDAASFVTGVDLLVDGGFCCW HHHHHHHHHHHHHEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]