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The map label for this gene is mtgA [H]

Identifier: 150398315

GI number: 150398315

Start: 3269666

End: 3270454

Strand: Reverse

Name: mtgA [H]

Synonym: Smed_3121

Alternate gene names: 150398315

Gene position: 3270454-3269666 (Counterclockwise)

Preceding gene: 150398318

Following gene: 150398314

Centisome position: 86.48

GC content: 64.64

Gene sequence:

>789_bases
ATGGAAAACCGGGCGGACGGGAAAGAGGTGGACGGGCGGGGCGTGGACATCATTTCGGAAGAGCGCGAGGAAGCGGAATT
GCCCGCCGGCCGGCAGACGGCCGTGCGACGGACGTGGCGTGCGCGTCGTCGCCGCCTCGTTCTACTCGTGCTCTCCATCC
TGTTCCTGCCCTACGCGCTGATCTTCTTCTATCTCGCCGAGTTCATTCACCCGGTCTCTACCCTGATGCTGCGCGACCTC
GTGCTGGCGCGCGGCTATGACCGGCAATGGGTCGAGTTCGACGACATCGCGCCGGTGCTCGTCCAGTCGGTAATGATGTC
GGAGGACGGGCAGTTCTGCTCGCATGCCGGCGTCGATTGGGCTCAGATGCGCGCCGTCGTAGAGGATGCGCTCGACGGCG
GACAGACGCGCGGCGCCAGTACGATCCCGATGCAGACCGCCAAGAACCTGTTCCTCTGGAATGGCCGTTCCTTCGTGCGC
AAAGCGATGGAGCTGCCGCTCGCGGTCGCCGCCGATTTCGTCTGGAGCAAACGGCGCCTGATGGAGATTTATCTGAACGT
CGCCGAATGGGGCGAGGGCATTTACGGGATCGAAGCTGCAGCCCGGCATCATTTCGGCGTTTCGGCGGCGGAGCTCTCGC
GCCGTCAGGCTGCTCTTCTCGCCGTATCGCTGCCAAATCCGGTCGACCGCAACGCCGGCAAACCGGGGCGCGGTCTGCGG
CGTCTCGCCTCGGTGATCGAGCGCCGGGCAAGCCGCTCCGGCGGCTATATCACGTGTCTTTATGATTGA

Upstream 100 bases:

>100_bases
CAGCGCGCACAGCCTCTCGGTGATGATGCACCTTCTGAGCCTTGCCTTTTGCCAGAAAGGCCGTTCAACTTTGGCTCGCC
ATGGCATATGAGGGAGGTGG

Downstream 100 bases:

>100_bases
GATGAATCCAATTCATTGGTCTGTCGGCCTTTGATGTGGCAAGGCTGCCGTCCGGAACTTCAGGCGGAGACAAAAATCAT
GGCCAAGCTCGTCCTCTATG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MENRADGKEVDGRGVDIISEEREEAELPAGRQTAVRRTWRARRRRLVLLVLSILFLPYALIFFYLAEFIHPVSTLMLRDL
VLARGYDRQWVEFDDIAPVLVQSVMMSEDGQFCSHAGVDWAQMRAVVEDALDGGQTRGASTIPMQTAKNLFLWNGRSFVR
KAMELPLAVAADFVWSKRRLMEIYLNVAEWGEGIYGIEAAARHHFGVSAAELSRRQAALLAVSLPNPVDRNAGKPGRGLR
RLASVIERRASRSGGYITCLYD

Sequences:

>Translated_262_residues
MENRADGKEVDGRGVDIISEEREEAELPAGRQTAVRRTWRARRRRLVLLVLSILFLPYALIFFYLAEFIHPVSTLMLRDL
VLARGYDRQWVEFDDIAPVLVQSVMMSEDGQFCSHAGVDWAQMRAVVEDALDGGQTRGASTIPMQTAKNLFLWNGRSFVR
KAMELPLAVAADFVWSKRRLMEIYLNVAEWGEGIYGIEAAARHHFGVSAAELSRRQAALLAVSLPNPVDRNAGKPGRGLR
RLASVIERRASRSGGYITCLYD
>Mature_262_residues
MENRADGKEVDGRGVDIISEEREEAELPAGRQTAVRRTWRARRRRLVLLVLSILFLPYALIFFYLAEFIHPVSTLMLRDL
VLARGYDRQWVEFDDIAPVLVQSVMMSEDGQFCSHAGVDWAQMRAVVEDALDGGQTRGASTIPMQTAKNLFLWNGRSFVR
KAMELPLAVAADFVWSKRRLMEIYLNVAEWGEGIYGIEAAARHHFGVSAAELSRRQAALLAVSLPNPVDRNAGKPGRGLR
RLASVIERRASRSGGYITCLYD

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=222, Percent_Identity=39.6396396396396, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082258, Length=132, Percent_Identity=35.6060606060606, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786343, Length=141, Percent_Identity=36.1702127659575, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788867, Length=141, Percent_Identity=34.7517730496454, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 29465; Mature: 29465

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRADGKEVDGRGVDIISEEREEAELPAGRQTAVRRTWRARRRRLVLLVLSILFLPYAL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFYLAEFIHPVSTLMLRDLVLARGYDRQWVEFDDIAPVLVQSVMMSEDGQFCSHAGVDW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCH
AQMRAVVEDALDGGQTRGASTIPMQTAKNLFLWNGRSFVRKAMELPLAVAADFVWSKRRL
HHHHHHHHHHHCCCCCCCCCCCCHHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHH
MEIYLNVAEWGEGIYGIEAAARHHFGVSAAELSRRQAALLAVSLPNPVDRNAGKPGRGLR
HHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHH
RLASVIERRASRSGGYITCLYD
HHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure
MENRADGKEVDGRGVDIISEEREEAELPAGRQTAVRRTWRARRRRLVLLVLSILFLPYAL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFYLAEFIHPVSTLMLRDLVLARGYDRQWVEFDDIAPVLVQSVMMSEDGQFCSHAGVDW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCH
AQMRAVVEDALDGGQTRGASTIPMQTAKNLFLWNGRSFVRKAMELPLAVAADFVWSKRRL
HHHHHHHHHHHCCCCCCCCCCCCHHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHH
MEIYLNVAEWGEGIYGIEAAARHHFGVSAAELSRRQAALLAVSLPNPVDRNAGKPGRGLR
HHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHH
RLASVIERRASRSGGYITCLYD
HHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]