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The map label for this gene is gpmB [H]

Identifier: 150398191

GI number: 150398191

Start: 3143899

End: 3144468

Strand: Reverse

Name: gpmB [H]

Synonym: Smed_2994

Alternate gene names: 150398191

Gene position: 3144468-3143899 (Counterclockwise)

Preceding gene: 150398192

Following gene: 150398190

Centisome position: 83.15

GC content: 62.98

Gene sequence:

>570_bases
GTGAACGTATTCGTGATCAGGCATGGGGAGACCGAGTGGAGTCTGAGCGGGCAACACACGGGCACAACAGACATCCCCTT
GACCGACAGCGGACGACGACAGGCGGAAAGGATGCGGCCTGTTTTGGCTCGGCACACGTTCGCGCTCGTTCTCGTAAGCC
CGATGCAGCGGGCACGGGAGACATGTGACTTGGTGGGCCTCGGCGCCGCGGCAATCGGCGACCCAGGCTTGATAGAGTGG
AACTACGGCGAATACGAGGGTCATACACCCCAGCAAATCCAGGCGAAGAGGCCGGGCTGGCTGATTTTCCGGGATGGTTG
CCCCGGCGGCGAGACGCCGAGTCAGGTGGGGGCTCGTGTGGATCAGGTCGTGACGCGTGTCCGGGCTGCGAAGGGCGACG
TCGCGCTATTTGCGCATGGGCACGTGCTGCGCGTGCTTGCAGCGCGATGGATCGGCCTGCCACCACGCGCCGGGCAGCAT
TTTCTACTGAATACCGGCACGTTAAGCGTCCTTACCTACTACCACGAGGTACCCGCAGTGAGAGTATGGAACGGACACGC
CGCTGACTAG

Upstream 100 bases:

>100_bases
CTTGCGATCAGCGGCTGGAAGTGGGGCGTGAAAGACACGACGGCAGCGTCCCGGAAAACCTCTACGGAAGGGGACAACGT
CTGAGCCGGGAGGGCTGGAC

Downstream 100 bases:

>100_bases
AGCGAATCCGGGAAACGTGTGAGGCATTTTACGTCGGGAGTCGCATGATTACAAAGGGTTAGATCATTTCACCGTTTCGG
TGCGACATGATCCAGCCTGC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MNVFVIRHGETEWSLSGQHTGTTDIPLTDSGRRQAERMRPVLARHTFALVLVSPMQRARETCDLVGLGAAAIGDPGLIEW
NYGEYEGHTPQQIQAKRPGWLIFRDGCPGGETPSQVGARVDQVVTRVRAAKGDVALFAHGHVLRVLAARWIGLPPRAGQH
FLLNTGTLSVLTYYHEVPAVRVWNGHAAD

Sequences:

>Translated_189_residues
MNVFVIRHGETEWSLSGQHTGTTDIPLTDSGRRQAERMRPVLARHTFALVLVSPMQRARETCDLVGLGAAAIGDPGLIEW
NYGEYEGHTPQQIQAKRPGWLIFRDGCPGGETPSQVGARVDQVVTRVRAAKGDVALFAHGHVLRVLAARWIGLPPRAGQH
FLLNTGTLSVLTYYHEVPAVRVWNGHAAD
>Mature_189_residues
MNVFVIRHGETEWSLSGQHTGTTDIPLTDSGRRQAERMRPVLARHTFALVLVSPMQRARETCDLVGLGAAAIGDPGLIEW
NYGEYEGHTPQQIQAKRPGWLIFRDGCPGGETPSQVGARVDQVVTRVRAAKGDVALFAHGHVLRVLAARWIGLPPRAGQH
FLLNTGTLSVLTYYHEVPAVRVWNGHAAD

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790856, Length=187, Percent_Identity=26.7379679144385, Blast_Score=60, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322896, Length=184, Percent_Identity=37.5, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 20730; Mature: 20730

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFVIRHGETEWSLSGQHTGTTDIPLTDSGRRQAERMRPVLARHTFALVLVSPMQRARE
CEEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
TCDLVGLGAAAIGDPGLIEWNYGEYEGHTPQQIQAKRPGWLIFRDGCPGGETPSQVGARV
HHHEEECCHHHCCCCCEEEECCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
DQVVTRVRAAKGDVALFAHGHVLRVLAARWIGLPPRAGQHFLLNTGTLSVLTYYHEVPAV
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCHHEEHHHHHHCCEE
RVWNGHAAD
EEECCCCCC
>Mature Secondary Structure
MNVFVIRHGETEWSLSGQHTGTTDIPLTDSGRRQAERMRPVLARHTFALVLVSPMQRARE
CEEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
TCDLVGLGAAAIGDPGLIEWNYGEYEGHTPQQIQAKRPGWLIFRDGCPGGETPSQVGARV
HHHEEECCHHHCCCCCEEEECCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
DQVVTRVRAAKGDVALFAHGHVLRVLAARWIGLPPRAGQHFLLNTGTLSVLTYYHEVPAV
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCHHEEHHHHHHCCEE
RVWNGHAAD
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]